Pharmacological Treatment of Obesity in Children and Adolescents: Present and Future by Lorenzo Iughetti, Mariachiara China, Rossella Berri, Barbara Predieri

“…Considering that our knowledge on the physiological systems regulating food intake and body weight is considerably increased, many studies have underlined the scientific and clinical relevance of potential treatments based on management of peripheral or central neuropeptides signals by drugs. In this paper, we analyze the data on the currently approved obesity pharmacological treatment suggesting the new potential drugs.…”
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Bullous pemphigoid as a diagnostic and therapeutic challenge with a wide spectrum of dermatological symptoms by Przemysław Borowy, Olga Wcisłek, Julia Płonczyńska, Mateusz Heba, Bogdan Batko

“…The case presents diagnostic challenges and various forms of topical therapy in a patient with multiple diseases responsible for limited access to recommended drugs.…”
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Colorectal Cancer Chemoprevention: Is This the Future of Colorectal Cancer Prevention? by A. Manzano, P. Pérez-Segura

“…Chemoprevention seems to be an attractive option in this setting and several drugs have been studied in this field. This review is focused on salicylates, nonsteroidal anti-inflammatory drugs (NSAIDs) and cycloxygenase-2 inhibitors (COXIBs), whose mechanism of action could be directly related to colon cancer chemoprevention.…”
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Effect of ranolazine on the course of ischemic heart disease after percutaneous coronary intervention by О.А. Yepanchintseva, O.J. Zharinov, І.V. Shklianka

“…Potential advantages of ranolazine compared with other second-line antianginal drugs are the absence of significant changes in hemodynamic parameters, good tolerability and proven antiarrhythmic effects.…”
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A Narrative Review of Existing Options for COVID-19-Specific Treatments by Wasey Ali Yadullahi Mir, Abdul Hasan Siddiqui, Gautam Valecha, Shawn Patel, Fatima Ayub, Riddhi Upadhyay, Sana Ahmed Alhajri, Suman Gaire, Dhan Bahadur Shrestha

“…Therefore, drugs targeting various pathologic aspects of the disease are being explored. …”
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Optimal Control of Multiple Transmission of Water-Borne Diseases by G. Devipriya, K. Kalaivani

“…The controls represent an immune boosting and pathogen suppressing drugs. The objective function is based on a combination of minimizing the number of infected individuals and the cost of the drugs dose. …”
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Antibacterial and Oxacillin Resistance Reversing Effect of Harmaline in Different Strains of Staphylococcus Aureus by Zaid Ibraheem

“…Eventually, the interaction between the two drugs for the bactericidal effect was screened using the well-known isobologram technique.Results: The results showed that harmaline got a mild to moderate bactericidal effect against MRSA and produced a moderate synergistic effect when both drugs were combined at a ratio of 3:7 and 5:5 (harmaline/oxacillin). …”
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Role of microglia in the pathogenesis of multiple sclerosis and links to immunomodulatory therapy by P. Valiukevičius, R. Liutkevičienė, R. Balnytė

“…Many of the disease-modifying drugs used to treat multiple sclerosis also affect microglial cells and inhibit their inflammatory response. …”
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Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism by Sander Kersten

“…An important group of transcription factors that mediates the effect of dietary fatty acids and certain drugs on plasma lipoproteins are the peroxisome proliferator activated receptors (PPARs). …”
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Evaluation of Current Households Management Practices of Solid Wastes from Pharmaceuticals in Soc Trang city, Vietnam by T. T. Tien, N. T. Giao

“…The results showed that more than 300 different pharmaceutical brand names belonging to 14 groups of pharmaceutical drugs have been used in which digestive, pain relievers, antipyretics, steroid anti-inflammatory drugs, gout, bone and joint diseases, cardiovascular, parasitic, anti-inflammatory, antiviral, and antifungal drugs were the commons. …”
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The effect of anesthesia on postoperative cognitive dysfunction in adults undergoing cataract surgery: a systematic review by Elaheh Foroughi, Etrusca Brogi, Francesco Forfori, Seyyed Taghi Hashemi

“…Abstract Background We systematically reviewed the evidence on the effect of anesthetic methods and drugs on the incidence of postoperative cognitive dysfunction (POCD) after cataract surgery. …”
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Bleomycin pollution and lung health: The therapeutic potential of peimine in bleomycin-induced pulmonary fibrosis by inhibiting glycolysis by Kangchen Li, Xuefang Liu, Ruilong Lu, Peng Zhao, Yange Tian, Jiansheng Li

