HIV pre-exposure prophylaxis (PrEP) for women: Claiming risk and recognizing responsibility to end the AIDS epidemic in New York by Lauren SUCHMAN

“…Introduction: When the drug Truvada was approved for use as pre-exposure prophylaxis (PrEP) to prevent HIV in 2012, it was lauded as the first major advance in HIV prevention in decades and a major step toward reaching the goal of ending the epidemic. …”
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Citrate coated iron oxide nanoparticles: Synthesis, characterization, and performance in protein adsorption by Denise Arrozarena Portilla, Arturo A. Velázquez López, Rosalva Mora Escobedo, Hernani Yee Madeira

“…Magnetic nanoparticles (MNPs) are extensively utilized in biomedicine as part of controlled drug release systems, hyperthermia, and magnetic resonance imaging. …”
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Simultaneous determination of ten nucleosides and bases in Ganoderma by micellar electrokinetic chromatography by Feiya Sheng, Songsong Wang, Xiao Luo, Jianbo Xiao, Linfeng Hu, Peng Li

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Effect of metformin on the level of aqueous humor inflammatory cytokines in patients with cataract by Jiaxi Li, Jiarui Yang, Ziyuan Liu, Xuemin Li

“…Differences in level of AH cytokines were compared between patients using metformin and non-metformin medicine as blood sugar control drug for T2DM and age-related cataract patients without T2DM. …”
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RIPK1 in necroptosis and recent progress in related pharmaceutics by Kunhou Yao, Zhihao Shi, Fengya Zhao, Cong Tan, Yixin Zhang, Hao Fan, Yingzhe Wang, Xingwang Li, Jun Kong, Qun Wang, Dingxi Li

“…The N-terminal kinase domain of RIPK1 is significant in the induction of cell death and can be used as a vital drug target for inhibitors. In this paper, we outline the pathways of necroptosis and the role RIPK1 plays in them and suggest that targeting RIPK1 in therapy may help to inhibit multiple cell death pathways.…”
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Effects of intravaginal curcumin gels combined with electroporation on vulvovaginal candidiasis by Yizhi Zhang, Xiao Chen, Jing Dai, Chenyun Wang, Shan Ma, Lina Du

“…Results: Electroporation increased the transmucosal permeability of the model drug, doxorubicin and improved the antifungal effects of curcumin. …”
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Using tree-based models to identify factors contributing to trait negative affect in adults by Catalina Cañizares, Yvonne Gómez-Maquet, Eugenio Ferro, Carlos Arturo Torres, Diana María Agudelo, Gabriel Odom

“…Objective Determine whether maladaptive cognitive schemas, attributional style, childhood adversity, and lifestyle factors (including alcohol and drug use and physical activity) could effectively predict negative affect (NA) in adults. …”
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The Efficacy of Flupentixol-Melitracen in the Adjuvant Therapy of Ulcerative Colitis in the Chinese Population: A Meta-Analysis by Xiaoqian Zhou, Lei Zhao, Ping Yang, Yaxi Chen, Xiong Z. Ruan

“…Our results suggested that the efficacy of flupentixol-melitracen in the adjuvant therapy of ulcerative colitis is better than traditional drug treatments.…”
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Identification of the circRNA-miRNA-mRNA Regulatory Network in Bladder Cancer by Bioinformatics Analysis by Jiancheng Lv, Ping-an Chang, Xin Li, Xiao Yang, Jie Han, Hao Yu, Zijian Zhou, Haiwei Yang, Pengchao Li, Jiexiu Zhang, Qiang Lu

“…The outstanding genes (CDCA4, GATA6, LATS2, RHOB, ZBTB4, and ZFPM2) also interacted with numerous drugs, indicating their potency as biomarkers and drug targets. …”
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Topical steroids as alternative to systemic hormonal treatment for inflammatory bowel diseases in pediatric practice by E. N. Fedulova, O. V. Shumilova, O. V. Fedorova, O. A. Tutina, G. V. Medyantseva

“…The article presents description of clinical case of successful application of budesonide according to determined goal.Conclusion. Budenofalk® can be a drug of choice in patients with hormone-dependent IBD, and at high risk of complications and severe side effects of systemic CS.…”
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Determination of Scopolamine Distribution in Plasma and Brain by LC-MS/MS in Rats by Juan Chen, Anjing Lu, Daopeng Tan, Qianru Zhang, Yanliu Lu, Lin Qin, Yuqi He

