Longitudinal mitochondrial bioenergetic signatures of blood monocytes and lymphocytes improve during treatment of drug-susceptible pulmonary tuberculosis patients by Bridgette M. Cumming, Kelvin W. Addicott, Fernanda Maruri, Fernanda Maruri, Vanessa Pillay, Rukaya Asmal, Sashen Moodley, Beatriz Barreto-Durate, Beatriz Barreto-Durate, Mariana Araújo-Pereira, Mariana Araújo-Pereira, Matilda Mazibuko, Zoey Mhlane, Nikiwe Mbatha, Khadija Khan, Senamile Makhari, Farina Karim, Lauren Peetluk, Alexander S. Pym, Mahomed Yunus S. Moosa, Yuri F. van der Heijden, Yuri F. van der Heijden, Yuri F. van der Heijden, Timothy S. Sterling, Timothy S. Sterling, Bruno B. Andrade, Bruno B. Andrade, Alasdair Leslie, Alasdair Leslie, Alasdair Leslie, Adrie J. C. Steyn, Adrie J. C. Steyn, Adrie J. C. Steyn

“…In this study, the rates of oxidative phosphorylation (OXPHOS) and glycolysis in circulating lymphocytes and monocytes of patients with drug-susceptible TB at diagnosis, 2 months, and 6 months during treatment, and 12 months after diagnosis were investigated using extracellular flux analysis. …”
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Use of Healthcare Claims Data to Generate Real-World Evidence on Patients With Drug-Resistant Epilepsy: Practical Considerations for Research by Nicole Stamas, Tom Vincent, Kathryn Evans, Qian Li, Vanessa Danielson, Reginald Lassagne, Ariel Berger

“…There are limited examples of comprehensive methodology for the generation of RWE on patients who have undergone neuromodulation for drug-resistant epilepsy (DRE). This is likely due, at least in part, to the many challenges inherent in using real-world data to define DRE, neuromodulation (including type implanted), and related outcomes of interest. …”
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Drug interactions in patients with alcohol use disorder: results from a real-world study on an addiction-specific ward by Sebastian Schröder, Christina Massarou, Tabea Pfister, Stefan Bleich, Phileas Johannes Proskynitopoulos, Johannes Heck, Martin Schulze Westhoff, Alexander Glahn

“…Therapeutic Advances in Drug Safety…”
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Influence of different formulations and process parameters during the preparation of drug-loaded PLGA microspheres evaluated by multivariate data analysis by Vysloužil Jakub, Doležel Petr, Kejdušová Martina, Mašková Eliška, Mašek Josef, Lukáč Robert, Košťál Vratislav, Vetchý David, Dvořáčková Kateřina

“…The main objective of this study was to evaluate the influence of the formulation and process parameters on PLGA microparticles containing a practically insoluble model drug (ibuprofen) prepared by the o/w solvent evaporation method. …”
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Retraction Note: Bone-targeting drug delivery system of biomineral-binding liposomes loaded with icariin enhances the treatment for osteoporosis by Xiaoduan Sun, Jun Wei, Jiayao Lyu, Tierong Bian, Zhongbing Liu, Juan Huang, Fengjuan Pi, Chunhong Li, Zhirong Zhong

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Antimicrobial Activity of <i>Zingiber Officinale</i> and <i>Allium Sativum</i> on some Drug Resistant Bacterial Isolates by S.E. Emmanuel, E.O. Ehinmitan, R.S. Bodunde, J.C. Joseph

“… Ginger and garlic are very important and useful spices and are used as therapeutic agent against many pathological infections. Increasing multi-drug resistance of pathogens forces researchers to find alternative compounds for treatment of infectious diseases. …”
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Analysis of the Thymidylate Synthase Gene Structure in Colorectal Cancer Patients and Its Possible Relation with the 5-Fluorouracil Drug Response by A. Calascibetta, Flavia Contino, S. Feo, G. Gulotta, M. Cajozzo, A. Antona, G. Sanguedolce, R. Sanguedolce

“…We planned to perform the whole TS gene structure by means of sequencing techniques in human colorectal cancer (CRC) samples to try to identify the presence of any possible TS variant form that could be responsible of fluoropyrimidines drug resistance and of the worse prognosis. …”
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PharmacoNER Tagger: a deep learning-based tool for automatically finding chemicals and drugs in Spanish medical texts by Jordi Armengol-Estapé, Felipe Soares, Montserrat Marimon, Martin Krallinger

