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7881
Loading and Skeletal Development and Maintenance
Published 2011-01-01“…There are few data on a possible additive effect of exercise and drugs in osteoporosis treatment, but disuse could decrease drugs action. …”
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7882
Lyophilised protein formulations as a patient-centric dosage form: A contribution toward sustainability paradigm
Published 2024-06-01“…At present, society has embraced the fact apropos population aging and climate changes, that demand, amongst others, innovative pharmaceutical technologies, emphasising the development of patient-specific delivery systems and thus the provision of efficient and sustainable drugs. Protein drugs for subcutaneous administration, by allowing less frequent application, represent one of the most important parts of the pharmaceutical field, but their development is inevitably faced with obstacles in providing protein stability and suitable formulation viscosity. …”
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7883
NMR, Novel Pharmacological and In Silico Docking Studies of Oxyacanthine and Tetrandrine: Bisbenzylisoquinoline Alkaloids Isolated from Berberis glaucocarpa Roots
Published 2018-01-01“…So, there is a strong need to develop new and safe antiurease drugs, particularly from natural sources. In search for new and effective drugs from natural sources bioassay-guided fractionation and isolation of Berberis glaucocarpa Stapf roots bark resulted in the isolation and characterization, on the basis of 1D and 2D NMR data, of two bisbenzylisoquinoline alkaloids, oxyacanthine (1) and tetrandrine (2), followed by urease inhibition studies. …”
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7884
Novel Pt (II) Complexes With Anticancer Activity Against Pancreatic Ductal Adenocarcinoma Cells
Published 2024-01-01“…However, the development of resistance to chemotherapy drugs has created a need for the synthesis of new anticancer agents. …”
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7885
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7886
Design and Synthesis of Small Molecules Based on a Substructural Analysis of the Histone Deacetylase Inhibitors TSA and SAHA
Published 2011-01-01“…Inhibitors of histone deacetylases (HDACs) are patent inducers of differentiation and bear considerable potential as drugs for chemoprevention and treatment of cancer. …”
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7887
MUC5AC mucin release from human airways in vitro: Effects of indomethacin and Bay X1005
Published 2001-01-01“…While the current pharmacological approach to reducing mucus and sputum production in patients is limited, clinical studies have suggested that drugs which inhibit the cyclooxygenase and/or 5-lipoxygenase enzymatic pathways may reduce secretory activity in patients with airway disease.…”
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7888
Association of Inflammation with Metabolic Syndrome among Low-Income Rural Kazakh and Uyghur Adults in Far Western China
Published 2015-01-01“…And it found that improving behavioral lifestyle by education or using drugs to control inflammation may prevent MS. These observations may benefit low-income populations.…”
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7889
Esophageal pH Testing in Patients Refractory to Proton Pump Inhibitor Therapy
Published 2008-01-01“…BACKGROUND: Proton pump inhibitors (PPIs) are the most potent drugs available for the management of gastroesophageal reflux disease (GERD). …”
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7890
Uveitis associated with elevation of intraocular pressure – what is the optimal therapy?
Published 2023-12-01“…If SIG is diagnosed, it is necessary to modify the glucocorticosteroid treatment to maintain a balance between controlling inflammation and normalizing the IOP. β-blockers and carbonic anhydrase inhibitors are the first-line anti-glaucoma drugs in the treatment of SIG in patients with uveitis. α-2 agonists are classified as second-line drugs. …”
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7891
ESTIMATION OF USING MEDICATIONS OF DIFFERENT GROUPS FOR COMMUNITY-ACQUIRED PNEUMONIA TREATMENT OF PATIENTS WITH COMORBIDITIES
Published 2017-03-01“…Complicated chronic diseases in patients with CAP caused prescription of 13,7 ± 5,0 drugs. CAP in-patients with uncontrolled chronic diseases received 11,0 ± 2,9 medicines. …”
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7892
Current Molecular Targeted Therapy in Advanced Gastric Cancer: A Comprehensive Review of Therapeutic Mechanism, Clinical Trials, and Practical Application
Published 2016-01-01“…Due to the molecular study of gastric cancer, new molecular targeted drugs have entered the clinical use. Trastuzumab, an antibody targeting human epidermal growth factor receptor 2 (HER2), can significantly improve survival in advanced gastric cancer patients with HER2 overexpression. …”
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7893
Memory-Enhancing Activity of Palmatine in Mice Using Elevated Plus Maze and Morris Water Maze
Published 2012-01-01“…Palmatine (0.1, 0.5, 1 mg/kg, i.p.) and physostigmine (0.1 mg/kg, i.p.) per se were administered for 10 successive days to separate groups of mice. Effect of drugs on learning and memory of mice was evaluated using elevated plus maze and Morris water maze. …”
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7894
Tissue Factor Expression in Obese Type 2 Diabetic Subjects and Its Regulation by Antidiabetic Agents
Published 2015-01-01“…Regulation of TF activity by different classes of antidiabetic drugs may relate to protective or adverse cardiovascular outcomes.…”
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7895
Endodontists’ Self-Assessment about Pharmacological Strategies for Management of Endodontic Pain
Published 2025-01-01“…Dipyrone (72.6%) and ibuprofen (56.8%) were the most prescribed systemic drugs. The most used local anesthetics were mepivacaine (58.2%) and articaine (57.5%). …”
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7896
Quality assessment of furosemide tablet generics used in a teaching hospital in Nigeria
Published 2025-02-01“… The use of ineffective and poor-quality drugs endangers treatment leading to treatment failure. …”
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7897
Anti-Hyperlipidemic Effect of Zinc complex of Betulinic acid in High Fat Diet- Induced Hyperlipidemia
Published 2023-04-01“…To tackle the shortcomings of standard drugs, there is dire demand to make an agent which equates to a better response. …”
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7898
BARRIER OF REFERRAL–BACK IN SECONDARY HEALTH FACILITIES: PROVIDER AND PATIENT PERSPECTIVES
Published 2024-12-01“…Results: From the provider's perspective, issues included low commitment of medical staff, lack of coordination between the hospital and PHC, limited supply of RBP drugs at the PHC, absence of Standard Operating Procedures (SOPs), and ignorance of notifications regarding potential RBP patients. …”
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7899
Diet at intestinal diseases: traditional bases and new discoverings
Published 2011-06-01“…Development of alimentary additives and drugs on their basis is going on. Application of pre- and probiotics for stimulation of regeneration and development of functional nutrition products on their basis invokes major interest.Conclusion. …”
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7900
Deteksi Bakteri Patogen Pada Daging Ayam Broiler Sebagai Skrining Foodborne Diseases Di Kabupaten Jember
Published 2024-12-01“…However, as production increases, certain drugs and feed additives become essential for disease prevention, treatment, and growth promotion. …”
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