Suppression of the TGF-β pathway by a macrolide antibiotic decreases fibrotic responses by ocular fibroblasts in vitro by Thomas Stahnke, Beata Gajda-Deryło, Anselm G. Jünemann, Oliver Stachs, Katharina A. Sterenczak, Robert Rejdak, Julia Beck, Ekkehard Schütz, Steffen Möller, Israel Barrantes, Gregor Warsow, Stephan Struckmann, Georg Fuellen

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Drug Repurposing for Rare Orphan Diseases Using Machine Learning Techniques by Rajesh Manicavasaga, Prabin B Lamichhane, Prajjwal Kandel, Douglas A. Talbert

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Verteporfin is an effective inhibitor of HCMV replication by Woo Young Lim, Ju Hyun Lee, Youngju Choi, Keejung Yoon

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Antiproliferative and Morphological Analysis Triggered by Drugs Contained in the Medicines for Malaria Venture COVID-Box Against <i>Toxoplasma gondii</i> Tachyzoites by Andréia Luiza Oliveira Costa, Mike dos Santos, Giulia Caroline Dantas-Vieira, Rosálida Estevam Nazar Lopes, Rossiane Claudia Vommaro, Érica S. Martins-Duarte

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The potential of repurposing clemastine to promote remyelination by Reiji Yamazaki, Nobuhiko Ohno, Nobuhiko Ohno

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A Search for FDA Approved Drugs with Multiple Antiemetic Targets: A Computational-Based Drug Repositioning Study by Abdulmajeed Yunusa*1, Albashir Tahir1,2

Subjects: “…antiemetics, drug repositioning, molecular docking, fda-approved drugs…”
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Effects of prolonged exposure to diclofenac sodium on strains of Staphylococcus aureus by A. A. de Lima-e-Silva, R.G. da Silva-Filho, A. S. Viana

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Editorial: Repurposed drugs targeting cancer signaling pathways: clinical insights to improve oncologic therapies, volume II by Alma D. Campos-Parra, Gerardo Leyva-Gomez, Teresita Padilla-Benavides

Subjects: “…drug repositioning…”
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Anticancer effect of the antirheumatic drug leflunomide on oral squamous cell carcinoma by the inhibition of tumor angiogenesis by Chieko Niwata, Takayuki Nakagawa, Takako Naruse, Miyuki Sakuma, Nao Yamakado, Misaki Akagi, Shigehiro Ono, Kei Tobiume, Jing Gao, Eijiro Jimi, Kouji Ohta, Tomonao Aikawa

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Recent advances in metallodrug: Coordination-induced synergy between clinically approved drugs and metal ions by Won Kyu Kim, Jong Min An, Yeon Jin Lim, Kihun Kim, Yun Hak Kim, Dokyoung Kim

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Research on drug repositioning based on generative AI by GONG Houwu, JIN Min

Subjects: “…drug repositioning…”
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In-silico drug repositioning studies of Candida albicans Nitrogen permease reactivator 1 (Npr1) kinase by Sanjib Das, Arka Bagchi, Analava Bera, Arunima Biswas, Analabha Roy, Rik Ganguly, Amalesh Mondal, Deepanjan Chattopadhyay, Paromita Saha Mondal, Tanushree Mondal, Subhasree Samanta, Achintya Mohan Goswami, Tanima Saha

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A controlled comparative study of the effects of methotrexate and pharmacogenetic factors on arterial blood pressure and arterial stiffness in patients with rheumatoid arthritis by Arduino A. Mangoni, Michael D. Wiese, Richard J. Woodman, Salvatore Sotgia, Angelo Zinellu, Ciriaco Carru, Julie-Ann Hulin, E. Michael Shanahan, Sara Tommasi

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VLX600, an anticancer iron chelator, exerts antimicrobial effects on Mycobacterium abscessus infections by Jaehun Oh, Seaone Choi, Hyejun Seo, Dong Hyun Kim, Hyelin Kim, Duhyung Lee, Junghwa Jang, Sangkwon Jung, Ju-Young Lee, Ziyun Kim, Jae-Joon Yim, Nakwon Kwak, Bum-Joon Kim

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Identifying suppressive factors of Alzheimer’s disease through comprehensive analysis of real-world data: a single-center retrospective study by Mana Shiotani, Yuki Hyohdoh, Yutaka Hatakeyama, Hiroaki Kazui, Yoshiyasu Okuhara

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DVGEDR: a drug repositioning method based on dual-view fusion and graph enhancement mechanism in heterogeneous networks by Dongjiang Niu, Lianwei Zhang, Beiyi Zhang, Qiang Zhang, Shanyang Ding, Hai Wei, Zhen Li

Subjects: “…Drug repositioning…”
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Drugs that reverse disease transcriptomic signatures are more effective in a mouse model of dyslipidemia by Allon Wagner, Noa Cohen, Thomas Kelder, Uri Amit, Elad Liebman, David M Steinberg, Marijana Radonjic, Eytan Ruppin

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In Silico Investigation of TATA-Binding Protein as a Therapeutic Target for Chagas Disease: Insights into FDA Drug Repositioning by Carlos Gaona-López, Domingo Méndez-Álvarez, Alonzo Gonzalez-Gonzalez, Guadalupe Avalos-Navarro, Alma D. Paz-González, Adriana Moreno-Rodríguez, Benjamín Nogueda-Torres, Gildardo Rivera

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Critical dysregulated signaling pathways in drug resistance: highlighting the repositioning of mebendazole for cancer therapy by Amin Aliabadi, Amin Aliabadi, Seyed Zachariah Moradi, Sadaf Abdian, Sajad Fakhri, Javier Echeverría

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Lonafarnib Protects Against Muscle Atrophy Induced by Dexamethasone by Sanghoon Bae, Van‐Hieu Mai, Seyoung Mun, Dalong Dong, Kyudong Han, Sunghyouk Park, Jung Keun Hyun

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