Dextran-Polyacrylamide as Matrices for Creation of Anticancer Nanocomposite by G. Telegeev, N. Kutsevol, V. Chumachenko, A. Naumenko, P. Telegeeva, S. Filipchenko, Yu. Harahuts

“…Drug targeting to specific organs and tissues is one of the crucial endeavors of modern pharmacotherapy. …”
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Methotrexate and Valproic Acid Affect Early Neurogenesis of Human Amniotic Fluid Stem Cells from Myelomeningocele by Vardine Sahakyan, Enrico Pozzo, Robin Duelen, Jan Deprest, Maurilio Sampaolesi

“…In conclusion, we setup a human cell model of MMC to study early neurogenesis and for drug screening purposes. We also proposed the detection of early neural gene expression in AFSCs as an additional MMC diagnostic tool.…”
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Knowledge and Attitude of Pharmacy Students Regarding Timing of Prescribed Medicines Administration: Chronotherapy by Humayun Mirza, Ayesha Mansoor, Farheen Ahmad, Warda Idrees, Talmeez Zeb, Amir Naveed

“…The introduction highlights the significance of considering the optimal time for drug administration in patient care, emphasizing the impact of biological rhythms on therapeutic outcomes. …”
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Cytotoxic and Apoptotic Effects of Different Extracts of Artemisia turanica Krasch. on K562 and HL-60 Cell Lines by Zahra Tayarani-Najaran, Mahla Sareban, Atefeh Gholami, Seyed Ahmad Emami, Mahdi Mojarrab

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Biological Evaluation of Pupalia lappacea for Antidiabetic, Antiadipogenic, and Hypolipidemic Activity Both In Vitro and In Vivo by Vivek Kumar, Parag Jain, Kalpana Rathore, Zabeer Ahmed

“…Antiadipogenic activity was determined by in vitro method on 3T3-L1 cell line in comparison to simvastatin as reference drug. Result. The extract showed significant fall in fasting serum glucose (FSG), that is, 234.68 and 211.61 mg/dL, in STZ induced diabetic animals for dose groups AS001 and AS002, respectively. …”
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Acorus shannai (Acoraceae), a new species from Southern China by Zhuo Cheng, Xinyu Liu, Nianting Yu, Weizhe Chen, Haofeng Zhao, Feifei Li, Chunlin Long

“…The recognition of A. shannai is not only important for the species diversity and phylogenetic relationship of Acorus, but also can avoid the drug safety caused by using other Acorus species as A. shannai to eat and promote the conservation of A. shannai resources.…”
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Effects of local rosuvastatin/hyaluronan hydrogel on post-orthodontic relapse reduction in rabbits: Histological and immunohistochemical study by Saba N. Yaseen, Hakam H. Al‑Fakhry, Mohanad Y. Saleh

“…One of the most novel approaches to reducing post-orthodontic relapse is the local delivery of osteogenic agents by drug carriers. This study evaluated the effect of a local injection of rosuvastatin (RSV) carried by hyaluronan hydrogel (HAH) on alveolar bone regeneration. …”
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Circulatory Support with Venoarterial ECMO Unsuccessful in Aiding Endogenous Diltiazem Clearance after Overdose by Erin N. Frazee, Sarah J. Lee, Ejaaz A. Kalimullah, Heather A. Personett, Darlene R. Nelson

“…In cardiovascular collapse from diltiazem poisoning, extracorporeal membrane oxygenation (ECMO) may offer circulatory support sufficient to preserve endogenous hepatic drug clearance. Little is known about patient outcomes and diltiazem toxicokinetics in this setting. …”
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A novel lidocaine-chitosan-barium titanate microemulsion gel for prolonged local anesthesia: An in vitro study by Qiao Xiaoru, Li Ling

“…Lidocaine/chitosan with BaTiO3 nanoparticles as a carrier achieved over 84% drug release, whereas the lidocaine/chitosan without the BaTiO3 nanoparticles only reached 52% cumulative release. …”
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Antioxidant Activity, Enzyme Inhibition Potentials, and Phytochemical Profiling of Premna serratifolia L. Leaf Extracts by Adelina Simamora, Adit W. Santoso, Kris H. Timotius, Ika Rahayu

