New trends in the treatment of androgenetic alopecia by Szymon Leonik, Michał Smoczok, Beata Bergler-Czop

“…However, treatments with proven efficacy approved by recognised organisations and associations are limited, and research is ongoing to discover new drugs, redesign existing ones and establish therapy algorithms. …”
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Invasive Heart Rate Control as a Salvage Therapy in Amiodarone-induced Thyroid Storm by Emin Evren OZCAN, Mustafa DOGDUS, Resit Yigit YILANCIOGLU, Suleyman Cem ADIYAMAN, Oguzhan Ekrem TURAN

“…Atrial fibrillation (AF) is the most common arrhythmia, and amiodarone is one of the most commonly used drugs for medical cardioversion of AF, which should be used carefully due to its toxic effects. …”
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Cerebral Wegener’s Granuloma: Surgery Mandatory for Diagnosis and Treatment by Federico Nicolosi, Giovanni Nodari, Giannantonio Spena, Elena Roca, Karol Migliorati, Giacomo Esposito, Roberto Stefini, Marco Fontanella, Pier Paolo Panciani

“…The importance of a surgery in case of localized WG has been emphasized, in order to confirm the diagnosis and to avoid additional medicaments, like antiepileptic drugs, potentially harmful in immunosuppressed patients.…”
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Genotoxic consequences of viral infections by Olga Szewczyk-Roszczenko, Piotr Roszczenko, Yegor Vassetzky, Nikolajs Sjakste

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Usage and cost-effectiveness of anti-psychotics in psychiatry OPD among various clinical conditions: A prospective observational study in a tertiary care center by Reshabh Saini, Chandrasekaran Dhinakaran, Rohit Raina, Ramanathan Gandhibabu, Kathiresan Krishnasamy

“…Background: Psychotropic medications are prescription drugs that are commonly used to control some symptoms associated with many different types of mental ill health. …”
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Discrete choice modelling of hypertension patients’ preferences for attributes of a public medical facility in Ibadan, Nigeria by Oluwaseun Aramide Otekunrin, Tekiyat Abiola Adebisi, Sururoh Adeniran-Babatunde, Olutosin Ademola Otekunrin

“…The patients were unwilling to pay for the “little or no drugs and diagnostic equipment” attribute level. …”
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Druggability and molecular docking of essential secondary metabolites from Azadirachta indica leaf against angiotensin converting enzyme-2: Covid-19 in focus by Paul Chijioke Ozioko, Ukamaka Owohetete, Daniel Danladi Gaiya

“…Of the 12 secondary metabolites from A. indica and 5 FDA-approved drugs identified, azadirachtin A, azadirachtin D, azadirachtin H, azadirachtin F, azadirachtin I and nimbolin, and ivermectin showed relatively poor druggability. …”
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<i>Alaria esculenta, Ulva lactuca</i>, and <i>Palmaria palmata</i> as Potential Functional Food Ingredients for the Management of Metabolic Syndrome by Emer Shannon, Maria Hayes

“…In vitro enzyme inhibitory assays were used to quantify the bioactivity of the seaweed extracts and compare their half-maximal inhibitory (IC₅₀) values to recognised positive control enzyme inhibitory drugs captopril© (an ACE-1 inhibitor), acarbose (an α-amylase inhibitor), and orlistat (a lipase inhibitor). …”
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Impact of topical cetylated fatty acid cream on hand osteoarthritis: a randomized, double-blind clinical trial by Sitthiphong Suwannaphisit, Nitiphoom Sinnathakorn, Pormes Suwanno, Warangkana Fongsri, Boonsin Tangtrakulwanich

“…Abstract In addition to topical non-steroidal anti-inflammatory drugs that are used in hand osteoarthritis, there are other drugs that can reduce pain in osteoarthritis, such as topical cetylated fatty acids. …”
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Antiviral and anti-inflammatory activities of favipiravir and quinine sulfate against dengue virus serotype 1 in vitro by Regita Aulia Rosalina, Beti Ernawati Dewi, Fithriyah Fithriyah

“…Meanwhile, the use of anti-inflammatory drugs for DENV is limited to patients with severe clinical symptoms. …”
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mRNA technology as one of the promising platforms for the SARS-CoV-2 vaccine development by A. A. Ilyichev, L. A. Orlova, S. V. Sharabrin, L. I. Karpenko

