Phytochemical Screening of the Roots, Stem, Leaves and Flowers of Tithonia Diversifolia For Antimicrobial Properties. by Baluku, Geoffrey Kapere

“…Plants are the most available sources of nutrients and phytochemicals, which have played an important role in the development of drugs and treatment of various ailments. Therefore, this study was carried to ascertain the phytochemical classes of the bioactive compounds from the leaves, flowers, stems, and roots of Tithonia diversifolia and their antimicrobial activity. …”
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Cytokines in Thyroid-Associated Ophthalmopathy by Pengbo Zhang, Huang Zhu

“…In recent years, cytokines and the immune responses they mediate have been crucial in disease progression, and currently, common evidence has shown that drugs targeting cytokines, such as tocilizumab, infliximab, and adalimumab, may be novel targets for therapy. …”
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Comparative analysis of lactaptin activity when produced in bacterial or eukaryotic expression systems by O. A. Koval, O. Y. Volkova, A. A. Gorchakov, S. V. Kulemzin, A. V. Tkachenko, A. A. Nushtaeva, E. V. Kuligina, V. A. Richter, A. V. Taranin

“…Despite the multitude of anticancer cytostatic drugs available to oncologists today, most of such drugs have serious side effects that may preclude their use in some groups of patients. …”
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Treatable traits in idiopathic pulmonary fibrosis: focus on respiratory tract infections—a systematic review and a meta-analysisResearch in context by Zsombor Matics, Anna Bardóczi, Csongor Galkó, Bence Szabó, Noémi Gede, Zsolt Molnár, Gábor Duray, Caner Turan, Péter Hegyi, Gábor Horváth, Veronika Müller

“…Only randomized controlled trials of drugs intended for IPF treatment in adults and reporting RTI incidence were included. …”
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Generation and characterization of two induced pluripotent stem cell lines (ICGi052-A and ICGi052-B) from a patient with frontotemporal dementia with parkinsonism-17 associated wit... by E. V. Grigor’eva, A. A. Malakhova, E. S. Yarkova, J. M. Minina, Y. V. Vyatkin, J. A. Nadtochy, E. A. Khabarova, J. A. Rzaev, S. P. Medvedev, S. M. Zakian

“…The iPSC lines obtained and characterised in detail in this work represent a unique tool for studying the molecular genetic mechanisms of the pathogenesis of frontotemporal dementia with parkinsonism-17, as well as for testing potential drugs in vitro.…”
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Assessment of prognosis and responsiveness to immunotherapy in colorectal cancer patients based on the level of immune cell infiltration by Kaili Liao, Minqi Zhu, Lei Guo, Zijun Gao, Jinting Cheng, Bing Sun, Yihui Qian, Bingying Lin, Jingyan Zhang, Tingyi Qian, Yixin Jiang, Yanmei Xu, Qionghui Zhong, Xiaozhong Wang

“…And the chemotherapeutic response to different drugs was assessed.ResultsWe established a novel prognostic model utilizing the WGCNA method, which demonstrated robust predictive accuracy for patient survival. …”
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Global outcomes and prognosis for relapsed/refractory mature T-cell and NK-cell lymphomas: results from the PETAL consortium by Jessy Xinyi Han, Min Jung Koh, Leora Boussi, Mark Sorial, Sean M. McCabe, Luke Peng, Shambhavi Singh, Ijeoma Julie Eche-Ugwu, Judith Gabler, Maria J. Fernandez Turizo, Caroline T. MacVicar, Aditya Garg, Alexander Disciullo, Kusha Chopra, Alexandra Lenart, Emmanuel Nwodo, Jeffrey Barnes, Min Ji Koh, Eliana Miranda, Carlos Chiattone, Robert Stuver, Steven M. Horwitz, Mwanasha Merrill, Eric Jacobsen, Martina Manni, Monica Civallero, Tetiana Skrypets, Athina Lymboussaki, Massimo Federico, Yuri Kim, Jin Seok Kim, Jae Yong Cho, Thomas Eipe, Tanuja Shet, Epari Sridhar, Alok Shetty, Saswata Saha, Hasmukh Jain, Manju Sengar, Carrie Van Der Weyden, Henry Miles Prince, Ramzi Hamouche, Tinatin Murdashvili, Francine Foss, Marianna Gentilini, Beatrice Casadei, Pier Luigi Zinzani, Takeshi Okatani, Noriaki Yoshida, Sang Eun Yoon, Won-Seog Kim, Girisha Panchoo, Zainab Mohamed, Estelle Verburgh, Jackielyn Cuenca Alturas, Mubarak Al-Mansour, Josie Ford, Maria Elena Cabrera, Amy Ku, Govind Bhagat, Helen Ma, Ahmed Sawas, Khyati Maulik Kariya, Makoto Iwasaki, Forum Bhanushali, Owen A. O’Connor, Enrica Marchi, Changyu Shen, Devavrat Shah, Salvia Jain

“…Abstract: Variances in global access to drugs and treatment practices make it challenging to understand the benefit of contemporary therapies in patients with relapsed and refractory (R/R) mature T-cell and natural killer–cell lymphomas (MTCL and MNKCL). …”
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Mental health apps in India: regulatory landscape and future directions by M. I. Singh Sethi, Rakesh C. Kumar, Narayana Manjunatha, Channaveerachari Naveen Kumar, Suresh Bada Math

