Development and evaluation of orally disintegrating tablets containing the mosapride resin complex by Wu Tong, Wang Guanhua, Shi Caihong, Li Jinghan, Zhao Na, Dong Zihao, Pan Weisan, Zhang Xiangrong

“…The pH dependence of mosapride release from the tablet decreased drug dissolution in simulated saliva, whereas it promptly released in the pH 1.0 solution. …”
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Insights Into Genetic Variations of the OCT1 Gene in Metformin Poor Responders Among Bangladeshi Type 2 Diabetic Patients by Rokeya Begum, Arindita Das, Md. Jahangir Alam, Gazi Nurun Nahar Sultana

“…Metformin is the most widely prescribed drug for the treatment of Type 2 diabetes mellitus (T2DM), but its response varies from person to person. …”
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Single Standard Substance for the Simultaneous Determination of Eleven Components in the Extract of Paeoniae Radix Alba (Root of Paeonia lactiflora Pall.) by Menglan Shen, Qiaoyan Zhang, Luping Qin, Binjun Yan

“…Paeoniae Radix Alba (PRA), an herbal drug produced from the root of Paeonia lactiflora Pall., is widely used in many herbal medicine prescriptions/preparations. …”
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Improved 11α-hydroxycanrenone production by modification of cytochrome P450 monooxygenase gene in Aspergillus ochraceus by Li Qianqian, Shi Li, Liu Yingying, Guan Shimin, Zhang Shuo, Cai Baoguo, Rong Shaofeng

“…Eplerenone is a drug that protects the cardiovascular system. 11α-Hydroxycanrenone is a key intermediate in eplerenone synthesis. …”
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FBXL16 Promotes Endometrial Progesterone Resistance via PP2AB55α/Cyclin D1 Axis in Ishikawa by Haoen Liu, Li Han, Liyan Zhong, Xiaodan Zhuang, Yan Peng

“…F-box proteins are essential components of the E3 ubiquitin ligases which are involved in the regulation of almost all life activities such as cell cycle, proliferation, and apoptosis, which have become an important research and drug target. However, there are few studies on F-box and leucine-rich repeat protein 16 (FBXL16) in endometrial carcinoma. …”
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Clinical Utility of Zuranolone for Postpartum Depression: A Narrative Review by Giannopoulos A, Singh J, Deligiannidis KM

“…Zuranolone is the first US Food and Drug Administration approved oral antidepressant for adult females with PPD. …”
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Governing the boundary: between socio-environmental vulnerability and state capacity in Temajuk Village, Indonesia by Alfath Bagus Panuntun El Nur Indonesia, Defila Priana Falarima, Said Khaidir, Ari Surida, Nur Muliasari MS, Tara Charissa Oktavia S

“…The findings exposed potential national threats caused by geographic isolation, and porous borders that facilitate illicit activities, such as drug and alcoholic drinks smuggling, with serious social consequences, including youth delinquency, early marriage, declining education levels, and increased health risks, such as the spread of HIV/AIDS. …”
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Plant Sources, Extraction Methods, and Uses of Squalene by M. Azalia Lozano-Grande, Shela Gorinstein, Eduardo Espitia-Rangel, Gloria Dávila-Ortiz, Alma Leticia Martínez-Ayala

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Stray dogs as carriers of E. coli resistant strains for the retracted and re-emerged antibiotic colistin, based on the mcr-1 gene presence by Ioannis Tsakmakidis, Anastasia Parisi, Dimitrios K. Papadopoulos, Maria V. Alvanou, Konstantinos V. Papageorgiou, Evanthia Petridou, Ioannis A. Giantsis

“…Reports of resistance to colistin, an antibiotic that is considered a last resort drug against resistant Gram-negative bacteria, have been increasing over the last years. …”
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Burden of scabies in a Ghanaian penitentiary. by Yaw Ampem Amoako, Michael Ntiamoah Oppong, Dennis Odai Laryea, Gloria Kyem, Solomon Gyabaah, Abigail Agbanyo, Bernadette Agbavor, Nana Konama Kotey, Irene Dzathor, Felicia Owusu-Antwi, Kingsley Asiedu, Richard Odame Phillips, Ymkje Stienstra

