A cost-effective and sensitive TLC-densitometric identification of meloxicam by Parys Wioletta, Pyka-Pająk Alina, Dołowy Małgorzata

“…Comparison of the densitometrically obtained spectra of meloxicam drug and its standard after the use of appropriate visualization agents could be a good and cheap alternative tool for the identification of meloxicam as an active pharmaceutical ingredient.…”
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The Residues and Risk Assessment of Sulfonamides in Animal Products by Xiao-lei Zuo, Han Ai-yun

“…Risk assessment of the consumption of sulfonamide veterinary drugs in livestock and poultry products of Shijiazhuang residents was conducted. …”
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Medication-Related Osteonecrosis of the Jaw: New Insights into Molecular Mechanisms and Cellular Therapeutic Approaches by Thomas Lombard, Virginie Neirinckx, Bernard Rogister, Yves Gilon, Sabine Wislet

“…In recent years, medication-related osteonecrosis of the jaw (MRONJ) became an arising disease due to the important antiresorptive drug prescriptions to treat oncologic and osteoporotic patients, as well as the use of new antiangiogenic drugs such as VEGF antagonist. …”
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Acute Low-Dose Hydralazine-Induced Lupus Pneumonitis by Sarah K. Holman, Donique Parris, Sarah Meyers, Jason Ramirez

“…Genetic testing revealed she was heterozygous for N-acetyltransferase 2 (intermediate acetylator). Drug-induced lupus should be considered in patients with lupus-like symptoms taking medications with a known association. …”
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Noncompliance with Ocular Hypertensive Treatment in Patients with Primary Open Angle Glaucoma among the Arab Population in Israel: A Cross-Sectional Descriptive Study by Muhannad Masoud, Adi Sharabi-Nov, Joseph Pikkel

“…Items included information about age, gender, number of prescribed drugs, and multiple reasons for noncompliance with drug therapy. …”
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A Rare Manifestation of Asymptomatic Ebstein’s Anomaly with Tricuspid Valve Endocarditis by Carmel Moazez, Vicken Zeitjian, Christian Breburda, Ranjini Roy

“…To our knowledge, this represents the fifth reported case of a new diagnosis of Ebstein’s anomaly in the setting of endocarditis and the second case of Ebstein’s anomaly and endocarditis in an intravenous drug abuser.…”
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In silico modelling of organ-on-a-chip devices: an overview by Yue Wang, Lucia Marucci, Lucia Marucci, Lucia Marucci, Martin E. Homer

“…Diverse OOAC devices specific to different organs have been proposed for experimental research and applications such as disease modelling, personalized medicine and drug screening. Previous studies have demonstrated that the mathematical modelling of OOAC can facilitate the optimization of chips’ microenvironments, serving as an essential tool to design and improve microdevices which allow reproducible growth of cell culture, reducing the time and cost of experimental testing. …”
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Deoxygenative photochemical alkylation of secondary amides enables a streamlined synthesis of substituted amines by Antonio Pulcinella, Stefano Bonciolini, Robin Stuhr, Damiano Diprima, Minh Thao Tran, Magnus Johansson, Axel Jacobi von Wangelin, Timothy Noël

“…This approach broadens the synthetic utility of amides, facilitating late-stage modifications of drug-like molecules and the synthesis of saturated N-substituted heterocycles. …”
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The Role of Neurokinin-1 Receptor in the Microenvironment of Inflammation and Cancer by Marisa Rosso, Miguel Muñoz, Michael Berger

“…Antagonists against the NK-1 receptor are safe clinical drugs that are known to have anti-inflammatory, analgesic, anxiolytic, antidepressant, and antiemetic effects. …”
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Bilateral Angle Narrowing and Acute Myopia Induced by Indapamide: A Case Report by Ana Catarina Pedrosa, Joana Rodrigues Araújo, João Paulo Macedo, Sérgio Estrela Silva, António Melo, Fernando Falcão-Reis

“…Therefore, indapamide, as well as other sulfonamide-derived drugs, must always be considered in the differential diagnosis of acute myopia and angle closure.…”
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A Pharmacotherapy and ECT resistant OCD patient’s Cognitive Behavioral Therapy by Tacettin KURU, M. Hakan TÜRKÇAPAR

