Changes in alcohol consumption among Belgian adults participating in the internet-based one-month-abstinence campaign ‘Tournée Minérale’ by Annelies Thienpondt, Jelle Van Cauwenberg, Joris Van Damme, Gera E. Nagelhout, Benedicte Deforche

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Factors associated with uptake and acceptability of cervical cancer screening among female sex workers in Northeastern Uganda: A cross-sectional study. by Ronald Opito, Emmanuel Tiyo Ayikobua, Hellen Akurut, Susan Alwedo, Saadick Mugerwa Ssentongo, Walter Drake Erabu, Lazarus Oucul, Musa Kirya, Lameck Lumu Bukenya, Elly Ekwamu, Abraham Ignatius Oluka, Samuel Kabwigu, Emmanuel Othieno, Amos Deogratius Mwaka

“…<h4>Methods</h4>This was a cross-sectional study conducted among 423 FSWs aged 18-49 years attending care at six health facilities serving Key Populations (FSWs, Men who have sex with men, transgender people, people who inject drugs and people in prisons) in the Teso sub-region. …”
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Evaluation of Tumour Necrosis Factor Alpha, Interleukin-2 Soluble Receptor, Nitric Oxide Metabolites, and Lipids as Inflammatory Markers in Type 2 Diabetes Mellitus

“…To restrict the influence of variables that could interfere in the interpretation of data, subjects with obesity and/or acute or chronic inflammatory disease, haemoglobinopathies, recent use of antibiotics, antiinflammatory drugs, and trauma were excluded. Type 2 DM patients (<mml:math alttext="$n=39$"> <mml:mi>n</mml:mi> <mml:mo>=</mml:mo> <mml:mn>39</mml:mn> </mml:math>; age <mml:math alttext="$53.3pm 9.0$"> <mml:mn>53.3</mml:mn> <mml:mo>&#x00B1;</mml:mo> <mml:mn>9.0</mml:mn> </mml:math> years; median glycated haemoglobin <mml:math alttext="$A_{1c} < 8\%$"> <mml:msub> <mml:mtext>A</mml:mtext> <mml:mrow> <mml:mtext>1c</mml:mtext> </mml:mrow> </mml:msub> <mml:mo>&#x003C;</mml:mo> <mml:mn>8</mml:mn> <mml:mi>&#x0025;</mml:mi> </mml:math>) presented higher levels of TNF-<mml:math alttext="$alpha$"> <mml:mi>&#x03B1;</mml:mi> </mml:math>, triglycerides (<mml:math alttext="$P < .01$"> <mml:mi>P</mml:mi> <mml:mo>&#x003C;</mml:mo> <mml:mn>.01</mml:mn> </mml:math>), NO<mml:math alttext="$^x$"> <mml:msup> <mml:mi/> <mml:mi>x</mml:mi> </mml:msup> </mml:math> and sIL-2R (<mml:math alttext="$P < .05$"> <mml:mi>P</mml:mi> <mml:mo>&#x003C;</mml:mo> <mml:mn>.05</mml:mn> </mml:math>) than control group (<mml:math alttext="$n=28$"> <mml:mi>n</mml:mi> <mml:mo>=</mml:mo> <mml:mn>28</mml:mn> </mml:math>; age <mml:math alttext="$39.7pm 14.1$"> <mml:mn>39.7</mml:mn> <mml:mo>&#x00B1;</mml:mo> <mml:mn>14.1</mml:mn> </mml:math> years). …”
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Genomic and resistome analysis of Salmonella enterica isolates from retail markets in Yichun city, China by Xiaowu Jiang, Abubakar Siddique, Li Chen, Lexin Zhu, Haiyang Zhou, Li Na, Chenghao Jia, Yan Li, Min Yue

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Thrombus composition and its implication in ischemic stroke assessment and revascularization treatments by Juan Marta-Enguita, Florencio J.D. Machado, Josune Orbe, Roberto Muñoz

“…Understanding of these pathways has enabled the development of adjuvant therapies capable of enhancing current fibrinolytic drugs and/or increasing the efficacy of endovascular treatments. …”
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Composición del trombo e implicaciones en la caracterización y el tratamiento en el ictus isquémico by J. Marta-Enguita, F.J.D. Machado, J. Orbe, R. Muñoz

