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541
Biomolecular Triconjugates Formed between Gold, Protamine, and Nucleic Acid: Comparative Characterization on the Nanoscale
Published 2012-01-01“…DNA and RNA micro- and nanoparticles are increasingly being used for gene and siRNA drug delivery and a variety of other applications in bionanotechnology. …”
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542
The Impact of <i>Lactobacillus reuteri</i> on Oral and Systemic Health: A Comprehensive Review of Recent Research
Published 2024-12-01“…Future research should focus on revealing the specific pathways of action of <i>Lactobacillus reuteri</i>, screening for the most beneficial strains, determining the most effective drug delivery strategies, developing oral and systemic health products based on <i>Lactobacillus reuteri</i>, and ensuring their safety in clinical applications.…”
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543
Nanotherapeutic smart approaches for combating Alzheimer’s disease and overcoming existing obstacles: A novel eco-friendly green approach
Published 2025-06-01“…A prospective revolution in drug delivery for the treatment of AD is the use of nanomedicine. …”
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544
Global scenario of silica-associated diseases: A review on emerging pathophysiology of silicosis and potential therapeutic regimes
Published 2025-06-01“…In recent periods, a lot of attention has been focused on the development and fabrication of suitable nanocarriers for improved and sustained drug delivery in the pulmonary system. Nanoparticle-based therapeutic modality has been evaluated in in-vitro and ex-vivo silicosis models for prolongation of drug activity and improved therapeutic outcomes. …”
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545
A Combined Computational and Experimental Study on Nanoparticle Transport and Partitioning in the Human Trachea and Upper Bronchial Airways
Published 2020-06-01“…Abstract In the past few decades, the transport and deposition of aerosol in the human respiratory tract has been a crucial area of research, resulting in the identification of the toxicity pathways of inhaled pollutants and facilitating the design of efficient drug delivery systems for targeted treatment. Owing to the complexity of the tracheobronchial tree, experimental studies in vivo/in vitro have been extremely limited; hence, detailed data on the airflow and particle dynamics have been obtained predominantly through computational investigations. …”
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546
Development and Characterization of Lyophilized Chondroitin Sulfate-Loaded Solid Lipid Nanoparticles: Encapsulation Efficiency and Stability
Published 2025-01-01“…This study explores the development and characterization of lyophilized chondroitin sulfate (CHON)-loaded solid lipid nanoparticles (SLN) as an innovative platform for advanced drug delivery. <b>Background/Objectives:</b> Solid lipid nanoparticles are increasingly recognized for their biocompatibility, their ability to encapsulate diverse compounds, their capacity to enhance drug stability, their bioavailability, and their therapeutic efficacy. …”
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547
Laser-Induced Thermal Therapy in the Management of Low-Grade Gliomas: A Narrative Review
Published 2025-01-01“…Results: LITT, a minimally invasive technique, offers targeted tumor ablation with the added benefit of disrupting the blood-brain barrier to enhance drug delivery. Studies have shown that LITT can effectively reduce tumor size and improve survival rates in patients with both primary and recurrent gliomas. …”
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548
Lipoic acid-boronophenylalanine-derived multifunctional vesicles for cancer chemoradiotherapy
Published 2025-02-01“…Nanotechnology, particularly in targeted drug delivery, has emerged as a key innovation to address these limitations. …”
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549
Enhanced precise therapy of ROS-sensitive dual-layer shell nanoparticles loading quercetin on DSS-induced ulcerative colitis mice
Published 2025-01-01“…Therefore, Que@Gel-DA NPs, a ROS-sensitive nano-drug delivery system, represent a novel therapeutic approach for the clinical intervention of UC.…”
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550
Metal‐based nanomaterials and nanocomposites as promising frontier in cancer chemotherapy
Published 2023-04-01“…To improve targeted drug delivery using nano‐carriers, noteworthy research is required. …”
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551
Microwave-assisted synthesis and swelling behavior of poly lactic acid (PLA) grafted Cordia dichotoma gum-based hydrogels
Published 2025-06-01“…The swelling of CDG-g-PLA in water was measured and found to be significantly lower than CDG, making them novel candidates for drug-delivery and sustainable food packaging applications.…”
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552
Alginate Hydrogel Beads with a Leakproof Gold Shell for Ultrasound-Triggered Release
Published 2025-01-01“…<b>Background/Objectives:</b> Focused ultrasound has advantages as an external stimulus for drug delivery as it is non-invasive, has high precision and can penetrate deep into tissues. …”
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553
Recent advances in nanotechnology for Parkinson’s disease: diagnosis, treatment, and future perspectives
Published 2025-01-01“…Nanomedicine utilizes nanoparticles for targeted drug delivery, leveraging their small size and high surface area to volume ratio to cross the blood-brain barrier and deliver therapeutic agents directly to affected brain regions. …”
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554
Formation and stability of green and low-cost magnetoliposomes of the soy lecithin, stigmasterol, and β-sitosterol for hyperthermia treatments
Published 2025-01-01“…Lip-Fe3O4@lecithin with concentrations of 0.58 mg mL−1 of liposome showed high cell viability and are potential candidates for drug delivery and hyperthermia treatments in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays.…”
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555
Exosome-based targeted delivery of NF-κB ameliorates age-related neuroinflammation in the aged mouse brain
Published 2025-01-01“…Exosomes are potent therapeutics or drug delivery vehicles for various materials, including proteins and regulatory genes, to target cells. …”
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556
Psoralidin: emerging biological activities of therapeutic benefits and its potential utility in cervical cancer
Published 2024-09-01“…Therefore, further investigation is needed in area of drug delivery and mechanism of action to fully harness the beneficial effects of psoralidin. …”
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557
Noninvasive in vivo imaging of macrophages: understanding tumor microenvironments and delivery of therapeutics
Published 2025-01-01“…Noninvasive in vivo molecular imaging of macrophages is crucial for investigating intricate cellular processes, comprehending the underlying mechanisms of diseases, tracking cells and EVs’ migration, and devising macrophage-dependent drug-delivery systems in living organisms. Thus, in vivo imaging of macrophages has become an indispensable tool in biomedical research. …”
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558
Silver Nanoparticles Conjugate Attenuates Highly Active Antiretroviral Therapy-Induced Hippocampal Nissl Substance and Cognitive Deficits in Diabetic Rats
Published 2021-01-01“…The application of nanomedicine to antiretroviral drug delivery holds promise in reducing the comorbidities related to long-term systemic exposure to highly active antiretroviral therapy (HAART). …”
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559
Superparamagnetic Bifunctional Bisphosphonates Nanoparticles: A Potential MRI Contrast Agent for Osteoporosis Therapy and Diagnostic
Published 2010-01-01“…A bone targeting nanosystem is reported here which combined magnetic contrast agent for Magnetic Resonance Imaging (MRI) and a therapeutic agent (bisphosphonates) into one drug delivery system. This new targeting nanoplatform consists of superparamagnetic γFe2O3 nanoparticles conjugated to 1,5-dihydroxy-1,5,5-tris-phosphono-pentyl-phosphonic acid (di-HMBPs) molecules with a bisphosphonate function at the outer of the nanoparticle surface for bone targeting. …”
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560
Hydrogel-Based Innovations in Carpal Tunnel Syndrome: Bridging Pathophysiological Complexities and Translational Therapeutic Gaps
Published 2025-01-01“…Their ability to mimic the extracellular matrix facilitates localized drug delivery, anti-adhesion barrier formation, and tissue regeneration. …”
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