Old and Recent Advances in Life Cycle, Pathogenesis, Diagnosis, Prevention, and Treatment of Malaria Including Perspectives in Ethiopia by Dejen Nureye, Solomon Assefa

“…Lack of clear understanding on the overall biology of Plasmodium has created a challenge in an effort to develop new drugs, vaccines, and preventive methods against malaria. …”
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Percutaneous Coronary Intervention Using the DynamX Sirolimus-Eluting Bioadaptor: 12-Month Clinical and Imaging Outcomes by Mark Webster, Douglas Scott, Madhav Menon, Dougal McClean, Seif El-Jack, Gerard Wilkins, Scott A. Harding

“…In conclusion, this study provides evidence of the safety and performance of the DynamX Bioadaptor with excellent 12-month clinical and 6-month imaging outcomes comparable to best-in-class drug-eluting stents (DES).…”
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The Influence of Palatable Diets in Reward System Activation: A Mini Review by Isabel Cristina de Macedo, Joice Soares de Freitas, Iraci Lucena da Silva Torres

“…The mechanism of neural adaptation triggered by palatable foods is similar to those that have been reported for nondrug addictions and long-term drug use. Thus, this review attempts to describe the potential mechanisms that might lead to highly palatable diets, such as the cafeteria diet, triggering addiction, or compulsion through the reward system.…”
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Clinical and Laboratory Diagnosis of Buruli Ulcer Disease: A Systematic Review by Samuel A. Sakyi, Samuel Y. Aboagye, Isaac Darko Otchere, Dorothy Yeboah-Manu

“…Early diagnosis is crucial to prevent morbid effects and misuse of drugs. We review developments in laboratory diagnosis of BU, discuss limitations of available diagnostic methods, and give a perspective on the potential of using aptamers as point-of-care. …”
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Immunomodulatory effects of Lactiplantibacillus plantarum CCFM8661 + stachyose on cyclophosphamide-induced immunosuppression mice by Weiwei Ma, Hang Sun, Lian Lian, Lidong Guo, Yanyan Wang, Lili Huang

“…This study aims to investigate the immunoregulatory effects of Lactiplantibacillus plantarum CCFM8661 combined with stachyose in cyclophosphamide-induced immunocompromised mice.MethodsMice were divided into the normal control group, model control group (normal saline), positive drug control group (levamisole hydrochloride, 10 mg/kg), and low, medium, and high-dose groups (1.5×105, 1.5×106, and 1.5×107 CFU of Lactiplantibacillus plantarum CCFM8661 + 1.5 mg stachyose). …”
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A Standardized Approach to Quantitative Analysis of Nicotine in e-Liquids Based on Peak Purity Criteria Using High-Performance Liquid Chromatography by Vinit V. Gholap, Leon Kosmider, Matthew S. Halquist

“…Although the Food and Drug Administration (FDA) has recently started regulating e-cigarette products, no limits on nicotine and other ingredients in such products have been proposed. …”
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The meaning of the concept of “crime prevention in the customs sphere” by R. A. Cherkasskyi

“…These are, in particular, drug addiction, alcoholism of the population, popularization of the criminal subculture, prostitution, low level of legal awareness of the population and education in general, shortcomings in the work of public authorities and more.…”
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Neuroprotective Potentials Of Extracts From Moringa Oleifera And Musa Sapientum Against Cadmium Chloride-Induced Neurotoxicity In Rats Cerebri by Adelaja Akinlolu

“…This study evaluated the neuroprotective potential of active drug compounds extracted from Moringa oleifera leaves (MO11) and Musa sapientum suckers (MS06) in cadmium chloride (CdCl2)-induced neurotoxicity in rats. …”
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Literature Study of Formulating and Testing Physical Properties of Hand Sanitizer Preparations of Various Plant Extracts by Susi Yanti, Cory Linda Futri

“…According to the US FDA (Food and Drug Administration) the advantages of hand sanitizers are that they are able to kill germs in a relatively fast time. …”
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Opicapone, a Novel Catechol-O-methyl Transferase Inhibitor, for Treatment of Parkinson's Disease "Off" Episodes by Amnon A. Berger, Ariel Winnick, Jonathan Izygon, Binil M. Jacob, Jessica S. Kaye, Rachel J. Kaye, Elisa E. Neuchat, Adam M. Kaye, Edward S. Alpaugh, Elyse M. Cornett, Andrew H. Han, Alan D. Kaye

