Omega-3 fatty acids: molecular weapons against chemoresistance in breast cancer by Vittoria Marchio, Giuseppina Augimeri, Catia Morelli, Adele Vivacqua, Cinzia Giordano, Stefania Catalano, Diego Sisci, Ines Barone, Daniela Bonofiglio

“…This review aims to provide an overview of the molecular mechanisms driving breast cancer chemoresistance, focusing on the role of ω-3 PUFAs in these recognized cellular paths and presenting current findings on the effects of ω-3 PUFAs combined with chemotherapeutic drugs in breast cancer management.…”
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Pyrogallol acts as a novel anticancer factor to enhance the sensitivity to cisplatin in ovarian cancer cells through inducing miR-15a upregulation by Azin Shirani, Razieh Mirabbasi, Leila Shabani, Somayeh Reiisi

“…Methods In the present study, ovarian carcinoma cell line A2780 was cultivated, and the anticancer properties of pyrogallol and cisplatin determined by cell treatment of the two drugs separately and combination. Cell viability and apoptosis rate was investigated by MTT assay and flow cytometry. …”
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DETECTION, IDENTIFICATION, AND ANTIBIOTIC RESISTANCE PATTERNS OF FOODBORNE BACTERIAL AND FUNGAL PATHOGENS by Shakir Ullah, Hayat Khan, Usman Saeed, Ismail Shahid, Yasir Zubair, Maryam Bibi, Umair Islam, Basit Ali, Usman Shah, Muhammad Iqbal Khan Rahman

“…Mucor spp. proved relatively more susceptible to all anti-fungal drugs. The only Fusarium spp. isolate was highly resistant to all anti-fungal in this research. …”
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Pretreatment with serine protease inhibitors impairs Leishmania amazonensis survival on macrophages by Patrícia de Almeida Machado, Pollyanna Stephanie Gomes, Elaine Soares Coimbra, Herbert Leonel de Matos Guedes

“…The discovery of new therapeutic alternatives is extremely essential, and the discovery of cellular targets is a tool that helps in the development of new drugs. Serine proteases emerge as important virulence factors in the Leishmania genus, as they participate in important processes involved in their infectivity, virulence, and survival. …”
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The potential of Curcuma longa L. bioactive compounds as RSK inhibitors for the treatment of prostate cancer: in silico study by Olusola Olalekan Elekofehinti, Foluso Adeola Taiwo, Moses Orimoloye Akinjiyan, Ifeoluwa Rachael Adetoyi, Folasade Oluwatobiloba Ayodeji, Adedotun Olayemi Oluwatuyi, Oluwapelumi Nifesimi Akintoye, Idayat Oyinkansola Kehinde, Bolanle Esther Adedapo, Opeyemi Iwaloye

“…Results Five bioactive compounds may be possible lead drugs for the treatment of prostate cancer because they have the lowest binding energies, ranging from − 9.0 kcal/mol to − 11.00 kcal/mol, and have better pharmacokinetic qualities than the standard drugs docetaxel, enzalutamide, and abiraterone. …”
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Clinical and Epidemiological Characterization of Patients with Rheumatoid Arthritis by Zoe Alina González Otero, Jorge Luis Egüez Mesa, Celestino Fusté Jiménez, Eugenio Alejandro Reyes Medina, José Alberto Borges López, Lázaro Hermes González Otero

“…The most common treatment was the combination of non-steroidal anti-inflammatory drugs and steroids.…”
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Psychobiotics, Novel Therapeutic Agents for the Psychiatric Disorders by Praveen Reddy P., K. Sandhya, Aparna Srikantam

“…Some of the researchers are employing psychobiotics in combination with traditional drugs for treatment of the psychiatric disorders. …”
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Transfusion and Risk of Infection in Canada: Update 2005

“…This is in contrast to drugs that can be manufactured de novo under sterile conditions in a laboratory. …”
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Pharmacokinetic Interactions between Cardiovascular Medicines and Plant Products by Irina-Iuliana Costache, Anca Miron, Monica Hăncianu, Viviana Aursulesei, Alexandru Dan Costache, Ana Clara Aprotosoaie

“…Plant products can influence pharmacokinetics or/and pharmacological activity of coadministered drugs and some of these interactions may lead to unexpected clinical outcomes. …”
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From the Cytoplasm into the Nucleus—Hepatitis B Virus Travel and Genome Repair by Johan Ringlander, Gustaf E. Rydell, Michael Kann

