Is otologic surgery contributing to the opioid epidemic? by Valerie Dahm, Justin T. Lui, Rudolfs Liepins, Joseph M. Chen, Trung N. Le, Christoph Arnoldner, Vincent Y. W. Lin

“…Some of the prescribed drugs by European otologists are not available in North America. …”
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Efficient Acquisition of Fully Human Antibody Genes against Self-Proteins by Sorting Single B Cells Stimulated with Vaccines Based on Nitrated T Helper Cell Epitopes by Liangliang Jiang, Tao Jiang, Jianhua Luo, Yanliang Kang, Yue Tong, Xiaoda Song, Xiangdong Gao, Wenbing Yao, Hong Tian

“…Single B cell antibody technology is a method for isolating antigen-specific B cells from human peripheral blood and obtaining antibody genes in developing antibody drugs. However, owing to immune tolerance to autoantigen, human autoantigen-specific B cells are difficult to acquire by conventional single B cell technology. …”
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Evaluation of Melongosides as Potential Inhibitors of NS2B-NS3 Activator-Protease of Dengue Virus (Serotype 2) by Using Molecular Docking and Dynamics Simulation Approach by Partha Biswas, Ommay Hany Rumi, Dhrubo Ahmed Khan, Md Nasir Ahmed, Nusratun Nahar, Rownak Jahan, Md Nazmul Hasan Zilani, Tridib K Paul, Anamul Hasan, Tohmina Afroze Bondhon, Khoshnur Jannat, Md Nazmul Hasan, Mohammed Rahmatullah

“…Dengue has no available drugs for treatment; CYD-TDV is the only vaccine thus far approved for use by a few countries in the world. …”
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S-Amlodipine: An Isomer with Difference—Time to Shift from Racemic Amlodipine by Jamshed Dalal, J. C. Mohan, S. S. Iyengar, Jagdish Hiremath, Immaneni Sathyamurthy, Sandeep Bansal, Dhiman Kahali, Arup Dasbiswas

“…Calcium channel blockers are among the first-line drugs for treatment of hypertension (HTN). S-amlodipine (S-AM), an S-enantiomer of amlodipine, is available in India and in other countries like China, Korea, Russia, Ukraine, and Nepal. …”
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Peroxisome Proliferator-Activated Receptors (PPARs) as Potential Inducers of Antineoplastic Effects in CNS Tumors by Lars Tatenhorst, Eric Hahnen, Michael T. Heneka

“…Remarkably, studies examining the effects of these drugs in vivo are just beginning to emerge. However, the agonists of PPARs, in particular the thiazolidinediones, seem to be promising candidates for new approaches in human CNS tumor therapy.…”
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Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis by Jeanneth Elizabeth Jami Carrera, John Sebastián Carvajal Gavilanes, Karen Gabriela Sulca Espín, Dennis Alexander Montenegro Montenegro

“…Stevens-Johnson syndrome and toxic epidermal necrolysis are severe mucocutaneous rare diseases with high morbid mortality characterized by generalized epidermal necrosis and skin detachment; They are distinguished from each other due to the extent of skin that is affected. Drugs are the main trigger factor, usually in the first weeks of treatment. …”
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The Rising of “Modern Actinobacteria” Era by Jodi Woan-Fei Law, Vengadesh Letchumanan, Loh Teng-Hern Tan, Hooi-Leng Ser, Bey-Hing Goh, Learn-Han Lee

“…MOD-ACTINO is defined as a group of actinobacteria capable of producing compounds that can be explored for modern applications such as development of new drugs and cosmeceutics. MOD-ACTINO members consist of already identified or novel actinobacteria isolated from special environments: mangrove, desert, lake, hot spring, cave, mountain, Arctic and Antarctic regions. …”
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The Functions of PPARs in Aging and Longevity by Adnan Erol

“…PPARs are important redox-sensitive transcription factors and their dyregulated activations seem to be major culprits for these pathological processes. Drugs targeting PPARs activity are already in widespread clinical use; however, based on these concepts, this review highlights the understanding of the role of PPARs in aging and indicates the necessary particular attention for the potential therapeutic uses of current PPAR agonists in age-associated diseases.…”
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COVID-19: An Emerging Culprit of Inflammatory Arthritis by Muhammad Shariq Mukarram, Muhammad Ishaq Ghauri, Sehrish Sethar, Nasir Afsar, Amir Riaz, Khizra Ishaq

“…These patients were treated successfully with low-dose glucocorticoids and disease-modifying antirheumatic drugs (DMARDs).…”
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Pregnancy counseling in rheumatic diseases: Where science meets the steps by Anu Balakrishnan, Pankti Mehta, Latika Gupta