“…This study aimed to develop a simple, sensitive, and selective LC-MS/MS method for the determination of the content and distribution of scopolamine in rat plasma and brain after drug administration. In our study, sample pretreatment consisted of protein precipitation with acetonitrile followed by nitrogen blow concentration. …”
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Hepatitis B Virus (HBV) Genotypes in an Ecuadorian Population: A Preliminary Study by Miguel Moncayo, Enrique Teran, Bernardo Gutierrez, Jorge Reyes, Johanna Cortez, Rodrigo Tobar, Gabriela Yerovi, Marcia Robalino, Ana Aguilar, Daniel Garzon-Chavez

“…The findings can inform antiviral drug effectivity studies specific to HBV genotypes prevalent in South America.…”
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Nurses’ Knowledge of Palliative Care in the Pneumological Hospital by Inarvis Medina González, Elicerio Jorge Chacón Reyes, Odalys Tomaida Hernández Quintero

“…The variables analyzed were years of experience, educational level, knowledge of defining aspects of palliative care, pain management, intervention for control of dyspnea, criteria for drug administration and choice of route of administration as well as nurses’ perception of their knowledge of palliative care. …”
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Efficient voltammetric platform combining a molecularly imprinted polymer and silver-nanoparticle-decorated black phosphorus nanosheets for selective determination of Gatifloxacin by Jingtao Wu, Yonghui Xia, Tianyu Wang, Yafeng Zhang, Guangli Li

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Magnetic core‐shell Fe3O4@TiO2 nanocomposites for broad spectrum antibacterial applications by Nisha Rani, Brijnandan S. Dehiya

“…The TiO2 shell is primarily intended for use as a biocompatible and antimicrobial carrier for drug delivery and possible other applications such as wastewater remediation purposes because of its known antibacterial and photocatalytic properties. …”
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COVID-19 clinical presentation, management, and epidemiology: a concise compendium by David P. Maison, David P. Maison, Hawi Tasissa, Amelia Deitchman, Michael J. Peluso, Youping Deng, F. DeWolfe Miller, Timothy J. Henrich, Mariana Gerschenson

“…Coronavirus Disease 2019, caused by severe acute respiratory coronavirus 2, has been an ever-evolving disease and pandemic, profoundly impacting clinical care, drug treatments, and understanding. In response to this global health crisis, there has been an unprecedented increase in research exploring new and repurposed drugs and advancing available clinical interventions and treatments. …”
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Advances in antiviral strategies targeting mosquito-borne viruses: cellular, viral, and immune-related approaches by Ayyaz Khan, Zakirullah, Shahid Wahab, Seong-Tshool Hong

“…Additionally, it explores immunomodulatory therapies to enhance antiviral responses and emphasizes the potential of drug repurposing, bioinformatics, artificial intelligence, and deep learning in identifying novel antiviral candidates. …”
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Patterns of pregabalin prescribing in four German federal states: analysis of routine data to investigate potential misuse of pregabalin by Ronja Flemming

“…Unintended coprescription of drugs with addictive potential might occur when care is insufficiently coordinated.Design Secondary data analysis of linked data from three regional sickness funds in Germany (AOK) for the years 2014–2016.Setting Ambulatory and hospital care sector in four German federal states.Methods On the basis of routine data, patients who received at least three prescriptions of pregabalin were identified and classified into patients prescribed pregabalin as recommended and those dispensed with a higher than recommended dose (>600 mg/day). …”
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Assessment of Protective Effects of Carvacrol on Haloperidol-Induced Oxidative Stress and Genotoxicity in Human Peripheral Blood Lymphocytes by Ehsan Zamani, Alireza Ahmadi Shad, Hediye Fatemi, Saba Mahboubi, Azadeh Motavallian, Mehdi Evazalipour

“…Haloperidol is a first-generation antipsychotic drug that has several indications in a wide range of mental conditions. …”
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Resistin Activates p65 Pathway and Reduces Glycogen Content through Keratin 8 by Fengyun Wen, Qiao Xia, Hui Zhang, Haipeng Shia, Amin Rajesh, Yanling Wu, Yi Yang, Zaiqing Yang

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