“…Therefore, we aimed to assess the burden of scabies and ascertain if prevalence was high enough to warrant mass drug administration (MDA) with ivermectin in a medium security prison in central Ghana.…”
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Integrated Network Pharmacology and Gut Microbiota Study on the Mechanism of Huangqin Decoction in Treatment Diabetic Enteritis by Xiaomin Xu, Cheng Fang, Fang Lu, Shumin Liu

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In Vitro and In Vivo Wound Healing Activity of Astragalus floccosus Boiss. (Fabaceae) by Fatemeh Akbari, Mohammad Azadbakht, Ali Bagheri, Lale Vahedi

“…Furthermore, in vitro drug release of Astragalus ointment showed a stationary line during 24 h and 0.14 mg/ml of flavonoid penetrated the skin. …”
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Divergent alkynylative difunctionalization of amide bonds through C–O deoxygenation versus C–N deamination by Feng Liu, Xueyuan Yan, Fangfang Cai, Wenjuan Hou, Jianyu Dong, Shuang-Feng Yin, Genping Huang, Tieqiao Chen, Michal Szostak, Yongbo Zhou

“…Abstract The transformation and utilization of amides are significant in organic synthesis and drug discovery. Here we demonstrate a divergent alkynylative difunctionalization of amides in a single transformation. …”
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Microbubble dynamics in brain microvessels. by James H Bezer, Paul Prentice, William Lim Kee Chang, Sophie V Morse, Kirsten Christensen-Jeffries, Christopher J Rowlands, Andriy S Kozlov, James J Choi

“…Focused ultrasound stimulation of microbubbles is being tested in clinical trials for its ability to deliver drugs across the blood-brain barrier (BBB). This technique has the potential to treat neurological diseases by preferentially delivering drugs to targeted regions. …”
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Economic Evaluation of Fidaxomicin for the Treatment of Clostridium Difficile Infection (C. difficile-associated diarrhoea) in Ireland by Anke van Engen, Montserrat Casamayor, Fidelma Loftus, Martin Coen, Andy Garnham, Maureen Watt, Larry Lacey

“…Based on this analysis, fidaxomicin has received reimbursement for CDI treatment under the High Tech Drug Scheme in Ireland.…”
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Factors Affecting Compliance of Infection Control Measures among Dental Radiographers by Maram Alakhras, Dana S. Al-Mousa, Arwa Mahasneh, Amani G. AlSa’di

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Role of Intestinal Transit in the Pathogenesis of Gallbladder Stones by R Hermon Dowling, Martin J Veysey, Stephen P Pereira, S Hyder Hussaini, Linzi A Thomas, John AH Wass, Gerard M Murphy

“…Therefore, in OT-treated patients and other groups at high risk of developing stones, it may be possible to prevent GBS formation with the use of intestinal prokinetic drugs.…”
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Biodegradable triboelectric nanogenerator as a implantable power source for embedded medicine devices by Gang Jian, Shangtao Zhu, Xiao Yuan, Shengqiao Fu, Ning Yang, Chao Yan, Xu Wang, Ching-Ping Wong

“…The BI-TENG was connected to an interdigital electrode to generate an electric field, which stimulated the accelerated release of doxorubicin (DOX) from red blood cells in targeted drug delivery systems. After stopping the electric field, the release of DOX normalized, facilitating the precise killing of cancer cells. …”
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Quantitative Detection of miRNA-21 Expression in Tumor Cells and Tissues Based on Molecular Beacon by Qingxin Liu, Jialong Fan, Chuang Zhou, Liqun Wang, Bin Zhao, Haibin Zhang, Bin Liu, Chunyi Tong

“…As a new tumor marker, the microRNA-21 (miRNA21) level can provide important information for early diagnosis, drug treatment, and prognosis of gastric cancer. …”
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4-Aminoquinoline as a privileged scaffold for the design of leishmanicidal agents: structure–property relationships and key biological targets by Angel H. Romero, Francisco Delgado

“…At the moment, there are neither approved vaccines nor effective drugs for the treatment of human leishmaniasis for any of its three typical clinical manifestations, and, importantly, the drugs of clinical use have several side effects, require complex administration regimens, present high cost, and are ineffective in many populations due to pathogen resistance. …”
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