Suggested Topics within your search.
Suggested Topics within your search.
-
161
A dextrorotatory residues-incorporated bioactive dodecapeptide against enterohemorrhagic Escherichia coli
Published 2023-06-01Get full text
Article -
162
Dereplication of Natural Product Antifungals via Liquid Chromatography–Tandem Mass Spectrometry and Chemical Genomics
Published 2024-12-01“…Recently expanded reports of multidrug-resistant fungal infections underscore the need to develop new and more efficient methods for antifungal drug discovery. A ubiquitous problem in natural product drug discovery campaigns is the rediscovery of known compounds or their relatives; accordingly, we have integrated Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS) for structural dereplication and Yeast Chemical Genomics for bioprocess evaluation into a screening platform to identify such compounds early in the screening process. …”
Get full text
Article -
163
The Inhibitory Effect of Alisol A 24-Acetate from Alisma canaliculatum on Osteoclastogenesis
Published 2015-01-01Get full text
Article -
164
Review of Atypical Organometallic Compounds as Antimalarial Drugs
Published 2020-01-01“…Furthermore, recent developments in the field are discussed, and future applications of this emerging class of therapeutics in antimalarial drug discovery are suggested.…”
Get full text
Article -
165
-
166
Distinguishing classes of neuroactive drugs based on computational physicochemical properties and experimental phenotypic profiling in planarians.
Published 2025-01-01“…Organismal behavioral testing is needed to fill the gap, but mammalian studies are too time-consuming and cost-prohibitive for the early stages of drug discovery. Behavioral medium-throughput screening (MTS) in small organisms promises to address this need and complement in silico and in vitro HTS to improve the discovery of novel neuroactive compounds. …”
Get full text
Article -
167
Drug Repositioning for Gynecologic Tumors: A New Therapeutic Strategy for Cancer
Published 2015-01-01“…Thus, drug repositioning may become a key approach for gynecologic cancer in drug discovery.…”
Get full text
Article -
168
Generation of Rational Drug-like Molecular Structures Through a Multiple-Objective Reinforcement Learning Framework
Published 2024-12-01“…In conclusion, we have demonstrated the potential of METEOR as a practical tool for generating rational drug-like molecules in the early phase of drug discovery.…”
Get full text
Article -
169
Discovery of Antimalarial Drugs from Streptomycetes Metabolites Using a Metabolomic Approach
Published 2017-01-01“…Metabolomics approach in malaria drug discovery is still new and needs to be initiated, especially for drug research in Malaysia.…”
Get full text
Article -
170
Precision nanoparticles for drug delivery, cell therapy tracking, and theranostics
Published 2024-11-01Get full text
Article -
171
-
172
-
173
M-Polynomial and NM-Polynomial of Used Drugs against Monkeypox
Published 2022-01-01“…Since monkeypox has started to be seen in many countries without an epidemic, studies have started on new drugs used to treat this disease. Drug discovery is a challenging process. To alleviate this process, molecular descriptors used to predict the physical, chemical, and biological properties of chemical structures are studied. …”
Get full text
Article -
174
Multi-organ frailty is enhanced by periodontitis-induced inflammaging
Published 2025-02-01Get full text
Article -
175
Advancing Alzheimer's Therapy: Computational strategies and treatment innovations
Published 2025-06-01“…A comprehensive analysis of recent literature was conducted to elucidate the broad scope of Alzheimer's etiology and the limitations of conventional drug discovery approaches. Our findings underscore the critical role of computational models in elucidating disease mechanisms, identifying therapeutic targets, and expediting drug discovery. …”
Get full text
Article -
176
The Binding of BF-227-Like Benzoxazoles to Human α-Synuclein and Amyloid β Peptide Fibrils
Published 2018-09-01Get full text
Article -
177
Wilson and Walker's Principles and Techniques of Biochemistry and Molecular Biology /
Published 2018Table of Contents: “…Biochemical and molecular biological methods in life sciences studies -- Basic principles -- Cell culture techniques -- Recombinant DNA techniques and molecular cloning -- Preparative protein biochemistry -- Electrophoretic techniques -- Immunochemical techniques -- Flow cytometry -- Radioisotope techniques -- Principles of clinical biochemistry -- Microscopy -- Centrifugation and ultracentrifugation -- Spectroscopic techniques -- Basic techniques probing molecular structure and interactions -- Mass spectrometric techniques -- Fundamentals of bioinformatics -- Fundamentals of chemoinformatics -- The python programming language -- Data analysis -- Fundamentals of genome sequencing and annotation -- Fundamentals of proteomics -- Fundamentals of metabolomics -- Enzymes and receptors -- Drug discovery and development.…”
View in OPAC
Book -
178
A Tensioned Human Skin Explant Model Used for Preliminary Assessment of Chemexfoliant-Stimulated Bioeffects
Published 2025-01-01Get full text
Article -
179
Identification and analysis of pancreatic intraepithelial neoplasia: opportunities and challenges
Published 2025-01-01Get full text
Article -
180