Dynamic changes of peptidome and release of polysaccharide in sea cucumber (Apostichopus japonicus) hydrolysates depending on enzymatic hydrolysis approaches by Yanchao Wang, Yan Song, Yaoguang Chang, Yanyan Liu, Guangning Chen, Changhu Xue

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Human drone interaction in delivery of medical supplies: A scoping review of experimental studies. by Franziska Stephan, Nicole Reinsperger, Martin Grünthal, Denny Paulicke, Patrick Jahn

“…These studies investigated the user experience of drone delivered defibrillators, but no study was identified that investigated the human drone interaction in the delivery of drugs. Three categories of human drone interaction were identified: landing, handover, and communications. …”
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Resistant stomach ulcer at Cushing disease: clinical case by N. V. Novozhilov, Yu. O. Shulpekoa, S. V. Mironov, Ye. K. Baranskaya, A. A. Sheptulin, V. T. Ivashkin

“…Initially these symptoms were inaccurately attributed to osteoarthrosis, thus patient received nonsteroid anti-inflammatory drugs (NSAID) and high doses of Kenalog. Later classical symptoms of hypercorticoidism - characteristic changes of the face, visceral obesity, striae, systemic hypertension and diabetes mellitus became obvious. …”
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Study of Component Composition and Antimicrobial Activity of the Ophthalmic Emulsion Based on the Safflower Flowers (Carthamus tinctorius L.) by Zhanar Abuova, Aknur Turgumbayeva, Ardak Jumagaziyeva, Kairolla Rakhimov, Aigul Jussupkaliyeva

“…Many antibacterial and anti-inflammatory synthetic drugs are available in medical practice. However, recent tendency of increasing capability of resistance of bacteria to usage of antibacterial drugs of different groups is taking place. …”
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COLORATION AND DISCOLORATION OF OLVEOLAR BONE AND TOOTH ENAMEL CAUSED BY MEDICATION by Giurgiu Cristian Levente, George Morarasu, Nicolae Baranov, Pogăcian-Maier Alexandra-Camelia, Radu-Mircea Sireteanu-Cucui, Cristina Pipa, Alina Monica Miftode, Alina Stefanache

“…Conclusion: Medication-induced tooth discoloration presents significant clinical challenges due to its varied mechanisms, including intrinsic staining from systemic incorporation of drugs and extrinsic staining from surface agents. …”
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Nootkatone inhibits the progression of glioblastoma by activating the ATF4-CHOP-CHAC1 pathway by Qian Wang, Xiumin Xue, Zhichao Chen, Wei Zhang, Yiming Qian, Danni Chen, Lin Lin, Yinfeng Yuan, Weiqiao Zhao, Zhihui Huang, Yongjie Wang

“…Abstract Glioblastoma multiforme (GBM) represents a primary brain tumor that is widely prevalent, and clinical drugs available for its treatment exhibit varying degrees of resistance. …”
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SGLT2i and GLP-1RA in Cardiometabolic and Renal Diseases: From Glycemic Control to Adipose Tissue Inflammation and Senescence by Luis D'Marco, Valery Morillo, José Luis Gorriz, María K. Suarez, Manuel Nava, Ángel Ortega, Heliana Parra, Nelson Villasmil, Joselyn Rojas-Quintero, Valmore Bermúdez

“…In this sense, and in addition to being used for glycemic control in diabetic patients, these drugs also have other favorable effects such as weight loss and lowering blood pressure, and more recently, they have been shown to have cardio and renoprotective effects with anti-inflammatory properties. …”
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Choroidal Detachment after XEN Gel Stent Implantation by Carlo Alberto Cutolo, Letizia Negri, Sara Olivari, Francesca Cappelli, Carlo Enrico Traverso, Michele Iester

“…Older age, lower postoperative IOP, and higher number of preoperative IOP-lowering drugs were significantly associated with the development of CD.…”
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Determination of Mycotoxins and Veterinary Medicines in Duck Flesh and Viscera and Assessment of Their Exposure by Yi Zheng, Yuxin Wu, Huanxin Zhang, Xiaolan Chen, Zaixiang Lou, Huijuan Jing, Chunpeng (Craig) Wan

“…Co-occurrence of veterinary drugs was verified in several samples.…”
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Meta-analysis of the clinical efficacy of liraglutide in treating type 2 diabetes mellitus complicated with non-alcoholic fatty liver disease by Yuan-Yuan Xu, Xu Wang, Yu-Qing She, Jie Liu, Qing Zhang

“…This study aimed to systematically evaluate the efficacy of liraglutide in treating type 2 diabetes mellitus (T2DM) complicated with non-alcoholic fatty liver disease (NAFLD) by comparing liraglutide with placebo or other drugs (mainly insulin). The PubMed, Web of Science, and National Library of Medicine databases were systematically searched from their inception until December 1, 2023. …”
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Mechanism of Cordyceps Cicadae in Treating Diabetic Nephropathy Based on Network Pharmacology and Molecular Docking Analysis by Yi Qian, Xin Sun, Xin Wang, Xin Yang, Mengyao Fan, Jiao Zhong, Zejun Pei, Junping Guo

