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521
Synthesis, Structural Characterization, and Preclinical Efficacy of a Novel Paclitaxel-Loaded Alginate Nanoparticle for Breast Cancer Treatment
Published 2016-01-01“…PTX was combined with ALG in a nanoparticle as a drug delivery system designed to improve breast cancer tumor cell killing. …”
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522
Navigating large-volume subcutaneous injections of biopharmaceuticals: a systematic review of clinical pipelines and approved products
Published 2024-12-01“…These findings highlight the importance of developing large-volume drug delivery systems and novel formulations to reduce injection volumes. …”
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523
A Novel Fuzzy Algorithm to Introduce New Variables in the Drug Supply Decision-Making Process in Medicine
Published 2018-01-01“…In addition, the result of the algorithm in terms of fuzzy rules and membership functions will define a fuzzy-based decision system for the drug delivery process. The method proposed is based on a Fuzzy Inference System whose structure is obtained through a decision tree algorithm. …”
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524
Development of Duloxetine Hydrochloride Tablets for Delayed and Complete Release Using Eudragit L 100
Published 2021-01-01“…Thus, duloxetine HCl when given orally needed a protective enteric coating that disable the delivery of duloxetine HCl in gastric fluid while enabling the drug delivery only in small intestine. Four different core tablets were prepared by direct compression technique, and the one which displayed quick disintegration and dissolution was chosen for enteric coating. …”
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525
Stabilizing milk-derived extracellular vesicles (mEVs) through lyophilization: a novel trehalose and tryptophan formulation for maintaining structure and Bioactivity during long-te...
Published 2025-01-01“…Abstract Extracellular vesicles (EVs) are widely investigated for their implications in cell-cell signaling, immune modulation, disease pathogenesis, cancer, regenerative medicine, and as a potential drug delivery vector. However, maintaining integrity and bioactivity of EVs between Good Manufacturing Practice separation/filtration and end-user application remains a consistent bottleneck towards commercialization. …”
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526
Enhanced Chemical Insights into Fullerene Structures via Modified Polynomials
Published 2024-01-01“…This study highlights the potential for these algebraic tools to bridge the gap between theoretical models and practical applications in nanotechnology and materials science, paving the way for innovations in drug delivery, electronic devices, and catalysis.…”
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527
The Efficacy of Amniotic Membrane Stem Cell (AMSC) Metabolite Product and Vitamin E for Wrinkles, Spots, and Pores in Photoaging
Published 2020-01-01“…It is expected that a combination of amniotic membrane stem cell metabolite product (AMSC-MP) and vitamin E after fractional CO2 laser as laser-assisted drug delivery (LADD) will provide better effects in photoaging treatment as the combination reaches the target. …”
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528
Perspectives of healthcare providers and persons with type 2 diabetes mellitus on improving glycaemic control in Kinshasa, Democratic Republic of the Congo: a qualitative study
Published 2024-07-01“…This is achieved through training of healthcare providers, equipping healthcare structures and organising a reliable drug delivery system. Healthcare providers must also act to ensure that patients get adequate support from their surroundings and the community by providing adequate information about diabetes. …”
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529
Gd3+-Doped Magnetic Nanoparticles for Biomedical Applications
Published 2018-01-01“…Magnetic nanoparticles (MNPs) made of iron oxides with cubic symmetry (Fe3O4, γ-Fe2O3) are demanded objects for multipurpose in biomedical applications as contrast agents for magnetic resonance imaging, magnetically driven carriers for drug delivery, and heaters in hyperthermia cancer treatment. …”
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530
Characterization of ZnO nanoparticles synthesized using probiotic Lactiplantibacillus plantarum GP258
Published 2025-01-01“…Additionally, the NPs were photocatalytically and electrochemically analyzed, indicating their potential use in cancer research as well as in coating and drug delivery applications.…”
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531
Advances in Deep Brain Imaging with Quantum Dots: Structural, Functional, and Disease-Specific Roles
Published 2024-12-01“…Their stability enables long-term, targeted drug delivery and photodynamic therapy, presenting potential therapeutic applications in treating brain tumors, Alzheimer’s disease, and traumatic brain injury. …”
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532
The The Evaluation of Clove oil Concentration on Physicochemical and Antimicrobial Activity in the Laponite Gel Delivery System
Published 2024-12-01“…Clove oil as an antimicrobial topical requires a drug delivery system that is easy and comfortable to apply. …”
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533
Enhanced antitumor efficacy through sustained release of 5-fluorouracil from poly(trimethylene carbonate) membranes
Published 2025-01-01“…To address these limitations, the development of novel drug delivery systems for sustained drug release is essential to improve therapeutic outcomes.MethodsThis study aimed to develop a poly(trimethylene carbonate) (PTMC) membrane capable of sustained drug release of 5-FU to enhance its antitumor activity. …”
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534
4D-Printed Magnetic Responsive Bilayer Hydrogel
Published 2025-01-01“…Despite its widespread application in targeted drug delivery, soft robotics, and smart screens, magnetic hydrogel still faces challenges from lagging mechanical performance to sluggish response times. …”
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535
A Facile Route to Fabricate CS/GO Composite Film for the Application of Therapeutic Contact Lenses
Published 2020-01-01“…Traditional contact lenses bring convenience for ophthalmic drug delivery. However, either as contact lenses or as drug carriers, traditional materials have still some drawbacks in the field. …”
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536
Glycyrrhetinic Acid-Poly(ethylene glycol)-glycyrrhetinic Acid Tri-Block Conjugates Based Self-Assembled Micelles for Hepatic Targeted Delivery of Poorly Water Soluble Drug
Published 2013-01-01“…In conclusion, the GA-PEG-GA conjugates have potential medical applications for targeted delivery of poor soluble drug delivery.…”
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537
Peptide Antigen Modifications Influence the On-Target and Off-Target Antibody Response for an Influenza Subunit Vaccine
Published 2025-01-01“…Background/Objectives: Peptide amphiphile micelles (PAMs) are an exciting nanotechnology currently being studied for a variety of biomedical applications, especially for drug delivery. Specifically, PAMs can enhance in vivo trafficking, cell-targeting, and cell interactions/internalization. …”
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538
Supramolecular discrimination and diagnosis-guided treatment of intracellular bacteria
Published 2025-01-01“…This diagnostic approach executes the significant guiding missions of screening a customized host-guest drug delivery system by disclosing the rationale behind the discrimination. …”
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539
Incorporation of recombinant proteins into extracellular vesicles by Lactococcus cremoris
Published 2025-01-01“…EVs have diagnostic potential, as they play a role in intercellular interspecies communication, and could be applied in drug delivery. In contrast to mammalian cell-derived EVs, the study of EVs from bacteria, particularly Gram-positive bacteria, received less research attention. …”
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540
Nanomechanical characterization of soft nanomaterial using atomic force microscopy
Published 2025-04-01“…Moreover, AFM paves the way for innovative therapeutic approaches in designing effective drug delivery systems by providing insights into the physical properties of soft nanoparticles and the binding affinity of target moieties. …”
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