“…Results: Cognitive Behavioral Therapy is an effective treatment for treatment-resistant patients with drug and ECT.…”
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Optimizing glycerosome formulations via an orthogonal experimental design to enhance transdermal triptolide delivery by Zhu Chunyun, Zhang Yongtai, Wu Tong, He Zehui, Guo Teng, Feng Nianping

“…With entrapment efficiency and drug loading as dependent variables, the glycerosome formulation was optimized using an orthogonal experimental design. …”
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“Le Tétraque se perdait dans un rêve”: Concordance between Flaubert’s Hérodias and Hérodiade by Milliet, Grémont and Massenet by Clair Rowden

“…While Massenet’s opera has always been identified as lacking a dance scene equivalent to the “Dance of the Seven Veils”, this article argues that Hérode’s Act II aria “Vision fugitive” may be read as a drug-induced hallucinatory dance of Salomé before a sexually aroused yet solitary Hérode. …”
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Shionone Relieves Urinary Tract Infections by Removing Bacteria from Bladder Epithelial Cells by Hao Yin, Jiaoli Zhu, Yi Jiang, Yijing Mao, Chenquan Tang, Hui Cao, Yufang Huang, Huijun Zhu, Jianping Luo, Qingjiang Jin, Qinglei Jin, Yi Xue, Xin Wang

“…In clinical practice, urinary tract infections (UTIs) are second only to respiratory infections in terms of infectious diseases. In recent years, drug resistance of Escherichia coli (E. coli) has increased significantly. …”
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Screening of Aqueous Extract of Persea americana Seeds for Alpha-Glucosidase Inhibitors by Tajudeen Afolayan Lawal

“…The subfraction competitively inhibits α-glucosidase (with IC50 = 09.48 ± 0.58 μg/mL), though less potent than the standard drug, acarbose (IC50 = 06.45 ± 0.47 μg/mL). FTIR analysis of the subfraction showed the presence of carbonyl group, hydroxy group, carboxyl group, double bonds, methylene, and methyl groups. …”
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Neurophysiology of Drosophila Models of Parkinson’s Disease by Ryan J. H. West, Rebecca Furmston, Charles A. C. Williams, Christopher J. H. Elliott

“…Finally, the strong neuronal phenotypes permit relevant first in vivo drug testing.…”
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Design, Expression, and Inhibitory Effects of Antagonistic Single-Chain Platelet-Derived Growth Factor on Lung Cancer Cells by Salim Alhafyan

“…This result underscores the potential of the sc-PDGF antagonist as a viable drug candidate for suppressing the proliferation of cancer cells, particularly those in which PDGF plays a critical role in cell growth.…”
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Stroke after Initiating IV Penicillin for Neurosyphilis: A Possible Jarisch-Herxheimer Reaction by Vineet Punia, Appaji Rayi, Adithya Sivaraju

“…Given an increase in incidence of syphilis in recent years, our case underlies the importance of keeping in mind potential catastrophic drug adverse reactions in neurosyphilis patients.…”
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Evaluation of stability and in vitro wound healing potential of melatonin loaded (lipid enriched) chitosan based microspheres by Romić Marieta Duvnjak, Sušac Anja, Lovrić Jasmina, Cetina-Čižmek Biserka, Filipović-Grčić Jelena, Hafner Anita

“…At the end of testing, drug content was determined in all samples. Dressings wound healing potential was assessed by in vitro scratch test using human skin fibroblast cell line. …”
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The Poisson Extension of the Unrelated Question Model: Improving Surveys With Time-Constrained Questions on Sensitive Topics by Benedikt Iberl, Anesa Aljovic, Rolf Ulrich, Fabiola Reiber

“…The UQM is another survey technique which guarantees complete and objective anonymity to participants in order to achieve more valid survey results when asking sensitive questions (e.g., about drug use). The resulting Poisson extension of the UQM (UQMP) is expected to yield valid estimations for how many participants engage in a researched sensitive behavior, and how regularly they do so. …”
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