“…Most rheumatic diseases (RDs) have a predilection for women in the reproductive age group. Common drugs used in rheumatology practice have identified risks to the fetus; thus, adequate pregnancy counseling is of utmost importance. …”
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Thyroid Hemiagenesis Associated with Hashimoto’s Thyroiditis by D. Nsame, A. Chadli, L. Hallab, S. El Aziz, H. El Ghomari, A. Farouqi

“…We report a 23-year-old female presented with Hashimoto’s thyroiditis in left lobe, associated with hemiagenesis of right lobe and isthmus which was previously diagnosed as Graves’ hyperthyroidism, but developed further into Hashimoto’s thyroiditis after being treated with antithyroid drugs. The symptoms of hyperthyroidism in the current case led to the diagnostic confirmation by scintiscanning of an absent lobe. …”
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The Positive Effect of Psychotherapy in the Treatment of an Erosive Oral and Dermal Lichen Planus Case by Zana Fuad Noori, Mohammed Khalid Mahmood, Pinar Yaseen Raof, Handren Ameer Kurda, Balen Hamid Qadir, Didar Anwar Abdulrahman, Mohammed Aso Abdulghafor, Mohammed Taib Fatih, Basoz Khalid Hama Noori

“…Due to this apparent comorbidity and the risk of not responding well to conventional medication (topical and systemic corticosteroids) or the risk of relapse in the case of ongoing stress, we decided to integrate psychotherapy (without psychotropic drugs) as an adjunct into the management strategy. …”
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Connections and Unmet Needs: Severe Asthma Biologics and Osteoporosis by Fabiana Furci, Marco Umberto Scaramozzino, Giuseppe Rocco Talesa, Corrado Pelaia

“…Asthma is a chronic inflammatory disease with the main anti-inflammatory drugs for better disease control being steroids or corticosteroids. …”
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Pseudopheochromocytoma Associated with Domestic Assault by H. M. Le, G. Carbutti, D. Ilisei, E. Bouccin, X. Vandemergel

“…Treatment of pseudopheochromocytoma can be challenging due to normal blood pressure values in between the hypertensive peaks; it includes alpha- and beta-blockers for moderate crises and prevention and must be combined with psychopharmacologic agents such as anxiolytics or antidepressant drugs. Psychotherapy and dietetic treatment are also crucial in pseudopheochromocytoma management.…”
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Hypercalcemic Crisis in a Patient with Post-Surgical Hypoparathyroidism by Wannita Tingsarat, Chalermchai Lertanasit, Jaruwan Kongkit, Thiti Snabboon

“…To diagnose CAS it requires a high index of suspicion and a detailed history of medication/supplement intake specifically for calcium-containing drugs and a history of all possible ingested alkali. …”
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Neuroleptic Malignant Syndrome: Diagnostic and Therapeutic Dilemmas by Abebaw Fekadu, Jonathan I. Bisson

“…Neuroleptic malignant syndrome (NMS) is a life threatening medical state complicating the use of antipsychotic medications and other drugs that affect the dopaminergic system on administration or withdrawal. …”
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The role of peroxisome proliferator-activated receptor in the treatment of non-alcoholic fatty liver disease by Sun Xin, Zhang Yan, Xie Meilin

“…Peroxisome proliferator-activated receptors (PPARs) are among the potential targets and have been demonstrated to exert a pivotal role in modulation of NAFLD. Many drugs developed so far are targeted at PPARs. Thus, the aim of this paper is to summarize the roles of PPARs in the treatment of NAFLD.…”
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SYNTHESIS AND CHARACTERIZATION OF NEW POLYMERIC COATINGS FROM ANTHOCYANIN DYE AND STUDY BIOLOGICAL ACTIVITY by Mayson Thafir Hadi, Zainab A. Jabarah, Sana H. Awad

“… This study was aimed to prepared new polymeric coverings reinforced by the naturally occurring pigment anthocyanins and investigate their biological efficacy when combined with certain drugs against specific kinds of microbe’s pathogens. …”
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Tailored Therapy in Lung Cancer by George Rakovich, Lise Tremblay

“…Advances in molecular biology have made possible the development of drugs against specific molecular targets on cancer cells, most notably the tyrosine kinase inhibitors. …”
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A Validated RP – HPLC Method for Simultaneous Estimation of Cefixime and Cloxacillin in Tablets by G. Rathinavel, P. B. Mukherjee, J. Valarmathy, L. Samueljoshua, M. Ganesh, T. Sivakumar, T. Saravanan

“…The developed method is rapid and sensitive and it can be used for estimation of combination of these drugs in tablets.…”
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