Sexual maturity staging and affecting immune-hormonal factors in children aged 6-18 years living with HIV: experience from tertiary care center in North India by Ashwini Shivannavar, Alok Hemal, Hema Gupta Mittal

“…No statistically significant association was observed with CD4 categories (p = 0.3), viral load categories (p = 0.2), age at ART initiation, and BMI categories with pubertal stages. Among antiretroviral drugs, less than 50% of children on abacavir, zidovudine, and lopinavir/ritonavir had attained pubertal onset (in girls, breast stage ≥ 2; in boys, testicular volume (TV) stage ≥ 2). …”
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Benefits of a Juvenile Arthritis Support Program (JASP-1) for children recently diagnosed with Juvenile Idiopathic Arthritis and their parents by Karina Mördrup, Johanna Granhagen Jungner, Eva Broström, Karin Palmblad, Cecilia Bartholdson

“…Abstract Background Medical treatment for children with Juvenile Idiopathic Arthritis (JIA) has improved radically since the development of biological disease-modifying antirheumatic drugs. However, children suffer from pain and anxiety, and parents often experience loneliness and lack of support. …”
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Comparing the effects of Mycozin and Clotrimazole 1% creams on vaginal candidiasis: a triple-blinded randomized controlled trial by Khadije Hajizadeh, Zahra Alivand, Vahideh Rahmani, Leila Mehrannia, Sanam Nami, Behrooz Shokouhi, Mojgan Mirghafourvand

“…The resistance to azole compounds, and the side effects of chemical drugs have been reported following azole therapy. …”
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Artrosis: ¿cambios degenerativos o cambios adaptativos? Consejos educativos breves en la consulta de atención primaria by Gema Izquierdo Enríquez, María Victoria García Espinosa, Isabel Prieto Checa, María Fernández de Paúl, Patricia Moreno Carrero, Silvia Fernanda García Vila

“…Moreover, there are no disease-modifying drugs or curative treatment at present; the basic or first-line treatment is non-pharmacological, based on education and physical exercise.The presence of degenerative changes in imaging tests is present in a high percentage of the general asymptomatic population, i.e. in those who have no pain or functional limitation, and this percentage increases progressively with age. …”
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How to publish a new fungal species, or name, version 3.0 by M. Catherine Aime, Andrew N. Miller, Takayuki Aoki, Konstanze Bensch, Lei Cai, Pedro W. Crous, David L. Hawksworth, Kevin D. Hyde, Paul M. Kirk, Robert Lücking, Tom W. May, Elaine Malosso, Scott A. Redhead, Amy Y. Rossman, Marc Stadler, Marco Thines, Andrey M. Yurkov, Ning Zhang, Conrad L. Schoch

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Single-vehicle injury crashes on rural roads in Iceland: contribution of unforgiving roadsides to fatal and serious injuries of vehicle occupants by Audur Thora Arnadottir, Gudmundur F. Ulfarsson, Sungyop Kim

“…Not a single foreign tourist driver in this data was noted as being under the influence of alcohol or illegal drugs. To strengthen the analysis of the contribution of roadside elements to the severity of run-off-road crashes and to monitor the effects of improvements in the future, it is recommended that additional information on roadside elements be coded and added to the standard police record crash data. …”
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Comprehensive Analysis and Functional Characteristics of Differential Expression of N6-Methyladenosine Methylation Modification in the Whole Transcriptome of Rheumatoid Arthritis by Lei Wan, Jian Liu, Chuanbing Huang, Ziheng Zhu, Kun Wang, Guanghan Sun, Lei Zhu, Zhongxiang Hu

“…The discovery of m6A methylation-modifying genes in this study may provide a fresh perspective on the development of drugs for RA treatment. High-throughput sequencing combined with methylated RNA immunoprecipitation (MeRIP-seq) and RNA sequencing were used to assess whole-transcriptome m6A modifications in the synovium of patients with RA. …”
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Therapeutic Efficacy of Ultrasound-Guided High-Voltage Long-Duration Pulsed Radiofrequency for Pudendal Neuralgia by Feng Ji, Shuzhuan Zhou, Caixia Li, Yongyan Zhang, Hua Xu

“…Six patients were treated with nonsteroidal drugs for a short time. All patients stopped taking medication finally. …”
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Efficacy and prognosis of dapagliflozin in the treatment of patients with acute myocardial infarction complicated with type 2 diabetes in Xining area by Jinping Chai, Delian Li, Yanmin Liu, Xiaoling Su

“…There were no significant differences in the number of coronary artery lesions, treatment regimens, cardiovascular and hypoglycemic drugs between the two groups (P > 0.05). However, up to dapagliflozin group of patients after discharge significantly lower than the control group, the incidence of cardiovascular adverse events at dapagliflozin group of 4 cases of heart failure and cardiovascular death in 1 case and control group in heart failure 13 cases, 10 cases of cardiovascular death, cerebral hemorrhage 2 cases died. …”
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miRNA Expression Profile and Effect of Wenxin Granule in Rats with Ligation-Induced Myocardial Infarction by Aiming Wu, Lixia Lou, Jianying Zhai, Dongmei Zhang, Limin Chai, Bo Nie, Haiyan Zhu, Yonghong Gao, Hongcai Shang, Mingjing Zhao

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Immune profiling of human vestibular schwannoma secretions identifies TNF-α and TWEAK as cytokines with synergistic potential to impair hearing by Sasa Vasilijic, Richard Seist, Zhenzhen Yin, Lei Xu, Konstantina M. Stankovic

“…The mechanisms underlying this SNHL are incompletely understood and currently, there are no drugs FDA approved specifically for VS. This knowledge gap significantly limits the development of effective treatments aimed at preventing, stabilizing, or reversing VS-induced SNHL. …”
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Karakteristik Pasien Hipertensi di Bangsal Rawat Inap SMF Penyakit Dalam RSUP DR. M. Djamil Padang Tahun 2013 by Bagus Sedayu, Syaiful Azmi, Rahmatini .

