How to Make the Right Choice of Proton Pump Inhibitor for Patients with Gastroesophageal Reflux Disease? by Yu. V. Evsyutina

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Medication patterns and potentially inappropriate medication in patients with metastatic breast cancer: results of the BRE-BY-MED study by Lilly Sophia Brandstetter, Anna Grau, Peter U. Heuschmann, Max Müller-Reiter, Jessica Salmen, Stefan Störk, Achim Wöckel, Jens-Peter Reese

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Proximal tubule-on-chip as a model for predicting cation transport and drug transporter dynamics by Isy Petit, Quentin Faucher, Jean-Sébastien Bernard, Perrine Giunchi, Antoine Humeau, François-Ludovic Sauvage, Pierre Marquet, Nicolas Védrenne, Florent Di Meo

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Physiologically Based Pharmacokinetic Modeling of Cannabidiol, Delta‐9‐Tetrahydrocannabinol, and Their Metabolites in Healthy Adults After Administration by Multiple Routes by Lixuan Qian, Tao Zhang, Jean Dinh, Mary F. Paine, Zhu Zhou

“…The verified models could be used to help address critical public health needs, including assessing potential drug interaction risks involving CBD and THC.…”
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Novel (Q)SAR models for prediction of reversible and time-dependent inhibition of cytochrome P450 enzymes by Sadegh Faramarzi, Arianna Bassan, Kevin P. Cross, Xinning Yang, Glenn J. Myatt, Donna A. Volpe, Lidiya Stavitskaya

“…The newly developed models will provide a faster and more effective evaluation of potential drug-drug interaction caused by metabolites.…”
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Antihypertensive drug-related problems in Vietnamese ambulatory care by Hoang Hai Nguyen, Le Anh Thu Vu, Minh-Hoang Tran, Hong Tham Pham

“…Physician acceptance of aDRP corrections could be strongly related to unnecessary/missing indication, major-to-contraindicated drug interaction, and adverse effects. These findings could improve DRP alerts and maximize treatment outcomes in Asian patients with hypertension.…”
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Recent advancements to enhance the therapeutic efficacy of antiepileptic drugs by Li Fuquan, Singh Akhilesh Vikram

“…However, drug resistance, drug-drug interaction and adverse events are common problems associated with AEDs. …”
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Effect of Staggered vs. Simultaneous Co-Administration of Bempedoic Acid on Pharmacokinetics of Pravastatin: Randomized, Cross-Over Clinical Trial in Healthy Volunteers by Felicitas Stoll, Salvatore Amato, Max Sauter, Jürgen Burhenne, Johanna Weiss, Walter E. Haefeli, Antje Blank

“…We hypothesized that the drug interaction between BA and statins could be mitigated by staggered administration. …”
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An Unexpected Interaction between Sofosbuvir/Ledipasvir and Atorvastatin and Colchicine Causing Rhabdomyolysis in a Patient with Impaired Renal Function by Shyam Patel, Jennifer Andres, Kamran Qureshi

“…We present a case of a serious drug interaction between Sof/Led and atorvastatin, in the background of CKD and colchicine use.…”
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<i>H. pylori</i> eradication therapy for patients receiving nonsteroid antiinflammatory drugs by V. T. Ivashkin, T. L. Lapina

“…Pantoprazole should be preferred at complex treatment of these patients to decrease adverse effects due to drug interaction.Conclusion. Successful and well-timed combination of eradication treatment and standalone PPI therapy is the important prerequisite in avoidance of dangerous gastro-intestinal complications at intake of NSAID and aspirin.…”
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Current Potential of Pantoprazole in Treatment and Prevention of Gastrointestinal Diseases by A. A. Sheptulin, S. S. Kardasheva, A. A. Kurbatova

“…Pharmacokinetics of pantoprazole conditions a weaker drug interaction compared to other proton pump inhibitors (PPIs), which enables its use for gastrointestinal bleeding prevention in patients receiving dual antiplatelet therapy. …”
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Current Trends in Treatment for Acid-Dependent Diseases: Clinical Efficacy and Safety of Rabeprazole by O. D. Lopina, B. K. Nurgalieva, T. L. Lapina

“…The rabeprazole properties of high acid suppression potential, persistent antisecretory effect from first day of therapy, non-enzymatic metabolism and pleiotropic action determine its high efficacy in treatment for a wide range of acid-dependent diseases at a minimal risk of drug interaction.…”
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Algorithm and Simulation of Association Rules of Drug Relationship Based on Network Model by Hui Teng, Yukun Ma, Di Teng

“…Therefore, based on the network model, this research proposed an algorithm for drug interaction under improved association rules, which achieved accurate analysis and decision-making of drug relationship. …”
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Rhabdomyolysis Induced by Coadministration of Fusidic Acid and Atorvastatin: A Case Report and Comprehensive Review of the Literature by Dimitrios Patoulias, Theodoros Michailidis, Thomas Papatolios, Rafael Papadopoulos, Petros Keryttopoulos

“…Acute renal failure can be a direct consequence of this drug-drug interaction. We present a case of a 79-year-old woman who presented to our Emergency Department with a one-week history of limb weakness, myalgia, and inability to stand and walk. …”
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Mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapy by V.О. Yarosh, V.V. Babenko, O.E. Svyrydiuk, O.J. Zharinov, O.A. Yepanchintseva, B.M. Todurov

“…An example of a possible drug-drug interaction possibly leading to reduction of the effectiveness of anticoagulant therapy is shown.…”
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Antithrombotic Medication for Cardioembolic Stroke Prevention by M. Àngels Font, Jerzy Krupinski, Adrià Arboix

“…The later exhibit stable pharmacokinetics obviating the need for coagulation monitoring or dose titration, and they lack clinically significant food or drug interaction. Moreover, they offer another potential that includes fixed dosing, oral administration, and rapid onset of action. …”
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High Performance Liquid Chromatographic Assay for the Simultaneous Determination of Posaconazole and Vincristine in Rat Plasma by Hadeel A. Khalil, Ahmed F. El-Yazbi, Tarek S. Belal, Dalia A. Hamdy

“…The assay was validated as per ICH guidelines and is appropriate for pharmacokinetics drug-drug interaction studies.…”
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Validated UPLC-MS/MS Method for Determination of Futibatinib and Its Pharmacokinetics in Beagle Dogs by Heng Li, Hao-Zhe Ding, Yi-Lin Wang, Feng Zhang, Ya-Hao Song, Xiang-Jun Qiu

“…This method would also be used to study drug-drug interaction (DDI).…”
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Lack of Clinically Meaningful Effect of Cariprazine on the Pharmacokinetics of a Combined Oral Contraceptive by Márta Erzsébet Rosa, Zoltán Juhász, Gabriella Pásztor Mészáros, Gabriella Magyar, Judit Harsányi, Balázs Szatmári, Zoltán Hujber, Máté Szabó, Margit Kapás

“…To address the uncertainty regarding the effectiveness of hormonal contraceptives during CAR co-administration and whether a second barrier method is necessary, a drug–drug interaction study with an oral contraceptive was conducted post-approval. …”
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