“…India's framework, including the Central Drugs Standard Control Organization (CDSCO) and Medical Device Rules 2017, does not cover standalone health apps, raising concerns about data privacy and accuracy. …”
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Hippocampal Neurogenesis, Depressive Disorders, and Antidepressant Therapy by Eleni Paizanis, Michel Hamon, Laurence Lanfumey

“…In particular, the stimulation of hippocampal neurogenesis by all types of antidepressant drugs supports the view that neuroplastic phenomena are involved in the physiopathology of depression and underlie—at least partly—antidepressant therapy.…”
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Antimony Resistance in Leishmania, Focusing on Experimental Research by Fakhri Jeddi, Renaud Piarroux, Charles Mary

“…However, resistance toward these compounds has recently emerged in areas where the replacement of these drugs is mainly limited by the cost of alternative molecules. …”
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On Topological Indices of Fractal and Cayley Tree Type Dendrimers by Muhammad Imran, Abdul Qudair Baig, Waqas Khalid

“…These descriptors are studied and used in mathematical chemistry, medicines, and drugs designs and in other areas of applied sciences. …”
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Possible Relevance of Receptor-Receptor Interactions between Viral- and Host-Coded Receptors for Viral-Induced Disease by Luigi F. Agnati, Giuseppina Leo, Susanna Genedani, Diego Guidolin, Nicola Andreoli, Kjell Fuxe

“…The prevention of viral receptor-induced changes in host receptor networks may give rise to novel antiviral drugs that counteract viral-induced disease.…”
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Pain Mechanism in Rheumatoid Arthritis: From Cytokines to Central Sensitization by Yanting Cao, Danping Fan, Yiqing Yin

“…Although in recent years, through the implementation of targeted treatment and the introduction of disease-modifying antirheumatic drugs (DMARDs), the treatment of RA patients has made a significant progress, a large proportion of patients still feel pain. …”
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PPARγ and PPARδ as Modulators of Neoplasia and Cell Fate by Robert I. Glazer, Hongyan Yuan, Zhihui Xie, Yuzhi Yin

“…PPARγ and PPARδ agonists represent unique classes of drugs that act through their ability to modulate gene transcription associated with intermediary metabolism, differentiation, tumor suppression, and in some instances proliferation and cell adhesion. …”
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Synthesis and Characterization of Oxozirconium(IV), Dioxomolybdenum(VI) and Dioxotungsten(VI) with Ciprofloxacin and Norfloxacin Complexes by Khalaf I. Khallow, Amaal Y. R. Al-Assaf

“…The interaction of quinolone drugs, ciprofloxacin (CIPH) and norfloxacin (NORH), with zirconyl chloride octahydrate, sodium molybdate dihydrate and sodium tungstate dihydrate was investigated. …”
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Annoying Hiccups following Intra-Articular Corticosteroid Injection of Betamethasone Acetate/Betamethasone Sodium Phosphate at the Knee Joint by George Habib, Suheil Artul, Geries Hakim

“…Hiccups is a type of reflex that could happen secondary to different causes including drugs, especially systemic corticosteroids. Usually, high rather than regular doses of systemic steroids are incriminated, and this could explain the fact that very few cases of hiccups following regional corticosteroid treatment were reported. …”
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Asymmetric Dimethyl Arginine as a Biomarker of Atherosclerosis in Rheumatoid Arthritis by Manuela Di Franco, Bruno Lucchino, Fabrizio Conti, Guido Valesini, Francesca Romana Spinelli

“…Despite the advent on new drugs targeting the articular manifestations, the burden of cardiovascular disease is still an unmet need in the management of RA. …”
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The Crosstalk between Myeloid Derived Suppressor Cells and Immune Cells: To Establish Immune Tolerance in Transplantation by Chao Zhang, Shuo Wang, Cheng Yang, Ruiming Rong

“…Considering their strong immunosuppressive capability, MDSCs could become a prospective clinical regimen during transplantation tolerance induction, resulting in long-term graft survival with decreased or without immunosuppressive drugs. The review summarized recent research advances in this field and looked ahead at the research directions in the future.…”
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Synthesis, Spectral and Anthelmintic Activity Studies on Some Novel Imidazole Derivatives by Rajiv Dahiya, Anil Kumar

“…Synthesized imidazolopeptides were screened for their anthelmintic activity and found to possess moderate to good bioactivity against earthworms Megascoplex konkanensis, Pontoscotex corethruses and Eudrilus eugeniea when compared to reference drugs - albendazole and mebendazole at dose level of 2 mg mL−1.…”
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Atypical Kaposi Sarcoma of the Tongue in HIV Positive Tanzanian Female by Elichilia Shao, Flora Ruhangisa, Neema Minja, Kanankira Nnko, Denis Katundu, George Semango, Eva Mbwilo, Amos Mwasamwaja, Kajiru Kilonzo, Isaack Lyaruu

“…This patient was newly diagnosed and had no history of antiretroviral therapy (ART), radiotherapy, or immunosuppressive drugs prior to this admission. Clinically, there were no dermatological features of KS lesions which are purple, red, or brown and which may be flat, raised (plaques), or bumpy (nodules) except for fungating and protruding enlarged tongue which was necrotic. …”
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