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7121
A bibliometric analysis of hydrogel research in various fields: the trends and evolution of hydrogel application
Published 2025-01-01“…We encapsulated applications and the potential of hydrogel in wound healing, drug delivery, cell encapsulation, bioprinting, tissue engineering, electronic products, environment applications, and disease treatment. …”
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7122
Therapeutic target genes and regulatory networks of gallic acid in cervical cancer
Published 2025-01-01“…IntroductionThis study aims to identify the therapeutic targets and regulatory mechanisms of the antitumor drug gallic acid (GA) in cervical cancer (CC).MethodsHeLa cells were treated with GA and subjected to RNA-sequencing using the DNBSEQ platform. …”
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7123
Incorporating insulin into alginate-chitosan 3D-printed scaffolds: A comprehensive study on structure, mechanics, and biocompatibility for cartilage tissue engineering
Published 2025-03-01“…Histological analysis confirmed favorable biocompatibility and structural integrity of Insulin-loaded pure Alg and Alg-Cs scaffolds at drug loading levels of up to 20 and 10 μg, respectively. …”
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7124
Phα1β interaction with the Kv11.1 potassium channel in HEK293 cells transfected with the human ERG channel
Published 2025-01-01“…Over the past 15 years, our research has demonstrated the potential of Phα1β, in both its native and recombinant forms, as a promising analgesic drug through preclinical tests conducted on rodent pain models. …”
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7125
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7126
Genetic Diversity, Repeat Motifs, and Natural Selection at the C-Terminal Knob-Associated Histidine Rich Protein (KAHRP) of Plasmodium falciparum Clinical Samples from Saudi Arabia
Published 2022-01-01“…Since this is the first study to report on genetic diversity of C-terminal PfKAHRP interaction domain and the repeat motifs from clinical samples in Saudi Arabia, it will contribute towards the rational design of antiadhesion drug therapies for P. falciparum malaria.…”
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7127
Suitability of Measures of Pharmacy-Based Medication Adherence for Routine Clinical Use Among Patients with Chronic Diseases: A Systematic Review
Published 2025-01-01“…Wardatul Jannah,1,2 Qisty A Khoiry,1,2 Sofa D Alfian,1,2 Rizky Abdulah1,2 1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jatinangor, Indonesia; 2Drug Utilization and Pharmacoepidemiology Research Group, Center of Excellence for Pharmaceutical Care Innovation, Universitas Padjadjaran, Jatinangor, IndonesiaCorrespondence: Sofa D Alfian, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jl. …”
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7128
A global review of national guidelines of post‐exposure prophylaxis for the prevention of HIV
Published 2025-01-01“…Abstract Introduction The World Health Organization (WHO) recommends the use of antiretroviral drugs as post‐exposure prophylaxis (PEP) for preventing HIV acquisition for occupational and non‐occupational exposures. …”
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7129
TROPION-Breast04: a randomized phase III study of neoadjuvant datopotamab deruxtecan (Dato-DXd) plus durvalumab followed by adjuvant durvalumab versus standard of care in patients...
Published 2025-02-01“…Datopotamab deruxtecan (Dato-DXd), a TROP2-directed antibody-drug conjugate consisting of a humanized IgG1 monoclonal antibody attached via a plasma-stable cleavable linker to a topoisomerase-I inhibitor payload, has shown efficacy alone or in combination with durvalumab, a selective, high-affinity anti-programmed cell death ligand 1 antibody, in early-phase clinical studies. …”
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7130
Survey of the risk behaviors and mental health of adolescents in Gabon
Published 2024-11-01“…Six core modules (alcohol, tobacco, and drug use, sexual behaviors, mental health, and safety) were included. …”
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7131
FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques
Published 2024-12-01“…Because FcRn also regulates Ab half-life, Fc mutations like the M428L/N434S, commonly known as LS mutations, and others have been developed to enhance binding affinity to FcRn and improve drug pharmacokinetics. We hypothesized that these FcRn-enhancing mutations could similarly affect the delivery of therapeutic Abs to the fetus. …”
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7132
Melatonin Rescued Reactive Oxygen Species-Impaired Osteogenesis of Human Bone Marrow Mesenchymal Stem Cells in the Presence of Tumor Necrosis Factor-Alpha
Published 2019-01-01“…Accordingly, these findings provide more evidence that melatonin can be used as a candidate drug for the treatment of osteoporosis.…”
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7133
Correlation Between Inflammatory Markers and Pathogenic Bacteria in Children’s Winter Respiratory Infections in Xinjiang
Published 2025-01-01“…Lixia Wang,1,* Wei Wang,2,* Jian Wang,1 Ling Zhu,1 Jianjiang Luo1 1Department of Respiratory and Critical Care Medical Department Infectious Diseases Ward, The Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, Affiliated Traditional Chinese Medicine Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jianjiang Luo, Department of Respiratory and Critical Care Medical Department infectious diseases Ward, The Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, No. 116 Huanghe Road, Shayibake District, Urumqi, Xinjiang, People’s Republic of China, Tel +86013999946655, Email ljj.781201@163.comBackground: This study examines the distribution characteristics of pathogenic bacteria in respiratory infections and their relationship with inflammatory markers to guide clinical drug use.Methods: We selected 120 patients with lower respiratory tract infection in the electronic medical record system of Xinjiang Provincial People’s Hospital from March 2019 to March 2023 for a case-control study. …”
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7134
Socio-Demographic and Lifestyle Factors Influencing Adherence to AntiHypertensive Treatment in a Rural Area of Ludhiana, India
Published 2025-02-01“…Conclusions Hypertension is becoming a global health issue and is yet a preventable disease if timely and adequately treated. Non-adherence to drug therapy among anti-hypertensives is a matter worth concern. …”
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7135
Evaluation of the impact of acidic medications and fluoride-containing mouthwash on the enamel surface using quantitative light-induced fluorescence, microhardness, and scanning el...
Published 2025-01-01“…Therefore, this study aimed to assess the impact of acidic medications, specifically anti-asthmatic drugs and vitamin C tablets, on enamel surfaces and to investigate the effects of fluoride following drug exposure. …”
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7136
Mechanism of melanoma suppression by Prosopis juliflora derived alkaloids: Apoptosis induction and signaling pathway inhibition
Published 2025-02-01“…Additionally, PJLME-AF combined with dacarbazine, exhibited enhanced cytotoxicity on melanoma compared to the drug alone. Conclusion: PJLME-AF exhibit promising natural anti-cancer agents for metastatic melanoma treatment. …”
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7137
Evaluating the association between lipidome and female reproductive diseases through comprehensive Mendelian randomization analyses
Published 2025-01-01“…These lipid species may potentially serve as biomarkers and future drug targets for the treatment of FRDs.…”
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7138
Survival of Salmonella on Biodegradable Mulch, Landscape Fabric, and Plastic Mulch
Published 2025-02-01“…If counts dropped below the detection limit (<0.12 log CFU/cm2), enrichments were performed following the Food and Drug Administration’s Bacteriological Analytical Manual Salmonella protocol. …”
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7139
The protoplast two-way fusions and fusant characteristics of Antrodia cinnamomea and Cordyceps militaris
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7140
Study on the comparison between Bosentan and Macitentan in the treatment of persistent pulmonary hypertension of the newborns, simultaneously on sildenafil: A randomized double-bli...
Published 2025-01-01“…Background: Persistent Pulmonary Hypertension of the newborn (PPHN) is characterized by sustained elevated Pulmonary Artery Pressure (PAP). Drug resistance and the adverse effects of current therapeutic agents warrant investigation of other targeted therapies. …”
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