“…An adequate knowledge of this pathways has allowed to develop adjuvant therapies capable of enhance current fibrinolytic drugs and/or increase efficacy of endovascular treatments. …”
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Association of sodium–glucose cotransporter-2 inhibitors with mortality across the spectrum of myocardial infarction: a systematic review and meta-analysis by Michele Maremmani, Ramin Ebrahimi, Marco Centola, Felice Achilli, Valentina Capone, Eduardo Bossone, Christian Templin, Davide Di Vece

“…Additionally, the role of type 2 diabetes mellitus (T2DM) and heart failure (HF) in modulating the effectiveness of these drugs post-MI are not fully understood. This meta-analysis aimed to assess the association of SGLT2 inhibitors with all-cause mortality in post-MI patients and to explore key moderators influencing this benefit. …”
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Harnessing Big Heterogeneous Data to Evaluate the Potential Impact of HIV Responses Among Key Populations in Sub-Saharan Africa: Protocol for the Boloka Data Repository Initiative by Refilwe Nancy Phaswana Mafuya, Edith Phalane, Amrita Rao, Kalai Willis, Katherine Rucinski, K Alida Voet, Amal Abdulrahman, Claris Siyamayambo, Betty Sebati, Mohlago Seloka, Musa Jaiteh, Lerato Lucia Olifant, Katharine Journeay, Haley Sisel, Xiaoming Li, Bankole Olatosi, Neset Hikmet, Prashant Duhoon, Francois Wolmarans, Yegnanew A Shiferaw, Lifutso Motsieloa, Mashudu Rampilo, Stefan Baral

“… BackgroundIn South Africa, there is no centralized HIV surveillance system where key populations (KPs) data, including gay men and other men who have sex with men, female sex workers, transgender persons, people who use drugs, and incarcerated persons, are stored in South Africa despite being on higher risk of HIV acquisition and transmission than the general population. …”
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Multi-omics unveils strain-specific neuroactive metabolite production linked to inflammation modulation by Bacteroides and their extracellular vesicles by Basit Yousuf, Walid Mottawea, Galal Ali Esmail, Nazila Nazemof, Nour Elhouda Bouhlel, Emmanuel Njoku, Yingxi Li, Xu Zhang, Zoran Minic, Riadh Hammami

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Effectiveness and Safety of the TRIO Optimal Health Management Program in Patients With Type 2 Diabetes Mellitus Initiating Basal Insulin Therapy: Prospective Observational Real-Wo... by Chenxi Li, Lixin Guo, Lixin Shi, Li Chen, Liming Chen, Yaoming Xue, Hong Li, Yuzhen Liang, Jing Yang, Weimin Wang, Dalong Zhu

“…The mean baseline HbA1c was 9.2%, the mean duration of diabetes was 7.3 years, and 80.4% (1,59,930/1,98,969) of patients were using BI with oral antihyperglycemic drugs. After the intervention, mean HbA1c decreased by –2.59% from baseline, with 55.6% (28,858/51,912) achieving the target HbA1c level of <7%. …”
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Multi-level analysis of gut microbiome extracellular vesicles-host interaction reveals a connection to gut-brain axis signaling by Walid Mottawea, Basit Yousuf, Salma Sultan, Tamer Ahmed, JuDong Yeo, Nico Hüttmann, Yingxi Li, Nour Elhouda Bouhlel, Hebatoallah Hassan, Xu Zhang, Zoran Minic, Riadh Hammami

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Evaluation of in-vitro and in-silico antidiabetic potential, glucose metabolism, antioxidant, cytotoxicity and phytochemical content of Ipomoea bolusiana Schinz and Ipomoea crassip... by Garland Kgosi More, Nolitha Nkobole, Charmy Twala, Sechaba Machedi, Tebogo Amos Moswetsa, Ramakwala Christinah Chokwe

“…Despite efforts to treat or manage this disease, current therapeutic agents have detrimental side effects, presenting a considerable need to develop new effective drugs with fewer adverse effects. The aim of the study: This study aimed to evaluate the inhibitory capacity of I. bolusiana and I. crassipe plant extracts on α-amylase enzyme and to assess the antioxidant capacity. …”
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Heart disease in pregnancy and adverse outcomes: an umbrella review by Jiani Zhang, Jiani Zhang, Yuxin Ren, Yuxin Ren, Bingjie Li, Qi Cao, Qi Cao, Xiaodong Wang, Xiaodong Wang, Haiyan Yu, Haiyan Yu