“…Until recent years, mRNA-vaccination was out of practical implementation due to high sensitivity to nuclease degradation and consequent instability of drugs based on mRNA. Latest technological advances significantly mitigated the problems of low immunogenicity, instability, and difficulties in RNA-vaccine delivery. …”
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Activities of Some Medicinal Plants on the Proliferation and Invasion of Brain Tumor Cell Lines by Saidu I. Ngulde, Umar K. Sandabe, Roger Abounader, Ying Zhang, Isa M. Hussaini

“…Plants have been the major source of anticancer drugs both in orthodox and traditional medicine. …”
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Update on Pulmonary Toxicity Induced by New Breast Cancer Treatments by Belluzzi L, Martinelli G, Medici B, Farina A, Martinelli E, Canino F, Caggia F, Molinaro A, Barbolini M, Tamburrano F, Moscetti L, Piacentini F, Dominici M, Omarini C

“…We conducted an update including the available published data regarding the incidence, mechanisms of pathogenesis, clinical presentations, and treatment of lung toxicity induced by new anticancer drugs. A literature search was performed between January and June 2024, considering papers, clinical trials, case reports, case series, meta-analyses, and systematic reviews published from January 2014 to June 2024. …”
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The Effect of Mesenchymal Stem Cell-Derived Exosomes and miR17-5p Inhibitor on Multicellular Liver Fibrosis Microtissues by Farnaz Sani, Mina Soufi Zomorrod, Negar Azarpira, Masoud Soleimani

“…Therefore, we propose this novel MLM model to understand fibrosis mechanisms better and develop new drugs.…”
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Constructing a fall risk prediction model for hospitalized patients using machine learning by Cheng-Wei Kang, Zhao-Kui Yan, Jia-Liang Tian, Xiao-Bing Pu, Li-Xue Wu

“…Results The final model included the following variables: Adl_standing, Adl_evacuation, Age_group, Planned_surgery, Wheelchair, History_of_falls, Hypnotic_drugs, Psychotropic_drugs, and Remote_caring_system. …”
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Empagliflozin-Metformin Combination Has Antioxidative and Anti-Inflammatory Properties that Correlate with Vascular Protection in Adults with Type 1 Diabetes by Miodrag Janić, Matej Cankar, Jan Šmid, Alenka France Štiglic, Aleš Jerin, Mišo Šabovič, Andrej Janež, Mojca Lunder

“…In the present study, we explored the underlying mechanism by investigating the antioxidative and anti-inflammatory properties of the empagliflozin-metformin combination (compared to the individual drugs or placebo) and its association with improving arterial function. …”
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Systematic review of innate immune responses against Mycobacterium tuberculosis complex infection in animal models by Luisa Maria Nieto Ramirez, Carolina Mehaffy, Karen Marie Dobos

“…Results were categorized in four groups: MTBC species, animal models, soluble factors and innate pathways, and other molecules (metabolites and drugs). Mtb and M. bovis were the only species studied. …”
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Clinical Characteristics of COVID-19 Patients with and without Diabetes in Wuhan Red Cross Hospital by Guozhen Li, Qin Deng, Jiali Feng, Fang Li, Nian Xiong, Qiong He

“…The cases were divided into the diabetic and nondiabetic groups according to the history of taking antidiabetic drugs or by plasma fasting blood glucose level at admission, and the differences between the groups were compared. …”
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Pulmonary Disease due to Mycobacterium malmoense in British Columbia by Mohamed S Al-Moamary, William Black, Kevin Elwood

“…This report describes a case of pulmonary disease caused by M malmoense in a 44-year-old man from British Columbia who was successfully treated with an 18-month course of conventional antituberculous drugs combined with a macrolide. This is the first report of this disease in British Columbia and, to our knowledge, in Canada.…”
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Caffeic Acid Phenethyl Ester as a Protective Agent against Nephrotoxicity and/or Oxidative Kidney Damage: A Detailed Systematic Review by Sumeyya Akyol, Veli Ugurcu, Aynur Altuntas, Rukiye Hasgul, Ozlem Cakmak, Omer Akyol

“…One of the most studied organs for the effects of CAPE is the kidney, particularly in the capacity of this ester to decrease the nephrotoxicity induced by several drugs and the oxidative injury after ischemia/reperfusion (I/R). …”
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