Food recalls: An unnecessary and preventable factor in food waste by Rubén Morawicki

“…Depart­ment of Agriculture (USDA) and the U.S. Food and Drug Administration (FDA) into three classes based on the severity of health risks, with Class I being the most severe; a Class I recall is for defec­tive products that can cause severe health effects or death (FDA, 2024, p. 7-1; UDSA Food Safety and Inspection Service [USDA FSIS], 2024-b). …”
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Pulmonary Artery Pseudoaneurysm: A Rare Cause of Fatal Massive Hemoptysis by Himaja Koneru, Sreeja Biswas Roy, Monirul Islam, Hesham Abdelrazek, Debabrata Bandyopadhyay, Nikhil Madan, Pradnya D. Patil, Tanmay S. Panchabhai

“…We present a case of a 28-year-old woman with necrotizing pneumonia from intravenous drug use who ultimately died from massive hemoptysis and shock after a ruptured PAPA.…”
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Simultaneous determination of macrolides in water samples by solid-phase extraction and capillary electrophoresis by Pavlović Dragana Mutavdžić, Babić Sandra, Čizmić Mirta, Sertić Miranda, Pinušić Tea

“…Good linearity was obtained in the range of 0.3–30 mg L−1 depending on the drug, with correlation coefficients higher than 0.9958 in all cases except clarithromycin (0.9873). …”
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Exploring the association between khat use and psychiatric symptoms: a systematic review by Betsy Edwards, Naomi Atkins

“…Objectives Consumption of the drug khat is high across East Africa and the South-Western Arabian Peninsula despite evidence for its adverse psychiatric effects. …”
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CDCA7 enhances STAT3 transcriptional activity to regulate aerobic glycolysis and promote pancreatic cancer progression and gemcitabine resistance by Dijie Zheng, Yazhu Deng, Lu Deng, Zhiwei He, Xinghao Sun, Yanyu Gong, Binbin Shi, Deqin Lu, Chao Yu

“…CDCA7 overexpression promoted PC cell proliferation, migration, and invasion, and increased resistance to the chemotherapy drug gemcitabine, possibly through enhanced aerobic glycolysis. …”
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Comparative bioavailability of two oral formulations of clopidogrel: Determination of clopidogrel and its carboxylic acid metabolite (SR26334) under fasting and fed conditions in h... by Brvar Nina, Lachance Sylvain, Lévesque Ann, Breznik Marjanca, Cvitkovič Marčič Lea, Merslavič Mateja, Grabnar Iztok, Mateovič-Rojnik Tatjana

“…Assessment of bioequivalence was based upon measurement of plasma concentrations of the parent drug, clopidogrel, and its major (inactive) metabolite, clopidogrel carboxylic acid, using improved methanol-free extraction. …”
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Substituted piperazine conjugated to quinoline-thiosemicarbazide as potent α-glucosidase inhibitors to target hyperglycemia by Mehran Ghasemi, Mohammad Mahdavi, Maryam Dehghan, Mohammadreza Eftekharian, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Aida Iraji, Ahmed Al-Harrasi

“…Among the synthesized derivatives, the 2,5-dimethoxy phenyl substitution (7j) exhibited the most potent activity with an IC50 value of 50.0 µM, demonstrating a 15-fold improvement compared to the standard drug acarbose. Kinetic studies identified compound 7j as a competitive inhibitor, with a K i value of 32 µM. …”
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PPARγ Expression and Function in Mycobacterial Infection: Roles in Lipid Metabolism, Immunity, and Bacterial Killing by Patricia E. Almeida, Alan Brito Carneiro, Adriana R. Silva, Patricia T. Bozza

“…Tuberculosis continues to be a global health threat, with drug resistance and HIV coinfection presenting challenges for its control. …”
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Natural compounds in the management of polycystic ovary syndrome: a comprehensive review of hormonal regulation and therapeutic potential by Jingyi Yuan, Zhenmin Li, Yongjiang Yu, Xiuge Wang, Yunyun Zhao

“…However, these treatments may often lead to adverse effects, and most medications prescribed for PCOS are used off-label and have not secured approval from the U.S. Food and Drug Administration specifically for this condition. …”
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Prostate-Specific Membrane Antigen-Based Therapeutics by Naveed H. Akhtar, Orrin Pail, Ankeeta Saran, Lauren Tyrell, Scott T. Tagawa