“…Active ingredients of cordyceps cicadae such as myriocin may act on DN through different targets such as AKT1, MAPK8, and TP53 and other targets, which can help to develop innovative drugs for effective treatment of DN.…”
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The impact of sodium-glucose cotransporter-2 inhibitors on the incidence, therapy, and outcomes of fournier gangrene: insights from a systematic review of case reports by Yufi Aulia Azmi, Firas F. Alkaff, Kevin Muliawan Soetanto, Soetojo Wirjopranoto, Maarten J. Postma, Abdul Khairul Rizki Purba

“…Therapy was performed by replacing SGLT2i with other anti-diabetic drugs. The patient's outcome improved after treatment.…”
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Effectiveness of positive allosteric modulators of metabotropic glutamate receptor 2/3 (mGluR2/3) in animal models of schizophrenia by David Olivares-Berjaga, Albert Martínez-Pinteño, Natalia Rodríguez, Sergi Mas, Constanza Morén, Eduard Parellada, Patricia Gassó

“…Current antipsychotic drugs ameliorate the positive symptomatology, but are inefficient in treating the negative symptomatology and cognitive deficits. …”
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Metformin for Treating Gestational Diabetes: What Have We Learned During the Last Two Decades? A Systematic Review by Angeliki Gerede, Ekaterini Domali, Christos Chatzakis, Chrysoula Margioula-Siarkou, Stamatios Petousis, Sofoklis Stavros, Konstantinos Nikolettos, Evanthia Gouveri, Sotirios Sotiriou, Panagiotis Tsikouras, Konstantinos Dinas, Nikolaos Nikolettos, Nikolaos Papanas, Dimitrios G. Goulis, Alexandros Sotiriadis

“…The objective of this review was to comprehensively analyze all studies investigating the effectiveness of metformin compared to insulin and other drugs utilized for the treatment of GDM. After a comprehensive literature review based on PRISMA 2020, 35 studies were included after a selection process utilizing predetermined inclusion and exclusion criteria. …”
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Early Treatment with Intranasal Neostigmine Reduces Mortality in a Mouse Model of Naja naja (Indian Cobra) Envenomation by Matthew R. Lewin, Stephen P. Samuel, David S. Wexler, Philip Bickler, Sakthivel Vaiyapuri, Brett D. Mensh

“…Acetylcholinesterase inhibitors can be therapeutic in neurotoxic envenomations when administered intravenously, but nasally delivered drugs could facilitate prehospital therapy for these patients. …”
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Comparison the Efficacy of Fluconazole and Terbinafine in Patients with Moderate to Severe Seborrheic Dermatitis by Narges Alizadeh, Hamed Monadi Nori, Javad Golchi, Shahriar S. Eshkevari, Ehsan Kazemnejad, Abbas Darjani

“…The itching rate significantly diminished (P<0.001); however, there was no difference between these two drugs statistically. Conclusions. Both systemic antifungal therapies may reduce the severity index of SD. …”
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In Vivo Antimalarial Activity of 80% Methanol and Aqueous Bark Extracts of Terminalia brownii Fresen. (Combretaceae) against Plasmodium berghei in Mice by Hana Biruk, Biruk Sentayehu, Yonatan Alebachew, Wondmagegn Tamiru, Abebe Ejigu, Solomon Assefa

“…Evergrowing resistance towards the currently available antimalarial drugs is a challenge to combat malaria. Medicinal plants are a promising source of new drugs to tackle this problem. …”
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Evaluation of the Antimicrobial Properties of the Essential Oil of Myrtus communis L. against Clinical Strains of Mycobacterium spp. by Stefania Zanetti, Sara Cannas, Paola Molicotti, Alessandra Bua, Marina Cubeddu, Silvia Porcedda, Bruno Marongiu, Leonardo Antonio Sechi

“…The World Health Organization has estimated that 8 million of people develop active TB every year and the situation is complicated by an increase of Mycobacterium tuberculosis strains resistant to drugs used in antitubercular therapy: MDR and XDR-TB. …”
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Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus by Abdallah Rahbani, Grace Adwane, Najo Jomaa

“…He was given 4 mg of Perampanel orally via nasogastric tube and the dose was rapidly increased to 8 mg after 12 hours with cessation of clinical and electrical seizures. Other antiepileptic drugs were tapered progressively with an excellent clinical outcome.…”
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Cytokines as cellular communicators by R. Debets, H. F. J. Savelkoul

“…Translation of this diverse regulation in strategies aimed at the control of cytokine activity will result in the development of more specific and selective drugs to treat diseases.…”
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