“…The increasing use of anticancer drugs has led to the emergence of environmental contaminants such as bleomycin (BLM), which poses significant threats to both aquatic ecosystems and human health. …”
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Analysis of Misdiagnosis of 4 Cases of Tuberculosis of Thyroid and Literature Review by De-Tao Yin, Wenxun Wu, Shengli Cao, Hongqiang Li

“…The first choice was treatment with anti-tuberculosis drugs.…”
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Considerations for the use of anesthesia in patients undergoing tricyclic antidepressant treatment by Iván Hamyd Salazar Carrera

“…Patients undergoing tricyclic antidepressant treatment given anesthesia have experienced the hypotensive effects of both drugs. Traditionally it was recommended to suspend these drugs until two weeks before surgery; however, it is currently proposed that they should not be discontinued, since despite the side effects and possible interactions with anesthetic agents, cases of suicide have been described after its suspension. …”
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Modulation of Immunity by Antiangiogenic Molecules in Cancer by Magali Terme, Orianne Colussi, Elie Marcheteau, Corinne Tanchot, Eric Tartour, Julien Taieb

“…In the last decades a new class of therapeutic drugs have been developed that block tumor angiogenesis. …”
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A year in review: new treatments and expanded indications in dermatology in 2024 by Lauren N. McGrath, Lila G. McGrath, John R. Edminister

“…Innovations in new medications transform clinical practice and provide dermatologists new opportunities to enhance patient care.Methods A literature search was conducted on Drugs@FDA: FDA-Approved Drugs for the year 2024 to identify new dermatologic treatments.Results In 2024, the FDA approved seven new dermatologic therapies and expanded the indications for seven current therapies. …”
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Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids by Arun Sridhar, Ingunn Bakke, Shreya Gopalakrishnan, Nimo Mukhtar Mohamud Osoble, Emilie Prytz Hammarqvist, Henrik P. Sahlin Pettersen, Arne Kristian Sandvik, Ann Elisabet Østvik, Marianne Doré Hansen, Torunn Bruland

“…However, the impact of immune cell-modulating IBD drugs on epithelial homeostasis and repair is poorly understood. …”
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The Epidemiology of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in China by Shang-Chen Yang, Sindy Hu, Sheng-Zheng Zhang, Jin-wen Huang, Jing Zhang, Chao Ji, Bo Cheng

“…The most common offending drugs were antibiotics (29.5%) and anticonvulsants (24.1%). …”
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Practical Recommendations of Scientific Society for the Study of Human Microbiome and Russian Gastroenterological Association (RGA) for Probiotics in Treatment and Prevention of Ga... by V. T. Ivashkin, I. V. Mayev, D. I. Abdulganieva, S. A. Alekseenko, N. Yu. Ivashkina, N. V. Korochanskaya, S. N. Mammaev, E. A. Poluektova, A. S. Trukhmanov, Yu. P. Uspensky, V. V. Tsukanov, O. S. Shifrin, O. Yu. Zolnikova, K. V. Ivashkin, T. L. Lapina, R. V. Maslennikov, A. I. Ulyanin

“…Not all probiotics registered in the Russian Federation as BAFA or drugs contain bacterial or fungal strains; as a result, the expected clinical effect may not be achieved.…”
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Practical Recommendations of Scientific Society for the Study of Human Microbiome and the Russian Gastroenterological Association on Use of Probiotics, Prebiotics, Synbiotics and F... by V. T. Ivashkin, I. V. Maev, D. I. Abdulganieva, S. A. Alekseenko, A. V. Gorelov, I. N. Zakharova, O. Yu. Zolnikova, N. Yu. Ivashkina, N. V. Korochanskaya, S. N. Mammayev, E. A. Poluektova, A. S. Trukhmanov, D. V. Usenko, Yu. P. Uspensky, V. V. Tsukanov, O. S. Shifrin, I. V. Berezhnaya, K. V. Ivashkin, T. L. Lapina, R. V. Maslennikov, S. V. Nikolaeva, N. G. Sugyan, A. I. Ulyanin

“…Not all probiotics registered in Russia as BAFAs, drugs and FFPs have a strain identity, which provides no warranty of the clinical effect expected. …”
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