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12562
Analysis of central retinal microcirculation in glaucoma after neuroretinoprotective treatment
Published 2021-03-01“…Conventional treatment for glaucomatous optic neuropathy (antioxidants, vasodilators, nootropic drugs, and retinoprotectors) was performed in the control group.…”
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12563
Completely conserved VP2 residue K140 of KREMEN1-dependent enteroviruses is critical for virus-receptor interactions and viral infection
Published 2025-02-01“…Licensed inactivated EV-A71 vaccines do not provide cross-protection against other enteroviruses. There are no drugs specifically for HFMD. KREMEN1 (KRM1) serves as the cellular receptor for many HFMD-related enteroviruses, including CVA2–CVA6, CVA10, and CVA12. …”
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12564
Evolution of human genes encoding cell surface receptors involved in the regulation of appetite: an analysis based on the phylostratigraphic age and divergence indexes
Published 2023-12-01“…A large number of exogenous ligands of various origins, including drugs, are known for cell surface receptors, which accounts for interest in them from biomedical researchers. …”
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12565
Is Intra-articular Platelet-rich Plasma Injection Safe and Effective in Osteoarthritis Knee? A Prospective Study: A Case Series
Published 2024-01-01“…Background: Osteoarthritis (OA) of the knee is the most common slowly progressive chronic degenerative joint disease, characterized by varying degrees of loss of joint cartilage with local inflammation, usually affecting the elderly population. If oral drugs are ineffective, intra-articular injections (corticosteroids, viscous supplements, and blood-derived products) can be offered as another nonoperative modality. …”
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12566
Neuropsychiatric profile in tuberous sclerosis complex patients with epilepsy
Published 2025-01-01“…Despite advances in treatment options, including mTOR inhibitors and newer antiepileptic drugs, unmet needs remain in the comprehensive care of TSC patients. …”
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12567
Profil Penderita Penyakit Tuberkulosis Paru BTA Positif yang Ditemukan di BP4 Lubuk Alung periode Januari 2012 – Desember 2012
Published 2014-05-01“…History of previous anti tuberculosis drugs (OAT) we found in 11.3%. And 99% are referred to hospitals and health care units nearby. …”
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12568
Building resilient cattle through better management of buffalo health
Published 2023-11-01“…Therefore, interventions do not necessarily have to be done through drugs. Resilience development involves maximizing immunity, based on genetic programs and selection for individual health and product; In health management strategies that strengthen mother/child interaction from birth; In which the colostrum is guaranteed in time and form; In which anthelmintic treatments respond to a rational use on populations with parasitic pathological loads, and that have a minimum environmental impact (on dung insects, grassland ecosystems and edaphic factors), or on the dynamics of the ecosystems; Where the (restricted and cautious) use of antimicrobials prevents the continued proliferation of resistance, nor compromises human health. …”
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12569
Hubungan Tindakan Pemberantasan Sarang Nyamuk (PSN) dengan Keberadaan Jentik Vektor Chikungunya di Kampung Taratak Paneh Kota Padang
Published 2016-09-01“…There is no relationship between maintain a larva-eating fish (p=0,760), lighting and ventilation (p=0.053) , hang clothes in the room (p=0.068) , install wire gauze (p=0.274), clean the pot/birdbath (p=0.915), use of mosquito nets (p=0.619) , use of anti-mosquito drugs (p=0.209) and cover the holes of trees (p=0.123) to the presence of larvae Chikungunya vector.…”
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12570
Choice regularities of antihypertensive therapy regimens of primary open-angle glaucoma in conditions of real clinical practice
Published 2018-09-01“…With higher-level stages of the glaucoma, combinations of drugs and penetrating glaucoma surgery prevail.<br> <br> <b>Key words:</b> glaucoma, intraocular pressure, beta-adrenoblockers, prostaglandin analogues, combination therapy, therapy regimens.…”
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The effect of nursing care provided to coronary intensive care patients according to their circadian rhythms on sleep quality, pain, anxiety, and delirium: a randomised controlled...
