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5221
Hormonal Therapies for Acne: A Comprehensive Update for Dermatologists
Published 2025-01-01“…This review aims to update dermatologists on the Federal Drug Administration (FDA)-approved and off-label use of combined oral contraceptives (COC), clascoterone, spironolactone, and emerging hormonal therapies for acne treatment. …”
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5222
Prescription Patterns of Analgesics for Oral Conditions in India - Analysis of Large Medical Audit Data of Outpatients in India’s Private Healthcare Sector
Published 2023-07-01“…This study aimed to analyse the change in prescription rates and patterns of the analgesics prescribed for various oral conditions and to analyse their trends across different age groups and gender to promote rational prescription of drugs and eventually influence regulatory policies. …”
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5223
Analytical Method Development and Validation of Exemestane Tablet by UV Spectrophotometry
Published 2012-01-01“…The optimum conditions for the analysis of the drug were established. The maximum wavelength (λ max) was found to be 246 nm. …”
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5224
Research on Red/Near-Infrared Fluorescent Carbon Dots Based on Different Carbon Sources and Solvents: Fluorescence Mechanism and Biological Applications
Published 2025-01-01“…This article also highlights the applications of R/NIR-CDs in bioimaging, biosensing, phototherapy, and drug delivery. The final section discusses challenges and prospects.…”
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5225
Effects of Pentoxifylline in a Rat Model of Manganism: Evaluation of the Possible Toxicity
Published 2021-01-01“…It was found that PTX supplementation (300 mg/kg, i.p.) deteriorated the Mn-induced locomotor deficit. This drug also increased the Mn brain accumulation as well as reactive oxygen species (ROS) and lipid peroxidation products in the manganism rat model. …”
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5226
Poststroke Cell Therapy of the Aged Brain
Published 2015-01-01“…Stem cell based therapy is a promising approach to promote neuroregeneration after brain injury and can be potentiated when combined with supportive pharmacological drug treatment, especially in the aged. However, the mechanism of action for a particular grafted cell type, the optimal delivery route, doses, or time window of administration after lesion is still under debate. …”
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5227
Photobiomodulation: An Effective Approach to Enhance Proliferation and Differentiation of Adipose-Derived Stem Cells into Osteoblasts
Published 2021-01-01“…Photobiomodulation (PBM) improves ADSC differentiation and proliferation along with reducing clinical difficulties such as treatment failures to common drug therapies and late initiation of treatment. …”
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5228
Aloe Vera Extract-Mediated CuO NPs as Catalysts for the Synthesis of 4-Hydroxy-3-Methoxybenzaldehyde-Connected Piperidine Derivatives and Their Antibacterial Activity
Published 2023-01-01“…Finally, we concluded the compounds 2c and 2d have strong antibacterial activity and can be used as antibacterial drugs in the future.…”
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5229
Identification of therapeutic targets for Alzheimer’s Disease Treatment using bioinformatics and machine learning
Published 2025-01-01“…Furthermore, Noscapine, PX-316, and TAK-901 were selected as potential therapeutic drugs for AD based on PLCB1. This research provides a comprehensive and reliable method for the discovery of AD therapeutic targets and the construction of diagnostic models, offering important insights and directions for future AD treatment strategies and drug development.…”
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5230
Use of Artemisinin- Combination Therapies in Port Harcourt
Published 2013-07-01“…The respondents that took artemisinin based combination drugs were 230 (32.1%), those that took artesunate only were 174 (24.3%), those that took chloroquine were 101 (14.1%) while those that took sulphadoxine/pyrimethamine were 140 (19.5%) while 72 (10%) took other antimalarial drugs. …”
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5231
Assessment of Patients’ Adherence to Antiepileptic Medications at Dessie Referral Hospital, Chronic Follow-Up, South Wollo, Amhara Region, North East Ethiopia
Published 2018-01-01“…And in the majority of patients with epilepsy, antiepileptic drugs effectively control their illness. However, more than 30% of people with epilepsy do not attain full seizure control, even with the best available treatment regimen. …”
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5232
Computational Role of Autocatalytic Chemical Reaction in the Dynamics of a Ternary Hybrid Nanofluid Past a Rotating Stretching Surface
Published 2024-01-01“…Due to its superior thermal conductivity and efficient thermal management, ternary nanofluids play a crucial role in electronic advance cooling systems, solar thermal collectors, managing efficiency of thermal exchangers, targeted drug delivery systems, and various technologies. …”
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5233
Investigation of catechin’s anti-inflammatory activity: A bioinformatics and molecular docking study
Published 2024-12-01“…As a country with rich biodiversity, Indonesia offers numerous phytochemicals with potential for drug development, including catechin, a natural compound with anti-inflammatory properties. …”
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5234
Multidrug Resistance and Plasmid Profiles of Escherichia coli Isolated from Lebanese Broiler Farms
Published 2023-01-01“…There was no significant association between the number of plasmids per isolate and resistance to a particular drug. Nevertheless, the presence of specific plasmids, namely, the 2.2 or 7.7 kbp sized ones, was strongly correlated to Quinolones or Trimethoprim resistance, respectively. …”
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5235
Decitabine-Induced Changes in Human Myelodysplastic Syndrome Cell Line SKM-1 Are Mediated by FOXO3A Activation
Published 2017-01-01“…Currently, the recommended treatment for patients with high-risk MDS is the methylation agent decitabine (DAC), a drug that can induce the reexpression of silenced tumor suppressor genes. …”
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5236
Stability-Indicating RP-HPLC Method for Simultaneous Estimation of Enrofloxacin and Its Degradation Products in Tablet Dosage Forms
Published 2015-01-01“…The degraded products were well resolved from the main active drug and also from known impurities within 65 minutes. …”
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5237
Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1
Published 2013-01-01“…These findings indicated that PD might be an effective antisepsis drug.…”
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5238
Urinary bacteriophage cooperation with bacterial pathogens during human urinary tract infections supports lysogenic phage therapy
Published 2025-02-01“…Abstract Despite much promise in overcoming drug-resistant infections, clinical studies of bacteriophage antibacterial therapy have failed to show durable effectiveness. …”
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5239
General Approach to Identifying Potential Targets for Cancer Imaging by Integrated Bioinformatics Analysis of Publicly Available Genomic Profiles
Published 2011-03-01“…Molecular imaging has moved to the forefront of drug development and biomedical research. The identification of appropriate imaging targets has become the touchstone for the accurate diagnosis and prognosis of human cancer. …”
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5240
Development of Thermoresponsive Composite Hydrogel Loaded with Indocyanine Green and Camptothecin for Photochemotherapy of Skin Cancer After Surgery
Published 2025-01-01“…Although regimens such as chemotherapy and/or immunotherapy are often administered following surgical treatments, the patients may suffer from severe side effects, drug resistance, and/or high cost during treatments, indicating that the development of an effective and safe modality for skin cancer after surgery is still highly demanded nowadays. …”
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