“…This paper reviews the seminal and latest evidence in the treatment of PD "off episodes" with the novel drug Opicapone, including efficacy, safety, and clinical indications.…”
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Frequency and Causes of Methotrexate Intolerance and Discontinuation in Rheumatoid Arthritis Patients in Qena Governorate by Sondos Mohammed Sayed, Mohamed Ismail Abdelkareem, Eman Ragab Abdelradi, Wael Abd El-Mohsen Abady

“…Background: Methotrexate (MTX) is a conventional disease-modifying anti-rheumatic drug that has been used as first-line therapy for rheumatoid arthritis (RA), the frequency of MTX side effects and its discontinuation has been documented earlier, although it hasn't been fully investigated yet. …”
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Functional Role of Adult Hippocampal Neurogenesis as a Therapeutic Strategy for Mental Disorders by Heechul Jun, Syed Mohammed Qasim Hussaini, Michael J. Rigby, Mi-Hyeon Jang

“…In this paper, we discuss three major psychiatric disorders, depression, schizophrenia, and drug addiction, in light of preclinical evidence used in establishing the neurobiological significance of adult neurogenesis. …”
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Clopidogrel Protects Endothelium by Hindering TNFα-Induced VCAM-1 Expression through CaMKKβ/AMPK/Nrf2 Pathway by Huabing Yang, Pengjun Zhao, Shiliu Tian

“…Clopidogrel (INN), an oral antiplatelet drug, has been revealed to have a number of biological properties, for instance, anti-inflammation and antioxidation. …”
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Recent Advances in Antimicrobial Resistance: Insights from <i>Escherichia coli</i> as a Model Organism by Zhaoyang Zhang, Minliang Wei, Bin Jia, Yingjin Yuan

“…Key resistance mechanisms are discussed, including drug inactivation, target modification, altered transport, and metabolic adaptation. …”
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Assessment of the Availability and Accuracy of Dosing Devices Packaged with Oral Liquid Medications in the Ho Municipality of Ghana by Yussif Saaka, David M. Nyamadi, Hilda Amekyeh, Adelaide Mensah

“…Administering the right dose of medications is essential in avoiding potentially life-threatening adverse drug reactions. Industry guidelines for manufacturers of oral, over-the-counter, and liquid medications recommend including dose-delivery devices with packaging to limit dosing inaccuracy. …”
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Modulatory effects of rutin on the expression of cytochrome P450s and antioxidant enzymes in human hepatoma cells by Karakurt Sedar

“…Expression of a drug and xenobiotic metabolizing enzymes, cytochrome P450s (CYPs), and antioxidant enzymes can be modulated by various factors. …”
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Clinical characteristics and laparoscopic management experience of primary ovarian leiomyoma by Jiaren Zhang, Rong Zhu, Xiaona Lin

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Medicinal plants mediated the green synthesis of silver nanoparticles and their biomedical applications by Haajira Beevi Habeeb Rahuman, Ranjithkumar Dhandapani, Santhoshini Narayanan, Velmurugan Palanivel, Ragul Paramasivam, Ramalakshmi Subbarayalu, Sathiamoorthi Thangavelu, Saravanan Muthupandian

“…Silver nanotechnology has a big impact on medical applications like bio‐coating, novel antimicrobial agents, and drug delivery systems. This review aims to provide a comprehensive understanding of the pharmaceutical qualities of medicinal plants, as well as a convenient guideline for plant‐based silver nanoparticles and their antimicrobial activity.…”
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Identification of potential COVID-19 main protease inhibitors using structure-based pharmacophore approach, molecular docking and repurposing studies by Daoud Safa, Alabed Shada J., Dahabiyeh Lina A.

“…Therefore, the repurposing of FDA-approved drugs against today’s diseases involves the use of de-risked compounds with potentially lower costs and shorter development timelines. …”
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Acknowledging and addressing real-world challenges to treating immune-related adverse events by Bonnie L Bermas, Mitchell S von Itzstein, David E Gerber, Alexa Meara

“…The latter is complicated by the lack of US Food and Drug Administration-approved irAE treatments that lead to insurance denials, as well as the high cost of biological immunosuppressant therapies. …”
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