Drug response is related to NR3C1 and FAAH polymorphism in Chinese pediatric epilepsy patients by Hongli Wang, Chu Li, Qian Li, Ning Li, Huiling Qin

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HIV Drug Resistance-Associated Mutations in Antiretroviral Naïve HIV-1-Infected Latin American Children by Luis E. Soto-Ramirez, Roberto Rodriguez-Diaz, D. Robert Harris, Rohan Hazra

“…Our goal was to describe the presence of HIV drug resistance among HIV-1-infected, antiretroviral (ARV) naïve children and adolescents in Latin America and to examine resistance in these children in relation to drug exposure in the mother. …”
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Miniaturization and characterization of patient derived hepatocellular carcinoma tumor organoid cultures for cancer drug discovery applications by David A. Close, Paul A. Johnston

“…The ability to efficiently generate, expand, and biobank PDTOs has the potential to make the clinical diversity of cancer accessible for personalized medicine assay guided therapeutic drug selection and drug discovery. We describe the miniaturization and growth in 96- and 384-well formats of a single non-tumor liver and two Hepatocellular carcinoma (HCC) organoids derived from cryopreserved PDTO cells and the application of high content imaging (HCI) to characterize the models and enhance drug sensitivity testing. …”
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Development and Characterization of Chitosan Nanoparticles Loaded with Amoxicillin as Advanced Drug Delivery Systems against Streptococcus Mutans by Abdullah J Jasem, Maha A Mahmood

“… This study's primary objective was to create nanotechnology-based, precisely regulated drug delivery devices. Antibiotic Amoxicillin was chosen, and chitosan nanoparticles (CSNPs) were chosen to transport the medicine. …”
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Western Diet Decreases Hepatic Drug Metabolism in Male LDLr−/−ApoB100/100 Mice by Markus Koponen, Jaana Rysä, Anna-Kaisa Ruotsalainen, Olli Kärkkäinen, Risto O. Juvonen

“…Consequently, the WD may decrease the metabolic elimination of drugs compared to healthier low-fat diets.…”
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Multiple sclerosis: overview of orally administrated disease-modifying drugs. Do genetics influence the success of treatment? by A. Ovčinikova, R. Kizlaitienė

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Cytotoxicity of Nanocarrier-Based Drug Delivery in Oral Cancer Therapy: A Systematic Review and Meta-Analysis by Mohammad A. Saghiri PhD, Ravinder S. Saini PhD, Artak Heboyan PhD

“…Background Oral cancer remains 1 of the biggest health care challenges; it has a poor response to treatment, and treatment often results in severe side effects. Nano-targeted drug carrier-assisted drug delivery systems can improve the benefits of targeted drug delivery and treatment efficacy. …”
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An Innovative Drug Delivery System Loaded with a Modified Combination of Triple Antibiotics for Use in Endodontic Applications by Ardavan Parhizkar, Hanieh Nojehdehian, Fahimeh Tabatabaei, Saeed Asgary

“…The drug release from PPCMs was quantified by a UV spectrophotometer. …”
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Cereblon: A Protein Crucial to the Multiple Functions of Immunomodulatory Drugs as well as Cell Metabolism and Disease Generation by Qinglin Shi, Lijuan Chen

“…Studies have reported that it has an intermediary role in helping immunomodulatory drugs perform their immunomodulatory and tumoricidal effects. …”
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A pharmacological view on accounting for pharmacokinetic factors in the estimation of pharmaceutical emissions based on drug usage data by Frank Klont, J. Stein Bellinga, Valentina Giunchi, Spyros Balafas, Eelko Hak

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Investigation of Herb-Drug Interactions between Xylopia aethiopica, Its Principal Constituent Xylopic Acid, and Antidepressants by Christian C. Ndu, Wonder K. M. Abotsi, Priscilla K. Mante

“…One of the factors causing patients to not attain therapeutic goals is herb-drug interactions. Objective. To investigate any potential herb-drug interaction that might exist between Xylopia aethiopica extract (XAE) or xylopic acid (XA) and selected conventional antidepressants (imipramine, fluoxetine, and venlafaxine) in mice. …”
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Nosocomial Isolates and Their Drug Resistant Pattern in ICU Patients at National Institute of Neurological and Allied Sciences, Nepal by Pashupati Bhandari, Ganesh Thapa, Bharat Mani Pokhrel, Dwij Raj Bhatta, Upendra Devkota

“…This study was carried out from June 2011 to May 2012 at National Institute of Neurological and Allied Sciences Kathmandu, Nepal, with a view to determining drug resistant pathogens along with detection of extended spectrum β-lactamase (ESBL), AmpC β-lactamase (ABL), and metallo-β-lactamase (MBL) producing bacteria causing infection to ICU patients. …”
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Prevalence of Drug Resistance and Associated Mutations in a Population of HIV-1+ Puerto Ricans: 2006–2010 by Lycely del C. Sepúlveda-Torres, Alexandra De La Rosa, Luz Cumba, Nawal Boukli, Eddy Ríos-Olivares, Luis A. Cubano

“…This is a continuation of our efforts to maintain a record of the evolution of HIV-1 infection in Puerto Rico by monitoring the expression levels of antiretroviral drug-resistance-associated mutations. Samples from 2,500 patients from 2006–2010 were analyzed using the TruGene HIV-1 genotyping kit and the OpenGene DNA sequencing system. …”
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Multicentric Castleman's Disease in a Hepatitis C-Positive Intravenous Drug User: A Case Report by D. Y. Talukder, S. N. Delpachitra

“…A 46-year-old male with untreated hepatitis C and a 16-year history of intravenous drug use presented with pleuritic chest pain and bony pain in the knee, hip, and lower back, on a background of unexplained weight loss of 40 kilograms, fevers, night sweats, and repeated infections over the last two years. …”
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Biocompatibility and drug release kinetics of TiNbZrSn femtosecond laser-induced superhydrophilic structures by Tahir Nawaz, Vinod Paul, Sidrah Younus, Shahbaz Ahmad, Mehmet Egilmez, Wael Abuzaid, Ganjaboy Boltaev, Noor Akbar, Mustafa Khamis, Ghaleb A. Husseini, Ali S. Alnaser

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Overlapping of DRESS and Stevens-Johnson syndrome due to first-line antituberculosis drugs: a case report by Cristian Morán-Mariños, Felix Llanos-Tejada, Rebeca Huamani-Llantoy, Capriny Bernal-Turpo, Kimberly López-Pilco, Alex Ventura-Leon, Renato Casanova-Mendoza

“…Therapeutic Advances in Drug Safety…”
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Conductive polymers and derivatives as recognition element for electrochemical sensing of food and drug additives: A brief perspective by Hassan O. Shoyiga, Omolola E. Fayemi

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Hybrid optimal control for HIV multi-drug therapies: A finite set control transcription approach by Divya Thakur, Belinda Marchand

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Human PBMC-based humanized mice exhibit myositis features and serve as a drug evaluation model by Akiko Nishidate, Kana Takemoto, Yuki Imura, Mikako Murase, Ryu Yamanaka, Manami Kikuchi, Junpei Anan, Sayuka Kato, Airi Akatsuka, Sachiko Mochizuki, Yuzo Koda

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Modeling Drug Concentration Level in Blood Using Fractional Differential Equation Based on Psi-Caputo Derivative by Muath Awadalla, Yves Yannick Yameni Noupoue, Kinda Abu Asbeh, Noureddine Ghiloufi

“…This article studies a pharmacokinetics problem, which is the mathematical modeling of a drug concentration variation in human blood, starting from the injection time. …”
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