Update on Clinical Inflammometry for the Management of Airway Diseases by Parameswaran Nair

“…Judicious use of currently available drugs, such as corticosteroids, bronchodilators and antibiotics, and other anti-inflammatory therapies guided by sputum eosinophil and neutrophil counts, have been demonstrated to decrease exacerbations of asthma and chronic obstructive pulmonary disease, ameliorate cough, improve quality of life in patients with these diseases and is cost effective compared with treatment strategies based on guidelines that do not incorporate these measurements. …”
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Some statements on medical care in the "new normal" post-covid-19 by Alfredo Darío Espinosa Brito

“…This has been possible thanks to the joint efforts of the whole of society, with its highest authorities ahead, the capacity and dedication of health professionals organized in a vigorous national health system, obtaining and applying effective native drugs and the massive immunization against SARS-COV-2, with our Cuban Abdala and Soberanas vaccines. …”
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Long-Term Clinical Behavior of Jejunoileal Involvement in Crohn’s Disease by Hugh J Freeman

“…Moreover, pharmacological therapies with corticosteroids and immunosuppressant drugs were rarely successful, with virtually all patients requiring at least one, and usually multiple, intestinal resections. …”
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Treatment of neuro-invasive listeriosis: an overview by P. Gudeikaitė, J. Valaikienė, R. Mameniškienė

“…The most at-risk populations are pregnant women, neonates, people over 65 years of age, and patients with chronic diseases or using immunosuppressive drugs. In case of suspected acute meningitis, encephalitis or meningoencephalitis in these individuals, it must be considered that the pathogen can be Listeria monocytogenes, which is resistant to the therapy of cephalosporins. …”
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Antiretroviral therapies and status of people living with HIV in Japan: An update from hospital survey and national database. by Yoshiyuki Yokomaku, Tatsuya Noda, Mayumi Imahashi, Yuichi Nishioka, Tomoya Myojin, Aikichi Iwamoto, Tomoaki Imamura

“…A significant transition to single-tablet regimens and newer, highly effective antiretroviral drugs was observed, optimizing treatment adherence and outcomes. …”
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Unconventional Nuclides for Radiopharmaceuticals by Jason P. Holland, Matthew J. Williamson, Jason S. Lewis

“…This brief review describes the physical characteristics of 60 radionuclides, including β + , β −− , γ-ray, and α-particle emitters, which have the potential for use in the design and synthesis of the next generation of diagnostic and/or radiotherapeutic drugs. As the decay processes of many of the radionuclides described herein involve emission of high-energy γ-rays, relevant shielding and radiation safety issues are also considered. …”
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Pregnancy-Associated Sacroiliitis following an Uncomplicated Pregnancy by Maryam Ahmadi, Farid Abiri, Somaieh Ahmadiani, Ensiyeh Jenabi

“…Magnetic resonance imaging revealed little joint involvement, and the patient was treated with antibiotics, nonsteroidal anti-inflammatory drugs (NSAIDs), and glucocorticoids. The patient responded well to the therapy with marked improvement in her ambulation. …”
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Classification and Characteristics of Pain Associated with Parkinson’s Disease by Marcelo Rezende Young Blood, Marcelo Machado Ferro, Renato Puppi Munhoz, Hélio Afonso Ghizoni Teive, Carlos Henrique Ferreira Camargo

“…Its different clinical characteristics, variable relationship with motor symptoms, and inconsistent response to dopaminergic drugs suggest that the mechanism underlying pain in PD is complex and multifaceted, involving the peripheral nervous system, generation and amplification of pain by motor symptoms, and neurodegeneration of areas related to pain modulation. …”
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A select inhibitor of MORC2 encapsulated by chimeric membranecoated DNA nanocage target alleviation TNBC progression by Xiaohan Su, Yunbo Luo, Yali Wang, Peng Qu, Jun Liu, Shiqi Han, Cui Ma, Shishan Deng, Qi Liang, Xiaowei Qi, Panke Cheng, Lingmi Hou

“…Triple-negative breast cancer (TNBC) is the most malignant type of breast cancer and lacks effective targeted therapeutic drugs, resulting in a high recurrence rate and worse outcome. …”
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A Rare Case of Acute Renal Failure Secondary to Rhabdomyolysis Probably Induced by Donepezil by Osman Zikrullah Sahin, Teslime Ayaz, Suleyman Yuce, Fatih Sumer, Serap Baydur Sahin

