Characterization of spoilage bacterial communities in chilled duck meat treated by kojic acid by Wenfu Hou, Qiqi Yue, Wen Liu, Ji Wu, Yang Yi, Hongxun Wang

“…Besides, Brochothrix showed drug resistance and became the dominant bacteria in the kojic acid treated sample after 6-day storage. …”
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A 5-Fluorouracil-Induced Hyperammonemic Encephalopathy Challenged with Capecitabine by Michael Chahin, Nithya Krishnan, Hardik Chhatrala, Marwan Shaikh

“…Suspected etiologies include either elevated levels of the drug due to slower metabolism or accumulation of certain metabolites. …”
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Evaluation of immunomodulatory effects of lamotrigine in BALB/c mice by Abu-Rish Eman Y., Elhayek Shada Y., Mohamed Yehia S., Hamad Islam, Bustanji Yasser

“…Modulation of the immune system has recently been shown to be involved in the pharmacological effects of old antiepileptic drugs and in the pathogenesis of epilepsy. Therefore, the most recent guidelines for immunotoxicological evaluation of drugs were consulted to investigate the immunomodulatory effects of lamotrigine, a newer antiepileptic drug, in BALB/c mice. …”
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Electrophoretic Deposition of Carbon Nanotubes over TiO2 Nanotubes: Evaluation of Surface Properties and Biocompatibility by Jung Eun Park, Il Song Park, Tae Sung Bae, Min Ho Lee

“…Formation of TiO2 nanotubes (TiO2 NTs) on titanium is an interesting surface modification to achieve controlled drug delivery and to promote cell growth. Carbon nanotubes (CNTs) possess excellent chemical durability and mechanical strength. …”
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Generalized Pruritus and Gradual Loss of Vision as the Presenting Complaints of Acute HIV Infection: Management Challenges during COVID-19 Pandemic by Shrebash Paul, S. M. Mahbubur Rahman, Rajibur Rahman, Mahbubur Rahman, Quazi Mamtaz Uddin Ahmed, Rafiqul Alam, Fazle Rabbi Chowdhury

“…This is because of high cross-border mobility (India and Myanmar) of people and increased injection drug abusers amongst youth in the cities and rural areas, HIV can present in many ways, from asymptomatic to advanced disease, including various atypical (generalized itching) and advanced (loss of vision) manifestations. …”
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Cerebral organoids: a promising model in cellular technologies by T. A. Shnaider

“…In addition, we discuss successful implementation of this technology in fundamental and applied research like modeling of different neurodevelopmental disorders and drug screening. Finally, we regard existing problems and prospects for development of human pluripotent stem cell-derived threedimensional cerebral organoid technology.…”
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Identification of egg protein-derived peptides as xanthine oxidase inhibitors: virtual hydrolysis, molecular docking, and in vitro activity evaluation by Zhipeng Yu, Yaxin Cao, Ruotong Kan, Huizhuo Ji, Wenzhu Zhao, Sijia Wu, Jingbo Liu, David Shiuan

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Bioengineering strategies targeting angiogenesis: Innovative solutions for osteonecrosis of the femoral head by Weihong Zhu, Zhenmu Xu, Ding Zhou, Jiankun Xu, Yuchen He, Zhong Alan Li

“…In addition, current therapeutic strategies predominantly only relieve symptoms while disease-modifying ONFH drugs are still under investigation/development. …”
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Fast real-time monitoring of entacapone crystallization and characterization of polymorphs via Raman spectroscopy, statistics and SWAXS by Jednačak Tomislav, Hodzic Aden, Scheibelhofer Otto, Marijan Marijan, Khinast Johannes G., Novak Predrag

“…Crystallization of the drug entacapone from binary solvent mixtures was monitored in situ using a Raman optical probe. …”
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Microbial Surface Treatment of Sand with Sporosarcina pasteurii to Improve the Wind Erosion Resistance in Urmia Lake by Hooshang Katebi, Ahmad Fahmi, Ahad Ouria, Alireza Babaeian Amini, Hossein Samadi Kafil

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Insilico targeting of virus entry facilitator NRP1 to block SARS-CoV2 entry. by Nousheen Bibi, Maleeha Shah, Shahzad Khan, Muhammad Shahzad Chohan, Mohammad Amjad Kamal

“…Therefore, these compounds may serve as potential drug candidates to reduce SARS-CoV-2 infectivity.…”
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A Comparative Systematic Review of the Optimal CD4 Cell Count Threshold for HIV Treatment Initiation by Babatunde Olubajo, Kathryn Mitchell-Fearon, Oluseye Ogunmoroti