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Utilisation of alcohol-related treatment after a first alcohol use disorder diagnosis in Hamburg, Germany by Jakob Manthey, Kilian Huß, Sven Buth, Ludwig Kraus, Anna Schranz, Carolin Kilian, Jürgen Gallinat, Ingo Schäfer, Bernd Schulte

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Integrated microbiome, transcriptome and metabolome insight into the alleviating mechanisms of sheep milk in a DSS-induced colitis mouse model by Wenna Yao, Ruilin Du, Shuo Yan, Teligun Bao, Huimin Zhang, Fang Yang, Yue Xue, Yulong Zhao, Siqin Bao, Xihe Li, Yongli Song

“…The latest studies have revealed the adverse effects of drugs on people's health. Numerous studies have shown that animal milk can effectively protect the intestinal mucosa and alleviate UC symptoms. …”
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Comparison of the efficacy and safety of Landiolol and Esmolol in critically ill patients: a propensity score-matched study by Xiang Si, Hao Yuan, Rui Shi, Wenliang Song, Jiayan Guo, Jinlong Jiang, Tao Yang, Xiaoxun Ma, Huiming Wang, Minying Chen, Jianfeng Wu, Xiangdong Guan, Xavier Monnet

“…Generalized estimating equations (GEE) were used to compare heart rate between two drugs. The primary outcome was heart rate control, while secondary outcomes included hemodynamic response, hospital length of stay (HLOS) and ICU length of stay (ICULOS). …”
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Diagnostics and treatment of gastroesophageal reflux disease: clinical guidelines of the Russian gastroenterological association by V. T. Ivashkin, I. V. Mayev, I. . A.s. Trukhmanov, Ye. K. Baranskaya, O. B. Dronova, O. V. Zayratyants, R. G. Sayfutdinov, A. A. Sheptulin, T. L. Lapina, S. S. Pirogov, Yu. A. Kucheryavy, O. A. Storonova, D. N. Andreyev

“…Adsorbents are applied as monotherapy at non­ erosive reflux disease, and as a component of comprehensive GERD treatment, especially of the cases of mixed (acid + biliary) refluxes. Prokinetic drugs promote recovery of a normal physiological state of the esophagus, controlling the pathogenic mechanisms of GERD, reducing the number of transient lower esophageal sphincter relaxations and improving esophageal clearance due to stimulation of the lower gastrointestinal motor function. …”
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Evaluation of Yield and Yield Components of Different Ecotypes of Black Cumin (Nigella sativa L.) to Planting Date in Gorgan by Mohammad Sadeq Ashrafi, Farshid Ghaderi-Far, Elias Soltani, Ebrahim Zeinali, Asieh Siahmarguee

“…Medicinal plants are a source of biomolecules with therapeutic potential and as a lead to develop new drugs. Black cumin (*Nigella sativa* L.), often referred to as a "miracle herb," is a medicinal plant that has been used worldwide for centuries in the treatment and prevention of diseases such as cancer and diabetes. …”
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The comparative analysis of the influence of bisoprolol and carvedilol on the course of heart failure of ischemic origin in patients with concomitant atrial fibrillation and diabet... by N.M. Kulaiets, V.M. Kulaiets

“…With the use of carvedilol compared to bisoprolol, the risk of RH is lower in HF patients with AF with reduced LVEF (OR = 0.412, p = 0.047) and in patients with a combination of AF and type 2 diabetes (OR = 0.096, p = 0.044). These drugs have the same effectiveness in patients with sinus rhythm, regardless of the HF phenotype and the presence of concomitant DM. …”
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Global research trends in Chinese medicine for the treatment of non-alcoholic fatty liver disease (NAFLD): A bibliometric study by Kangjie li, Jie Wang, Ming Dang, Runxin Ren, Maomao Fu, Jing Wang, Qiao Zhang, Chongbo Zhao

“…Currently, no FDA-approved drugs are available for its treatment. However, Traditional Chinese Medicine (TCM) has gained attention for its unique theoretical framework and therapeutic strategies, particularly its potential to improve liver health by modulating liver function. …”
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