“…The main etiologic factors are alcoholism, trauma, exercise overexertion, and drugs. In this report we present a rare case of ARF secondary to probably donepezil-induced rhabdomyolysis. …”
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Performance features of virus removal filters with novel regenerated cellulose hollow fiber membranes by Tomoko Hongo-Hirasaki, Hiroki Fukutomi

“…Technological advances in the development of new manufacturing technologies for continuous production and the development of next-generation antibody drugs have increased the need for virus removal filters suited to a variety of applications. …”
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GutBugDB: a web resource to predict the human gut microbiome-mediated biotransformation of biotic and xenobiotic molecules by Usha Longwani, Ashok K. Sharma, Aditya S. Malwe, Shubham K. Jaiswal, Vineet K. Sharma

“…It provides information on gut microbiome enzyme-mediated metabolic biotransformation for 1439 FDA-approved drugs and nutraceuticals. GutBugDB is publicly available at https://metabiosys.iiserb.ac.in/gutbugdb/.…”
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Complete pathway elucidation of echinacoside in Cistanche tubulosa and de novo biosynthesis of phenylethanoid glycosides by Wenqian Huang, Yaru Yan, Weisheng Tian, Xiaoxue Cui, Yingxia Wang, Yuelin Song, Ting Mo, Xiping Xu, Saijing Zhao, Yuyu Liu, Xiaohui Wang, Juan Wang, Yong Jiang, Jun Li, She-po Shi, Xiao Liu, Pengfei Tu

“…Abstract Echinacoside (ECH), one of the most representative phenylethanoid glycosides (PhGs), has considerable neuroprotective effects and is an effective ingredient in numerous commercial drugs. Here, we elucidate the complete ECH biosynthetic pathway in the medicinal plant Cistanche tubulosa. …”
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Biological treatment options for eosinophilic asthma, with consideration of markers of eosinophilic inflammation as predictors of treatment efficacy by Aleksandra Niemiec, Olga Branicka, Barbara Rymarczyk, Radosław Gawlik

“…These limitations prompted the development of targeted biological drugs that inhibit the mediators involved in T helper 2-inflammation, which is linked to the pathogenesis of asthma, such as interleukin 4, 5, 9, 13 and immunoglobulin E. …”
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Simultaneous RP HPLC Determination of Aceclofenac, Paracetamol and Tizanidine in Pharmaceutical Preparations by V. V. Vaidya, G. R. Singh, M. P. Choukekar, M. B. Kekare

“…Chromatographic separation of the three drugs were performed on a hypersil C18 column (250 mm x 4.6 mm, 5 µm) as stationary phase with a mobile phase comprising of mix phosphate buffer pH 7.0: acetonitrile (40:60 v/v), at a flow rate of 0.7 mL min-1 and UV detection at 230 nm. …”
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The effect of diclofenac on proliferation and production of growth factors by endothelial cells (HMEC-1) under hypoxia and inflammatory conditions by Wiktorowska-Owczarek Anna

“…Diclofenac belongs to non-steroidal anti-inflammatory drugs (NSAIDs) and non-selective COX inhibitors. …”
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Carotidynia: A Rare Diagnosis for Unilateral Neck Pain Revealed by Cross-Sectional Imaging by Corrado Santarosa, Salvatore Stefanelli, Roman Sztajzel, Pravin Mundada, Minerva Becker

“…The patient was treated with nonsteroidal anti-inflammatory drugs and symptoms and imaging findings disappeared within a few weeks. …”
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Evaluation of the Efficacy of Nasal Sedation Midazolam Compared with Dexmedetomidine in the Management of Uncooperative Children with Down Syndrome during Dental Treatment by Mohamad Nabil Hamod, Chaza Kouchaji, Faten Rostom, Hasan Alzoubi, Imad Katbeh, Nikolay Tuturov

“…The efficacy of both the drugs was evaluated according to Ohio State University Behavioral Rating Scale (OSUBRS), University of Michigan scale (UMSS), and Houpt general behavior scale. …”
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Mathematical modeling of liver fibrosis by Avner Friedman, Wenrui Hao

“…We use the model to explore the efficacy of potential and currently used drugs aimed at blocking the progression of liver fibrosis. …”
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Hyperkalemia Induced Brugada Phenocopy: A Rare ECG Manifestation by Muhammad Ameen, Ghulam Akbar, Naeem Abbas, Ghazi Mirrani

“…Various electrolyte disturbances and ion channels blocking drugs could also provoke BrS ECG findings without genetic BrS. …”
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