“…Optimal therapy initiation would maximize the benefits of these drugs, while minimizing side effects and drug resistance. …”
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Development and Validation of Chlamydia muridarum Mouse Models for Studying Genital Tract Infection Pathogenesis by Yihui Wang, Zixuan Han, Luying Wang, Xin Sun, Qi Tian, Tianyuan Zhang

“…Animal infection models play significant roles in the study of bacterial pathogenic mechanisms and host–pathogen interactions, as well as in evaluating drug and vaccine efficacies. Chlamydia trachomatis is responsible for infections in various mucosal tissues, including the eyes and urogenital, respiratory, and gastrointestinal tracts. …”
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Glycogen Synthase Kinase 3β Promotes Postoperative Cognitive Dysfunction by Inducing the M1 Polarization and Migration of Microglia by Jingjin Li, Chonglong Shi, Zhengnian Ding, Wenjie Jin

“…Lithium chloride (LiCl) is a widely used inhibitor of GSK-3β, and it is also the main drug for the treatment of bipolar disorder. Prophylactic administration of lithium chloride (2 mM/kg) can inhibit the expression of proinflammatory mediators in the hippocampus, reduce the hippocampal expression of NF-κB, and increase both the downregulation of M1 microglial-related genes (inducible nitric oxide synthase and CD86) and upregulation of M2 microglial-related genes (IL-10 and CD206), to alleviate the cognitive impairment caused by orthopedic surgery. …”
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Nuclear Protein 1 Expression Is Associated with PPARG in Bladder Transitional Cell Carcinoma by Chao Lu, Shenglin Gao, Li Zhang, Xiaokai Shi, Yin Chen, Shuzhang Wei, Li Zuo, Lifeng Zhang

“…The Nuclear protein 1 gene was first discovered in acute pancreatitis and functions as an oncogene in cancer progression and drug resistance. However, the role of Nuclear protein 1 in bladder transitional cell carcinoma (BTCC) is still unclear. …”
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Integrative analysis of SEPN1 in glioma: Prognostic roles, functional implications, and potential therapeutic interventions. by Zisong Wang, Danwen Wang, Xuanyu Wang, Yihang Xu, Yunhe Yuan, Yuxin Chen, Zhiqiang Li, Xiaoping Liu

“…We developed an SEPN1-related risk score (SRS) based on SEPN1-related long non-coding RNAs and validated its prognostic value. Drug sensitivity data and connectivity map analysis identified potential anti-glioma drugs based on the SRS.…”
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Effects of Sodium-Glucose Cotransporter-2 Inhibitors on Urine Albumin to Creatinine Ratio in Type 2 Diabetes Mellitus Patients and Medication Care by Dong-Dong Wang, Cun Zhang, Yang Yang, Su-Mei He, Ping Zhu, Xiao Chen

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OM-101 Decreases the Fibrotic Response Associated with Proliferative Vitreoretinopathy by Zeev Dvashi, Keren Ben-Yaakov, Tamir Weinberg, Yoel Greenwald, Ayala Pollack

“…This study suggests that OM-101 is a potentially effective and safe drug for the treatment of PVR patients.…”
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LC-MS/MS Method for Determination of Hydroxychloroquine and Metabolites: Application in a Pharmacokinetic Study by Lili Cui, Zhipeng Wang, Shi Qiu, Mengwei Zhang, Yanping Liu, Fengjing Xu, Xinhua Song, Shouhong Gao, Wansheng Chen

“…Hydroxychloroquine (HCQ) was originally used as an antimalarial and immunomodulation drug. We developed and validated a simple and sensitive ultrahigh performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method for simultaneous quantitation of HCQ and its three metabolites in rat blood, and reported their pharmacokinetic parameters. …”
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Tumour-Associated Transcripts and EGFR Deletion Variants in Colorectal Cancer in Primary Tumour, Metastases and Circulating Tumour Cells by Silke Lankiewicz, Eva Rother, Silke Zimmermann, Christiane Hollmann, Firouzeh Korangy, Tim F. Greten

“…The clinical relevance of circulating tumour cells (CTC) in peripheral blood of patients with colorectal cancer (CRC) has been described as an independent prognostic factor useful to monitor drug effects and clinical status. The aim of the present study was to compare the epidermal growth factor receptor (EGFR) status of primary tumour, related metastases and CTC of patients with CRC. …”
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