“…The identification of drug mentions is also a prior step for complex event types such as drug dosage recognition, duration of medical treatments or drug repurposing. …”
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Improvement of the dissolution of the antineoplastic drug regorafenib through impregnation into pullulan polysaccharide using supercritical fluid technology: Optimization of the process by Ali Sheikhi, Sepideh Hamedi, Gholamhossein Sodeifian, Fariba Razmimanesh

“…The highest drug loading of 0.7 % was predicted by BBD under optimal conditions of 328 K, 280 bar, and 9 h. …”
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Determination of 5-fluorouracil anticancer drug solubility in supercritical CO 2 using semi-empirical and machine learning models by Gholamhossein Sodeifian, Ratna Surya Alwi, Reza Derakhsheshpour, Nedasadat Saadati Ardestani

Subjects: “…5-fluorouracil anti-cancer drug…”
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Application of Factorial and Doehlert Designs for the Optimization of the Simultaneous Separation and Determination of Antimigraine Drugs in Pharmaceutical Formulations by RP-HPLC-UV by Sami Jebali, Chaouki Belgacem, Mohamed Radhouen Louhaichi, Senda Bahri, Latifa Latrous El Atarche

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Risk Factors for Drug Resistance in Epileptic Children with Age of Onset above Five Years: A Case-Control Study by Irawan Mangunatmadja, Raden Muhammad Indra, Dwi Putro Widodo, Achmad Rafli

“…To identify risk factors for drug resistance in children with epilepsy with the age of onset above five years. …”
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Misuse of prescription medicines is as prevalent as the use of recreational drugs and novel psychoactive substances in Singapore: an unrecognised public health issue? by Wui Ling Chan, Paul Ivor Dargan, Colleen Michelle Haynes, Jody Lynn Green, Joshua Curtis Black, Richard Charles Dart, David Michael Wood

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Characterizing the Flow and Interaction of Microbubbles in a 2D Capillary Network for Targeted Drug Delivery: A Simulation Study by Sadegh Shurche, Akram Shahidani, Roghaye Bodaghi Hossein Abadi

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Evaluating programmatic reactive focal drug administration impact on malaria incidence in northern Senegal: an interrupted time series analysis by Ellen Leah Ferriss, Yakou Dieye, Moustapha Cissé, Gnagna Dieng Sow, Jean Louis Lankia, Damien Diedhiou, Abiboulaye Sall, Tamba Souane, Tidiane Thiam, Doudou Sene, Elhadji Doucouré, Ibrahima Diallo, Adam Bennett, Caterina Guinovart

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Electrooxidation and Development of a Highly Sensitive Electrochemical Probe for Trace Determination of the Steroid 11-Desoxycorticosterone Drug Residues in Water by Wejdan T. Alsaggaf, Mohammad S. El-Shahawi

“…The dependency of the anodic peak current of the CV at 0.4 V at various concentrations and scan rate of the DCS drug was characteristic of an electrode-coupled electron transfer of EE type mechanism. …”
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Co-Localized in Amyloid Plaques Cathepsin B as a Source of Peptide Analogs Potential Drug Candidates for Alzheimer’s Disease by Marilena K. Theodoropoulou, Konstantina D. Vraila, Nikos C. Papandreou, Georgia I. Nasi, Vassiliki A. Iconomidou

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Epidemiology of Multi-Drug Resistant Organisms in a Teaching Hospital in Oman: A One-Year Hospital-Based Study by Abdullah Balkhair, Yahya M. Al-Farsi, Zakariya Al-Muharrmi, Raiya Al-Rashdi, Mansoor Al-Jabri, Fatma Neilson, Sara S. Al-Adawi, Marah El-Beeli, Samir Al-Adawi

“…To describe the epidemiology of multi-drug resistant organisms (MDRO) at Sultan Qaboos University Hospital, a tertiary hospital in Oman. …”
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Factors Associated With Multi-Drug Resistant Organisms Among Bronchiectasis Patients: A Retrospective Study of Bronchiectasis Patients in Jordan by Al Oweidat K, Toubasi AA, Khraisat FA, Al-Sayegh TN, Al-Harasis LM, Albtoosh AS

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Design of Highly Adhesive Urchin‐Like Gold Nanostructures for Effective Topical Drug Administration and Symptomatic Relief of Corneal Dryness by Sandip Ghosh, Yun‐Han Su, Chia‐Jung Yang, Jui‐Yang Lai

“…Topical instillation of cyclosporin A (an anti‐inflammatory drug) is clinically recommended as the first‐line treatment for dry eye disease. …”
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