“…Amlodipine is antihypertensive drugs that often used with a percentage of 31.6%. …”
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The epidemiology and unmet need of migraine in five european countries: results from the national health and wellness survey by Gianluca Coppola, Joshua D. Brown, Amanda R. Mercadante, Sheila Drakeley, Nikoletta Sternbach, Aaron Jenkins, Karin Hygge Blakeman, Astrid Gendolla

“…Current treatment patterns revealed that 79.7% of respondents were receiving some form of migraine treatment, with non-steroidal anti-inflammatory drugs (NSAIDs), analgesics, and triptans being the most commonly reported prescription medications. …”
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Reversal and prevention of deregulated autophagy in cutaneous autoimmune disorders—a pilot study on vitiligo with nutrigenomics based approach of “Maximum Nutrition and Minimum Med... by Suruchi Garg, Murlidhar Rajagopalan, Anupa Mary George, Hemangi Parwani, Titiksha Hans

“…Conclusion: Nutritious diet aimed at correction of underlying protein and micronutrient deficiency with special emphasis on circadian rhythm may arrest the natural progression of disease at an early stages of the disease and prime the body for oral immunosuppressive drugs. This approach may prevent the recurrence in patients already stabilized with standard care of therapeutics and surgery in future.…”
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Predicting 28-day all-cause mortality in patients admitted to intensive care units with pre-existing chronic heart failure using the stress hyperglycemia ratio: a machine learning-... by Xiao-han Li, Xing-long Yang, Bin-bin Dong, Qi Liu

“…Subgroup analysis found that none of the potential risk factors, such as demographics, comorbidities, and drugs, affected the relationship (P for interaction > 0.05). …”
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The Quality of Life in Heart Failure Reduced Ejection Fraction (HFrEF) Patients: A Phenomenon of Obesity Paradox by Yogi Puji Rachmawan, Witri Pratiwi, Helda Helda

“…Samples were HFrEF patients who had received medication at the HF clinic for at least 6 months and the patient must have received optimal guidelines directed medical therapy (GDMT) with at least 3 pillar drugs according to Indonesian heart failure guidelines. …”
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Therapeutic Values of Earthworm Species Extract from Azad Kashmir as Anticoagulant, Antibacterial, and Antioxidant Agents by Rozina Ghulam Mustafa, Andleeb Dr Saiqa, Jorge Domínguez, Madiha Jamil, Saira Manzoor, Samna Wazir, Bushra Shaheen, Asma Parveen, Rida Khan, Shaukat Ali, Nazish Mazhar Ali, Fatima Jalal, Sadaf Azad Raja

“…Therefore, the development of new therapeutic drugs from invertebrates could be effective and potential for the prevention of the emergence of multidrug-resistant bacteria.…”
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Association Between GABRG2 and Self-Rating of the Effects of Alcohol in a French Young Adult Sample by Moe JS, Bramness JG, Bolstad I, Mørland JG, Gorwood P, Ramoz N

“…Jenny Skumsnes Moe,1,2 Jørgen G Bramness,1– 4 Ingeborg Bolstad,1,5 Jørg Gustav Mørland,3,6 Philip Gorwood,7,8 Nicolas Ramoz7,8 1Research Center for Substance Use Disorders and Mental Illness, Innlandet Hospital Trust, Brumunddal, Norway; 2Institute for Clinical Medicine, The Arctic University of Norway, Tromsø, Norway; 3Department of Alcohol, Tobacco, and Drugs, Norwegian Institute of Public Health, Oslo, Norway; 4Section for Clinical Addiction Research, Oslo University Hospital, Oslo, Norway; 5Department of Health and Social Science, Inland Norway University of Applied Sciences, Elverum, Norway; 6Institute of Clinical Medicine, University of Oslo, Oslo, Norway; 7Université Paris Cité, Inserm U1266, Institut de Psychiatrie et Neurosciences de Paris (IPNP), Team Vulnerability of Psychiatric and Addictive Disorders, Paris, France; 8GHU PARIS Psychiatrie & Neurosciences, Hôpital Sainte-Anne, CMME, Paris, FranceCorrespondence: Jenny Skumsnes Moe, Research Center for Substance Use Disorders and Mental Illness, Innlandet Hospital Trust, P.O. …”
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Voriconazole Pharmacokinetics Administered at 4 mg/kg IM and IV in Nursehound Sharks (<i>Scyliorhinus stellaris</i>) Under Human Care by Daniela Cañizares-Cooz, Daniel García-Párraga, Sonia Rubio-Langre, Teresa Encinas, Pablo Morón-Elorza

“…The use of azole antifungal drugs, especially voriconazole, has shown promise as a potential treatment option for fungal infections in elasmobranchs, with favorable outcomes in some registered cases. …”
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Hubungan OAINS pada Pengobatan Dismenorea dengan Kejadian Dispepsia pada Mahasiswi Fakultas Kedokteran Universitas Andalas by Siti Dwiaulia Risnomarta, Arnelis ., Ernawati .

“…Non-steroidal anti-inflammatory drugs (NSAIDs) are the most common treatment for primary dysmenorrhea. …”
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