Molecular Mechanisms of Breast Cancer Drug Resistance and CRISPR/Cas9 Strategies to Overcome by Bashdar Mahmud Hussen, Bnar Saleh Ismael, Saman S. Abdulla, Noor Haval Jamal, Suhad Asad Mustafa, Zana Baqi Najmalddin, Mohammed Fatih Rasul

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Pharmacological and Pharmacodynamic Implications of Nonsteroidal Anti-Inflammatory Drug Therapy in Elderly Arthritic Patients by W Watson Buchanan

“…There is growing evidence chat elderly patients may be more likely to develop adverse drug reactions to nonsteroidal anti-inflammatory drug/analgesic therapy. …”
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Machine Learning-Assisted Drug Repurposing Framework for Discovery of Aurora Kinase B Inhibitors by George Nicolae Daniel Ion, George Mihai Nitulescu, Dragos Paul Mihai

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A model of competing saturable kinetic processes with application to thepharmacokinetics of the anticancer drug paclitaxel by Rebeccah E. Marsh, Jack A. Tuszyński, Michael Sawyer, Kenneth J. E. Vos

“…A saturable multi-compartment pharmacokinetic model for the anti-cancer drug paclitaxel is proposed based on a meta-analysis of pharmacokinetic data published over the last two decades. …”
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A multistage drug delivery approach for colorectal primary tumors and lymph node metastases by Yihang Yuan, Quanjun Lin, Hai-Yi Feng, Yunpeng Zhang, Xing Lai, Mao-Hua Zhu, Jue Wang, Jiangpei Shi, Yanhu Huang, Lele Zhang, Qin Lu, Zeli Yuan, Jonathan F. Lovell, Hong-Zhuan Chen, Peng Sun, Chao Fang

“…Taken together, this study demonstrates a deliberate treatment approach for management of both primary tumors and metastatic LNs through multistage drug delivery.…”
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Statin drugs enhance responses to immune checkpoint blockade in head and neck cancer models by Chrystal Paulos, Gregory B Lesinski, Zachary S Buchwald, Nabil F Saba, Vikash Kansal, Andre J Burnham, Brendan L C Kinney, Nicole C Schmitt

“…Background Anti-PD-1 immune checkpoint blockade is approved for first-line treatment of recurrent/metastatic head and neck squamous cell carcinoma (HNSCC), but few patients respond. Statin drugs (HMG-CoA reductase inhibitors) are associated with superior survival in several cancer types, including HNSCC. …”
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Potentiometric Multisensory Systems with Novel Ion-Exchange Polymer-Based Sensors for Analysis of Drugs by Olga V. Bobreshova, Anna V. Parshina, Ksenia A. Polumestnaya

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Localized Drug Delivery in Different Gastrointestinal Cancers: Navigating Challenges and Advancing Nanotechnological Solutions by Hasan AM, Cavalu S, Kira AY, Hamad RS, Abdel-Reheim MA, Elmorsy EA, El-kott AF, Morsy K, AlSheri AS, Negm S, Saber S

“…To overcome these obstacles, nano-drug delivery systems (NDDs) have been designed and proved their potential by exploiting these challenges in favor of offering a specific delivery to the desired target. …”
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Drug-target binding affinity prediction based on power graph and word2vec by Jing Hu, Shuo Hu, Minghao Xia, Kangxing Zheng, Xiaolong Zhang

Subjects: “…Drug-target affinity…”
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Ferroptosis and pyroptosis are connected through autophagy: a new perspective of overcoming drug resistance by Peng Zhao, Shuangshuang Yin, Yuling Qiu, Changgang Sun, Haiyang Yu

“…Abstract Drug resistance is a common challenge in clinical tumor treatment. …”
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Adaptation of Color Reactions for Spectrophotometric Determination of Pitavastatin Calcium in Bulk Drugs and in Pharmaceutical Formulations by Marothu Vamsi Krishna, Dannana Gowri Sankar

“…Three simple, sensitive and cost effective Spectrophotometric methods are described for the determination of pitavastatin calcium (PST) in bulk drugs and in pharmaceutical formulations. These methods are based on the oxidation of PST by ferric chloride in presence of o-phenanthroline (Method A) or 2, 2’ bipyridyl (Method B) or potassium ferricyanide (Method C). …”
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A Lethal Complication after Transarterial Chemoembolization with Drug-Eluting Beads for Hepatocellular Carcinoma by Adriana Toro, Gaetano Bertino, Maria Concetta Arcerito, Maurizio Mannnino, Annalisa Ardiri, Domenico Patane’, Isidoro Di Carlo

“…TACE may also be performed with drug-eluting beads, but serious complications of this procedure have been reported. …”
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Nonlinearities in Drug Release Process from Polymeric Microparticles: Long-Time-Scale Behaviour by Elena Simona Bacaita, Costica Bejinariu, Borsos Zoltan, Catalina Peptu, Gabriela Andrei, Marcel Popa, Daniela Magop, Maricel Agop

“…A theoretical model of the drug release process from polymeric microparticles (a particular type of polymer matrix), through dispersive fractal approximation of motion, is built. …”
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Theoretical assessment of the relative incidences of sensitive andresistant tuberculosis epidemic in presence of drug treatment by Silvia Martorano Raimundo, Hyun Mo Yang, Ezio Venturino

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Proficiency Testing of Drug Susceptibility Results in the Canadian Network of Public Health TB Laboratories by A Laszlo, National Tuberculosis Laboratory Network

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Pharmacogenetic markers of colorectal cancer treatment. New approaches for cytostatic drugs efficacy estimation by N. B. Zakharzhevskaya, N. A. Kulemin, Ye. A. Babikova, Ye. B. Khomyakova, E. V. Generozov

“…If efficacy and necessity of pharmacogenetic investigation for such drugs of targeted therapy, as cetuximab, is already proven for the present time, it is still underestimated for the widely applied drugs of general cytostatic action. …”
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Mathematical Modeling and Optimal Control Strategy for a Discrete Time Drug Consumption Model by Abderrahim Labzai, Abdelfatah Kouidere, Bouchaib Khajji, Omar Balatif, Mostafa Rachik

“…The aim of this paper is to study and investigate the optimal control strategy of a discrete mathematical model of drug consumption. The population that we are going to study is divided into six compartments: potential drug users, light drug users, heavy drug users, heavy drug users-dealers and providers, temporary quitters of drug consumption, and permanent quitters of drug consumption. …”
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3-Methyl-4-Nitrobenzoate Derivates as Antifungal Drug Candidates: Biological and In Silico Evaluation by Alana R. Ferreira, Yunierkis P. Castillo, Ana C. M. Andrade, Diego F. Nóbrega, João Paulo G. de Oliveira, Tamires C. Lima, Ricardo D. de Castro, Damião P. de Sousa

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Leflunomide induced drug reaction with eosinophilia and systemic symptoms: A lesser known entity by Deepak Vashisht, Madhab Durga Tripathy, Sunmeet Sandhu, Rohit Kothari, Surbhi Vashisht, Arun Hegde

Subjects: “…drug reaction with eosinophilia and systemic symptoms…”
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Transoral Drug-Induced Sleep Endoscopy: A Useful Complementary Tool in Sleep Surgery by Ahmed Elsobki, Mohammed Elshaer, Hassan Ghabn, Mohamed E. El-deeb, Luci Suliman

“… Introduction Drug-induced sleep endoscopy (DISE) is performed widely, and several studies have demonstrated its validity as it provides clinical information not available by routine clinical inspection alone.…”
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