“…Premna serratifolia leaves can be an appropriate choice for the development of nutraceutical and drug preparations.…”
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Camptocormia in Parkinson's Disease by Kazuo Abe, Yutaka Uchida, Masaru Notani

“…There were no significant differences in age, duration, severity, and drug dose between patients with and without camptocormia. …”
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siRNA therapeutics for effective management of rheumatoid arthritis by Vishakha R. Chakole, Tathagata Dutta, Priyankar Sen

“…This extended half-life enables a sustained, slow release of the drug, contributing to superior recovery from pain and inflammation associated with conditions like RA.…”
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(5E,7E)-4,5,6 Trihydroxy-3-(hydroxymethyl)tetrahydro-2H-pyran-2-ylheptadeca-5,7-dienoate from Euclea crispa (L.) Inhibits Ovarian Cancer Cell Growth by Controlling Apoptotic and Me... by Chella Perumal Palanisamy, Bo Cui, Hongxia Zhang, Selvaraj Jayaraman, Ponnulakshmi Rajagopal, Vishnu Priya Veeraraghavan

“…The in vivo studies and attempts will pave way for this compound to be an effective drug hereafter.…”
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Effect of 3-hydrazinylquinoxaline-2-thiol hydrogel on skin wound healing process in diabetic rats by Jehan Barakat Alamre, Huda Alkreathy, Ahmed S. Ali, Abdelbagi Alfadil, Sahar S. Alghamdi

“…In silico study indicated a favorable drug-like properties and toxicity profile. The present work showed that 3-hydrazinylquinoxaline-2-thiol holds great potential for the treatment of diabetic wounds.…”
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Structure and function of a near fully-activated intermediate GPCR-Gαβγ complex by Maxine Bi, Xudong Wang, Jinan Wang, Jun Xu, Wenkai Sun, Victor Ayo Adediwura, Yinglong Miao, Yifan Cheng, Libin Ye

“…Abstract Unraveling the signaling roles of intermediate complexes is pivotal for G protein-coupled receptor (GPCR) drug development. Despite hundreds of GPCR-Gαβγ structures, these snapshots primarily capture the fully activated complex. …”
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The protective effect of coadministration of coenzyme Q10 and vitamin E on myopathy induced by simvastatin in rats by Omar Ammar Hashim, Intesar Tarik Numan, Nadia Hameed Mohammed

“…The combination group showed a superior protective effect than either drug alone. Treatment with vitamin E and CoQ10 showed mild vacuolation and cytoplasm with focal splitting and fragmentation of muscle fibers, scattered central nuclei, and eosinophilic cytoplasm. …”
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Elucidating the potential of EGFR mutated NSCLC and identifying its multitargeted inhibitors by Anakha D. Rajeeve, Ramasamy Yamuna, P. K. Krishnan Namboori

“…Since curcumin and CB[2]UN support various medicinal applications in drug delivery and design, we investigated the effect of curcumin and CB[2]UN-based drugs in controlling EGFR-mutant NSCLC through a dodecagonal computational approach. …”
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Extracellular Cold-Inducible RNA-Binding Protein and Hemorrhagic Shock: Mechanisms and Therapeutics by Naureen Rashid, Zhijian Hu, Asha Jacob, Ping Wang

“…We also share our more newly developed anti-eCIRP agents with the eventual goal of producing drug therapies to mitigate organ damage, reduce mortality, and improve patient outcomes related to hemorrhagic shock. …”
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A Rare Case of Grey Zone Lymphoma Successfully Treated with Brentuximab Vedotin and R-CHP Chemotherapy by Rajiv M. Mallipudi, Lance Alquran, Vishnu A. Shenoy, Lori A. Leslie, John A. Conti

“…Brentuximab vedotin (BV) is an anti-CD30 antibody drug conjugate that has established efficacy in relapsed/refractory Hodgkin and some T-cell lymphomas. …”
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A Case of Severe Hydroxychloroquine-Induced Retinal Toxicity in a Patient with Recent Onset of Renal Impairment: A Review of the Literature on the Use of Hydroxychloroquine in Rena... by Rajen Tailor, Ibrahim Elaraoud, Peter Good, Monique Hope-Ross, Robert A. H. Scott

“…Should renal impairment develop, either the drug should be stopped or the dose reduced with close monitoring of visual function by an ophthalmologist.…”
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