“…Understanding the intracellular transport and genome repair mechanisms of HBV is crucial for developing new drugs, which—in combination with immune modulators—may contribute to potential cures. …”
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Synthesis and Antifungal Activities of 5-(o-Hydroxy phenyl)-2-[4'aryl-3'chloro-2'azetidinon-1-yl]-1,3,4-thiadiazole by Shiv K. Gupta, P. K. Sharma, M. Bansal, B. Kumar

“…In vitro antifungal activity (MIC activity) was evaluated and compared with standard drugs of ketoconazole. Compounds 3c in the series has shown interesting antifungal activity against both C. albicans and A. niger fungus. …”
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Is It Safe to Restart Antivascular Endothelial Growth Factor Therapy in Patients with Renal Cell Carcinoma after Cardiac Ischemia? by Bo Zhao, Laura S. Wood, Karen James, Brian I. Rini

“…Agents targeting vascular endothelial growth factor (VEGF) represent active drugs in treating patients with advanced renal cell carcinoma (RCC). …”
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European Society for Neurogastroenterology and Motility Consensus on Gastroparesis: What Issues Remain Unresolved? by A. A. Sheptulin, A. S. Trukhmanov, O. A. Storonova, D. E. Rumyantseva

“…At the same time, there is a divergence of views regarding the role of individual pathogenetic factors of gastroparesis and their relationship with clinical symptoms, as well as the effectiveness of drugs of various groups and other treatment methods.Conclusion. …”
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Developments in Platinum-Group Metals as Dual Antibacterial and Anticancer Agents by Ayodele T. Odularu, Peter A. Ajibade, Johannes Z. Mbese, Opeoluwa O. Oyedeji

“…Sandwich and half-sandwich PGM coordination compounds and their metal nanoparticles give improved results for biological activities by enhancing efficient delivery of both antibacterial and anticancer drugs, as well as luminescent bioimaging (biomarkers) for biological identifications.…”
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Conjugation of Daunorubicin to Monoclonal Antihuman Sarcoma Antibody by a Novel Method by Michel Pagé, Denis Thibeault, Hélène Tremblay, Christiane Noël, Marie-Josée Perron

“…Most of the reported methods for coupling anthracycline drugs to antibody result in either a loss of pharmacological activity or yield antibodies which have lost much of their immunological specificity. …”
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Simultaneous Bilateral Quadriceps Tendon Rupture following Long-Term Low-Dose Nasal Corticosteroid Application by Mohamed Omar, Philipp Haas, Max Ettinger, Christian Krettek, Maximilian Petri

“…Occurrence after minor trauma is predominantly associated with certain medical conditions including chronic diseases and long-term use of certain drugs. We report the case of a 61-year-old healthy patient who sustained a simultaneous bilateral quadriceps tendon rupture following minor trauma. …”
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Anesthetic Management of Total Aortic Arch Replacement in a Myasthenia Gravis Patient under Deep Hypothermic Circulatory Arrest by Mamiko Kondo, Yusuke Yoshikawa, Hirofumi Terada, Michiaki Yamakage

“…We describe a case of successful anesthetic management of a myasthenia gravis patient undergoing total arch replacement with deep hypothermic circulatory arrest under neuromuscular monitoring and complete reversal of the action of neuromuscular blocking drugs by sugammadex. The present case suggests that patients with well-controlled myasthenia gravis might be safely managed in cardiac or aortic surgery under cardiopulmonary bypass with deep hypothermic circulatory arrest.…”
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Ovulation Induction Techniques in Polycystic Ovary Syndrome - Systematic Review by Daria Michałka, Natalie Papachristoforou, Natalia Tekiela, Zuzanna Gałuszka, Monika Makar, Tomasz Bartuś, Emilia Bąk, Justyna Głowacka, Aleksandra Kocjan, Radosław Chmiel

“…To address this issue comprehensively, we specifically selected six main treatment methods: lifestyle changes, clomiphene citrate, antidiabetic drugs, gonadotropin analogues, aromatase inhibitors, and surgical approaches. …”
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Analysis of Size Correlations for Microdroplets Produced by Ultrasonic Atomization by Annalisa Dalmoro, Anna Angela Barba, Matteo d’Amore

“…Microencapsulation techniques are widely applied in the field of pharmaceutical production to control drugs release in time and in physiological environments. …”
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Advances in Pathogenesis of Sjögren’s Syndrome by Yao Tian, Hongyi Yang, Na Liu, Yan Li, Jie Chen

“…A systematic review of the literature may clarify the etiology and pathogenesis of SS, as well as provide a theoretical basis for the development of new drugs for the treatment of SS.…”
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