Published 2025-02-01“…Patients with intermediate chronotype, delirium, on ventilator support, or using sedative drugs were excluded. The chronotypes of the participants were determined, and the patients in the intervention group were given nursing care by their circadian rhythms. …”
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12573
Human-Centered Design of an mHealth Tool for Optimizing HIV Index Testing in Wartime Ukraine: Formative Research Case Study
Published 2025-01-01“…The study involved 3 steps: formative HCD, including in-depth individual interviews with clients, such as men who have sex with men and people who inject drugs, and internet-based design workshops with HCWs from rural and urban HIV clinics in Chernihiv and Dnipro; software platform assessment and heuristic evaluation, including assessment of open-source mHealth platforms against CASI-Plus requirements, prototype development, and testing of the REDCap (Research Electronic Data Capture) prototype based on usability heuristics; and usability walk-throughs, including simulated cases with HCWs and clients. …”
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12574
CD36 enrichment in HER2-positive mesenchymal stem cells drives therapy refractoriness in breast cancer
Published 2025-01-01“…Consistently, both in vitro and in vivo dual blockade of CD36 and HER2 increased the anti-CSC efficacy of anti-HER2 drugs favoring the transition of the therapy resistant mesenchymal CSCs into therapy-sensitive mesenchymal-epithelial transition (MET)-like epithelial state. …”
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12575
Redefining outcomes of ventricular arrhythmia for SGLT2 inhibitor medication in heart failure patients: a meta-analysis of randomized controlled trials
Published 2025-02-01“…The primary outcomes of interest were incidences of VAs and sudden cardiac death (SCD) between the groups receiving SGLT2 inhibitors and the control drugs. For the outcomes observed in the populations of the included trials and in specific subgroups, hazard ratios (HRs) and 95% confidence intervals (CIs) were pooled and meta-analysed across the analyses. …”
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12576
<i>Cichorium intybus</i> L. Oligo-Polysaccharides (CIO) Exerts Antianxiety and Antidepressant Effects on Mice Experiencing Behavioral Despair and Chronic Unpredicted Mild Stress
Published 2025-01-01“…From the fifth week of stress, the corresponding drugs were administered by gavage until the end of the behavioral tests. …”
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12577
Dynamics of cortisol levels and the state of vitamin D supply during the full-scale war in Ukraine in patients with type 2 diabetes mellitus
Published 2024-11-01“…Exclusion criteria were as follows: T2DM with severe chronic complications, HbA1c level < 7 %, acute inflammatory processes, oncological diseases, body mass index ≥ 40 kg/m2, intake of antidepressants, vitamin D drugs less than 2 months before the study. The average level of 25(OH)D, serum and salivary cortisol were studied every year from 2021 to 2024. …”
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Treatment-related Hypertension as a Prognostic Factor for De Novo Metastatic Hormone-sensitive Prostate Cancer: A Retrospective Real-world Evidence Study
Published 2025-01-01“…Data on clinical variables, antihypertensive drugs, and blood pressure were collected from treatment initiation to 7 mo from ADT start. …”
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12579
Synthesis and Antifungal Activity of Fmoc-Protected 1,2,4-Triazolyl-α-Amino Acids and Their Dipeptides Against <i>Aspergillus</i> Species
Published 2025-01-01“…Further research into their in vivo efficacy and safety profiles is warranted to fully realize their potential as antifungal drugs in clinical and agricultural settings.…”
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12580
Prevalence and Related Risk Factors of Intestinal Parasitosis among Private School-Going Pupils of Dharan Submetropolitan City, Nepal
Published 2021-01-01“…Therefore, integration of control measures such as provision of clean and safe drinking water, improved sanitation and hygiene, with biannual administration of drugs are necessary for effective eradication of parasitic infections.…”
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