Regional environmental impacts on growth traits and phytochemical profiles of Glycyrrhiza glabra L. for enhanced medicinal and industrial use by Ghasem Eghlima, Yasaman Mashhadi Tafreshi, Fateme Aghamir, Hamid Ahadi, Mehrnaz Hatami

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Advances in preclinical and clinical studies of oncolytic virus combination therapy by Wenlong Du, Jintong Na, Liping Zhong, Liping Zhong, Pumin Zhang

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Asymmetric synthesis of stereogenic-at-iridium(III) complexes through Pd-catalyzed kinetic resolution by Yun-Peng Chu, Xue-Lin Yue, De-Hai Liu, Chuanyong Wang, Jiajia Ma

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Therapeutic alternatives for sporotrichosis induced by wild-type and non-wild-type Sporothrix schenckii through in vitro and in vivo assessment of enilconazole, isavuconazole, posa... by Vasurom Aroonvuthiphong, Norasuthi Bangphoomi

“…Abstract This study explores the effectiveness of various antifungal drugs in treating sporotrichosis caused by Sporothrix schenckii, especially in non-wild-type (non-WT) strains. …”
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New treatment options for generalized myasthenia gravis by Antanas Vaitkus, J. Čiauškaitė, M. Malakauskaitė, M. Baublytė

“…We focus more on already approved biological drugs. …”
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A European Approach to Irritable Bowel Syndrome Management by Michel Delvaux, Jacques Frexinos

“…In contrast, psychotropic drugs are less popular among European gastroenterologists than among American gastroenterologists. …”
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Subcutaneous Dorsal Penile Vein Thrombosis or Penile Mondor’s Disease: A Case Report and Literature Review by Adama Ouattara, Abdoul Karim Paré, Aristide F. Kaboré, Clotaire Yaméogo, Gnimdou Botcho, Désiré Ky, Abdoul Aziz Ouédraogo, Amidou Bako, Rigobert Kiba, Zakari Nikiéma, Timothée Kambou

“…The patient receives nonsteroidal anti-inflammatory drugs and coagulation and platelet aggregation inhibitors drugs. …”
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Circadian Rhythms Fluctuate the Treatment Effects of Intravesical Treatments on Rat Urinary Frequency Models by Tomofumi Watanabe, Takuya Sadahira, Yusuke Tominaga, Yuki Maruyama, Naoya Nagasaki, Takanori Sekito, Kohei Edamura, Toyohiko Watanabe, Motoo Araki, Masami Watanabe

“…Thirty minutes later, these drugs were voided, and rats were moved to a continuous urination monitoring system, UM-100. …”
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The role of luteinizing hormone activity in spermatogenesis: from physiology to clinical practice by Sandro C. Esteves, Peter Humaidan

“…We also examine the evidence regarding the effectiveness of LH-containing drugs in treating specific male infertility conditions and identify the main areas for future research. …”
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Quinoline and Quinazoline Alkaloids against COVID-19: An In Silico Multitarget Approach by Esraa M. O. A. Ismail, Shaza W. Shantier, Mona S. Mohammed, Hassan H. Musa, Wadah Osman, Ramzi A. Mothana

“…These alkaloids therefore have promise for being further investigated as possible multitarget drugs against COVID-19.…”
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Mesalazine in Inflammatory Bowel Disease: A Trendy Topic Once Again? by Marietta Iacucci, Shanika de Silva, Subrata Ghosh

“…Although most gastroenterologists are very familiar with these drugs, the interest in these drugs has undergone a resurgence, with new preparations offering convenience and high dosage, while preserving their customary safety. …”
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The Mechanism of Metabolic Influences on the Endogenous GLP-1 by Oral Antidiabetic Medications in Type 2 Diabetes Mellitus by Thiquynhnga Nguyen, Min Gong, Song Wen, Xinlu Yuan, Chaoxun Wang, Jianlan Jin, Ligang Zhou

“…However, recent studies indicate that oral antidiabetic medications interact with endogenous or exogenous GLP-1. Since these drugs are transported to distal intestine portions, there are concerns whether these oral drugs directly stimulate intestinal L cells which release GLP-1, or whether they do so via indirect inhibition of the activity of dipeptidyl peptidase-IV (DPP-IV). …”
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Peptide-Loaded Solid Lipid Nanoparticles Prepared through Coacervation Technique by Marina Gallarate, Luigi Battaglia, E. Peira, Michele Trotta

“…Insulin and leuprolide, chosen as model peptide drugs, were encapsulated within nanoparticles after hydrophobic ion pairing with anionic surfactants. …”
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Dynamic Modeling of the Angiogenic Switch and Its Inhibition by Bevacizumab by Dávid Csercsik, Levente Kovács

“…Furthermore, we show that a simple extension of the model is capable of considering cytotoxic and antiangiogenic drugs as inputs simultaneously in qualitatively different ways.…”
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Generation of Transplantable Beta Cells for Patient-Specific Cell Therapy by Xiaojie Wang, Daniel L. Metzger, Mark Meloche, Jianqiang Hao, Ziliang Ao, Garth L. Warnock

“…Islet cell transplantation offers a potential cure for type 1 diabetes, but it is challenged by insufficient donor tissue and side effects of current immunosuppressive drugs. Therefore, alternative sources of insulin-producing cells and isletfriendly immunosuppression are required to increase the efficiency and safety of this procedure. …”
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Artificial neural network systems to predict the response to sintilimab in squamous-cell non-small-cell lung cancer based on data of ORIENT-3 study by Tongji Xie, Guangyu Fan, Le Tang, Puyuan Xing, Yuankai Shi

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Immunosuppressive therapy of patients with pemphigus with ineffectiveness of systemic corticosteroids by Vadim V. Chikin, Arfenya E. Karamova

“…The drugs doses, the studies design, and criteria for evaluating the effectiveness of therapy in patients with pemphigus are considered. …”
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Promising New Treatments for Psoriasis by Sarah Dubois Declercq, Roxane Pouliot

“…Biological drugs are less toxic to the body and more effective than traditional therapies. …”
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Chemical Profiling Ethyl Acetate Extract of <i>Basilicum polystachyon</i> Leaves and Exploration of Anticancer SIRT1 Inhibitors Using <i>In Silico</i> Approach by Tukiran Tukiran, Muhammad Raihan

“…The development of new drugs is a major effort to solve the cancer problems. …”
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Pharmacotherapeutic Options for Managing Neuropathic Pain: A Systematic Review and Meta-Analysis by Giulia Di Stefano, Andrea Di Lionardo, Giuseppe Di Pietro, Giorgio Cruccu, Andrea Truini

“…Many drugs acting on new pain targets are currently under development. …”
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