“…Anti-PSMA monoclonal antibody-drug conjugates have also been developed with completed and ongoing early-phase clinical trials. …”
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Challenges and Barriers Faced by People with TB and Healthcare Workers Providing TB Care and Management – A Qualitative Study by S. Suseendar, Akhil Dhanesh Goel, T. Pritish Baskaran, V. R. Rehana, Pankaj Bhardwaj, Manoj Kumar Gupta, S. Srikanth, Suman Saurabh

“…Conclusion: Communication between providers and people with TB must be improved to improve the drug adherence and satisfaction of the end user. …”
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Methodological proposal with an interdisciplinary approach for teaching learning content theory of the pharmacological receptor in the medical career by Yeny Dueñas Pérez, Ana María Ramos Cedeño, Belkis Barrios Romero, Alicia del Rosario Ramírez Pérez, Yacelis Dahilet Cisneros Nápoles, Mirtha Amarilis Hernández López

“…<p><strong>Background:</strong> in therapeutic decision-making, the importance of knowledge of the drug receptor theory content is recognized; however, there is a lack of proposals from interdisciplinarity, which is useful as reference for teachers to improve the teaching of this process.…”
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Self‐Driving Lab for Solid‐Phase Extraction Process Optimization and Application to Nucleic Acid Purification by Sebastian Putz, Jonathan Döttling, Tim Ballweg, Andre Tschöpe, Vitaly Biniyaminov, Matthias Franzreb

“…Sorptive bioprocesses are the basis for numerous biotechnological applications such as enzyme immobilization, biosensors, controlled drug delivery, water treatment, and molecular purification. …”
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Treatment with Herbal Formula Extract in the hSOD1G93A Mouse Model Attenuates Muscle and Spinal Cord Dysfunction via Anti-Inflammation by Eun Jin Yang, Sun Hwa Lee, Mudan Cai

“…Currently, there is no effective drug for treating patients with ALS. Herbal medicine, used to treat various diseases, has multitarget effects and does not usually induce side effects. …”
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Fast and Simple LC-MS/MS Method for Rifampicin Quantification in Human Plasma by Žane Temova Rakuša, Robert Roškar, Anita Klančar Andrejc, Tina Trdan Lušin, Nataša Faganeli, Iztok Grabnar, Aleš Mrhar, Albin Kristl, Jurij Trontelj

“…The proposed method was successfully applied to rifampicin quantification in 340 patients’ plasma samples, thus demonstrating its suitability for both therapeutic drug monitoring and pharmacokinetic analysis.…”
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Hyperuricemia-induced complications: dysfunctional macrophages serve as a potential bridge by Wenyi Gu, Wenyi Gu, Jiajing Zhao, Yu Xu, Yu Xu, Yu Xu

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Multiple Tophaceous Gout of Hand with Extensor Tendon Rupture by Haruki Tobimatsu, Masanori Nakayama, Yu Sakuma, Hitoshi Imamura, Koichiro Yano, Hiroko Itagaki, Katsunori Ikari

“…A 45-year-old man presented with painless subcutaneous masses bilaterally on his hands and loss of motion or contracture of the fingers. Initially, drug therapy to reduce the serum uric acid was administered and was expected to reduce the tophi. …”
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Redefining the Mode of HIV Transmission through Analysis of Risk Attribution among the Reported HIV Cases from 1993 to 2021 in Bhutan by Lekey Khandu, Ngawang Choida, Jurmi Drukpa, Dolley Tsehring, Sonam Wangdi

“…Of the 81.94% high-risk heterosexuals, 41.08% acquired through sex workers and clients of sex workers, 27.99% from HIV-infected persons, 12.64% from sex work, and 0.23% from injecting drug use. Conclusions. This study has shed some light on a gradual epidemic shift from the current perceived diffused and generalized to the concentrated epidemic among subpopulation groups like female sex workers and their clients.…”
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Efficacy and safety of solifenacin for overactive bladder: An updated systematic review and meta-analysis by I Gede Yogi Prema Ananda, Radika Naufal Hadi Surya, Prima Ardiansah Surya, Alfin Putratama, Dimas Panca Andhika

“…Solifenacin is an antimuscarinic drug that Excels in OAB treatment due to its specific bladder receptor targeting. …”
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Peroxisome Proliferator-Activated Receptors in Female Reproduction and Fertility by Maurizio Vitti, Giovanna Di Emidio, Michela Di Carlo, Gaspare Carta, Andrea Antonosante, Paolo Giovanni Artini, Annamaria Cimini, Carla Tatone, Elisabetta Benedetti

“…Finally, the therapeutic potential of their manipulation through several drugs is also discussed.…”
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