Nitrile-aminothiol bioorthogonal near-infrared fluorogenic probes for ultrasensitive in vivo imaging by Weiping Xu, Shujuan Yi, Jie Liu, Yuyan Jiang, Jiaguo Huang

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Electrochemical Behavior of Biologically Important Indole Derivatives by Cigdem Karaaslan, Sibel Suzen

“…Use of electrochemistry is an important approach in drug discovery and research as well as quality control, drug stability, and determination of physiological activity. …”
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Catalytic asymmetric C–N cross-coupling towards boron-stereogenic 3-amino-BODIPYs by Baoquan Zhan, Li-Qing Ren, Jiayi Zhao, Hua Zhang, Chuan He

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Corrigendum to “Influenza and the risk of active tuberculosis occurrence among individuals with latent tuberculosis infection: A national cohort study in South Korea (2015–2020)” [... by Jaehee Lee, Hyewon Seo, Dohyang Kim, Jinseub Hwang, Jin-Won Kwon

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Structural basis of CXCR4 assembly and regulation by Aijun Liu, Yezhou Liu, Richard D. Ye

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Structural basis of THC analog activity at the Cannabinoid 1 receptor by Thor S. Thorsen, Yashraj Kulkarni, David A. Sykes, Andreas Bøggild, Taner Drace, Pattarin Hompluem, Christos Iliopoulos-Tsoutsouvas, Spyros P. Nikas, Henrik Daver, Alexandros Makriyannis, Poul Nissen, Michael Gajhede, Dmitry B. Veprintsev, Thomas Boesen, Jette S. Kastrup, David E. Gloriam

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Assessment of Acute and Chronic Pharmacological Effects on Energy Expenditure and Macronutrient Oxidation in Humans: Responses to Ephedrine by Antonella Napolitano, Peter R. Murgatroyd, Nick Finer, Elizabeth K. Hussey, Robert Dobbins, Steve O'Rahilly, Derek J. R. Nunez

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An electronic tongue system with automatic sample mixing function for long-term in-situ monitoring of chemical reactions by Chaoxian Jia, Yuezhong Mao, Jianxi Ying, Xiaofan Guo, Shiyi Tian, Weibo Zheng, Tao Zhang, Yufen Zhao, Kun Ding, Yan Liu

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Time-resolved compositional and dynamics analysis of biofilm maturation and dispersal via solid-state NMR spectroscopy by Yi Xue, Xue Kang

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Challenges and applications of artificial intelligence in infectious diseases and antimicrobial resistance by Angela Cesaro, Samuel C. Hoffman, Payel Das, Cesar de la Fuente-Nunez

“…This review explores AI applications in diagnostics, therapy, and drug discovery, emphasizing both strengths and areas needing improvement.…”
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FGF21 ameliorates diabetic nephropathy through CDK1-dependently regulating the cell cycle by Yudie Zhang, Yudie Zhang, Yudie Zhang, Yudie Zhang, Yudie Zhang, Fan Wang, Fan Wang, Fan Wang, Fan Wang, Chongyang Zhang, Chongyang Zhang, Chongyang Zhang, Chongyang Zhang, Fan Yao, Fan Yao, Fan Yao, Fan Yao, Bin Zhang, Bin Zhang, Bin Zhang, Bin Zhang, Yongping Zhang, Xiaobo Sun, Xiaobo Sun, Xiaobo Sun, Xiaobo Sun

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Coronil effectively inhibits the interaction of clinically relevant Omicron mutants of SARS-CoV-2 spike proteins with human ACE2 receptor by Acharya Balkrishna, Rishabh Dev, Sandeep Kumar, Anurag Varshney

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AiGPro: a multi-tasks model for profiling of GPCRs for agonist and antagonist by Rahul Brahma, Sunghyun Moon, Jae-Min Shin, Kwang-Hwi Cho

“…Abstract G protein-coupled receptors (GPCRs) play vital roles in various physiological processes, making them attractive drug discovery targets. Meanwhile, deep learning techniques have revolutionized drug discovery by facilitating efficient tools for expediting the identification and optimization of ligands. …”
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Metabolic and epigenetic regulation of macrophage polarization in atherosclerosis: Molecular mechanisms and targeted therapies by Pinglian Yang, Xiaoling Rong, Zhechang Gao, Jiaojiao Wang, Zhiping Liu

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Diversity-oriented synthesis of stereodefined tetrasubstituted alkenes via a modular alkyne gem-addition strategy by Xuan Di, Sitian Zhou, Yali Qin, Wenjun Li, Yue Zhang, Jie Zhang, Xu Shen, Jie Han, Jin Xie, Hongming Jin

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Clinical Symptoms and Types of Samples Are Critical Factors for the Molecular Diagnosis of Symptomatic COVID-19 Patients: A Systematic Literature Review by Milad Zandi, Abbas Farahani, Armin Zakeri, Sara Akhavan Rezayat, Ramin Mohammadi, Umashankar Das, Jonathan R. Dimmock, Shervin Afzali, Mohammadvala Ashtar Nakhaei, Alireza Doroudi, Yousef Erfani, Saber Soltani

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Leveraging Blockchain and AI for Pharma Supply Chain Efficiency by Mohan Venkataraman

“…AI, on the other hand, can optimize various processes, such as drug discovery, clinical trials, and supply chain logistics. …”
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Quantitative structure property relationship study of postpartum depression medications using topological indices and regression models by Gayathri K. B, S. Roy

“…Understanding the underlying molecular properties of various medications used to treat PPD is essential in contributing to the efficacy of drug discovery and development. In this study, we aim to analyze the quantitative structural property relationships (QSPR) of PPD medications using topological indices and regression models. …”
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Microfabricated sensors for non-invasive, real-time monitoring of organoids by Yoojeong Kim, Erick C. Chica-Carrillo, Hyunjoo J. Lee

“…As the next-generation biological model, organoids provide new opportunities for drug discovery, disease modeling, and personalized medicine. …”
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Bioactive compounds and probiotics–a ray of hope in COVID-19 management by Indu Bhushan, Mahima Sharma, Malvika Mehta, Shivi Badyal, Varun Sharma, Indu Sharma, Hemender Singh, Srinivas Sistla

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