Shifting the paradigm of type 1 diabetes: a narrative review of disease-modifying therapies by Alexander J. O’Donovan, Seth Gorelik, Seth Gorelik, Laura M. Nally

“…To date, only one medication, teplizumab, has been approved by the Food and Drug Administration (FDA) for the treatment of stage 2 T1D. …”
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Iron oxide nanoparticles coated with bioactive materials: a viable theragnostic strategy to improve osteosarcoma treatment by Amy Sarah Benjamin, Sunita Nayak

“…They can also be easily conjugated to anti-cancer drugs, targeting agents, or genetic vectors that respond to specific stimuli or pH changes. …”
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FusOn-pLM: a fusion oncoprotein-specific language model via adjusted rate masking by Sophia Vincoff, Shrey Goel, Kseniia Kholina, Rishab Pulugurta, Pranay Vure, Pranam Chatterjee

“…FusOn-pLM uniquely predicts drug-resistant mutations, providing insights for therapeutic design that anticipates resistance mechanisms. …”
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A Case Series of Psychological Stress Evaluation as a Risk Factor for Oral Lichen Planus by Irna Sufiawati, Ani Megawati, Muhammad Al Farisyi, I. Nyoman Gede Juwita Putra

“…Suggested predisposing factors for the development of OLP include genetic factors, viral infections, psychological stress, trauma, drug intake, and some systemic diseases. This serial case aimed to evaluate the psychological stress in triggering various types of OLP and its management. …”
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Visualization of microbial biofilms in case of digestive disorders in lambs by E. M. Lenchenko, N. P. Sachivkina, D. A. Blumenkrants, A. Yu. Arsenyuk

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Bioinformatic analysis of ferroptosis related biomarkers and potential therapeutic targets in vitiligo by Linli Liu, Lingli Deng, Li Guan, Yuan Hu, Qianying Li, Chunshui Yu

“…Immune landscape analysis demonstrated that these marker genes influence immune cell composition, particularly showing correlations with CD8 + T cells and regulatory T cells. Furthermore, drug-gene interaction analysis proposed potential therapeutic targets, while ceRNA network analysis uncovered intricate regulatory relationships involving miRNAs and lncRNAs. …”
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An Ecofriendly and Stability-Indicating HPLC Method for Determination of Permethrin Isomers: Application to Pharmaceutical Analysis by Minoo Afshar, Niloufar Salkhordeh, Mehdi Rajabi

“…In forced degradation studies, the drug was subjected to oxidation, hydrolysis, photolysis, and heat. …”
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Myasthenia gravis complicated by pure red cell aplasia with clonal large granular lymphocytosis in the absence of thymoma: a rare case report and literature review by Lijun Du, Yiping Liu, Qiaolin Zhou, Fang Xu

“…Considering the possibility of drug-induced PRCA, azathioprine was replaced with tacrolimus. …”
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Incomplete Resolution of Deep Vein Thromboses during Rivaroxaban Therapy by Jonathan M. Yaghoubian, Jacob Adashek, Bahareh Yaghoubian-Yazi, Menachem Nagar, Nojan Toomari, Richard J. Pietras, Uri M. Ben-Zur

“…The patient’s prescribed drug regimen was changed from rivaroxaban to warfarin, which demonstrated a rapid resolution of the DVTs as determined by ultrasound assessment of our patient’s lower extremity veins. …”
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A RANDOMIZED CONTROLLED TRIAL EXPERIENCE OF TRANSVERSEABDOMINAL PLANE (TAP) BLOCK VERSUS LOCAL ANESTHESIAINFILTRATION AT SURGICAL SITE IN OPEN APPENDICECTOMIES by Rabia Tabassum et al

“…Two groups were classified, Group T (transversus abdominis plane block) group, infiltrating anaesthetic drug in the skin 2” cephalad towards the iliac crest using a “double-pop” technique and Group I (surgical incision) group in which patients received infiltration into the surgical incision. …”
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Role of Mitochondria-Associated Endoplasmic Reticulum Membrane in Inflammation-Mediated Metabolic Diseases by Themis Thoudam, Jae-Han Jeon, Chae-Myeong Ha, In-Kyu Lee

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Nonlinear-Model-Based Analysis Methods for Time-Course Gene Expression Data by Li-Ping Tian, Li-Zhi Liu, Fang-Xiang Wu

“…Such gene expression data has been proved useful in genomic disease diagnosis and drug design. The challenge is how to uncover useful information from such data by proper analysis methods such as significance analysis and clustering analysis. …”
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Simple UV Spectrophotometric Method for the Determination of Fluvastatin Sodium in Bulk and Pharmaceutical Formulations by J. Saminathan, A. S. Sankar, K. Anandakumar, T. Vetrichelvan

“…A simple and cost effective spectrophotometric method is described for the determination of fluvastatin sodium in pure form and in pharmaceutical formulations. When the drug reacts with sodium hydroxide shows absorption maximum at 304 nm and obeys beer's law in the concentration range 5-25 µg mL-1. …”
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A Case of Tuberculous Spondylitis in Child with Undernourish by Erli Meichory Viorika, Finny Fitry Yani, Roni Eka Sahputra

“…The patient was discharged on 6th hospitalization and given anti-tuberculous drug. Keywords:  bump, extrapulmonary, fracture, spondylitis, tuberculosis…”
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Miliary Tuberculosis Induced Acute Liver Failure by Tayfur Toptas, Birkan Ilhan, Huseyin Bilgin, Elif Dincses, Osman Ozdogan, Isik Kaygusuz-Atagunduz, Zekaver Odabasi, Volkan Korten, Tulin Firatli-Tuglular

“…In case of suggestive findings on clinical and radiologic examination, antituberculosis treatment should be initiated immediately. Drug use can be a challenge in patients with ALF. …”
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Post-Autologous (ASCT) Stem Cell Transplant Therapy in Multiple Myeloma by Zeina Al-Mansour, Muthalagu Ramanathan

“…., bortezomib) with an immunomodulatory drug (thalidomide or lenalidomide) have provided the best outcomes. …”
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Effects of the Transcendental Meditation Program on Substance Use among University Students by David A. F. Haaga, Sarina Grosswald, Carolyn Gaylord-King, Maxwell Rainforth, Melissa Tanner, Fred Travis, Sanford Nidich, Robert H. Schneider

“…For smoking and illicit drug use, there were no significant differences between conditions. …”
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Site-Specific Immunosuppression in Vascularized Composite Allotransplantation: Prospects and Potential by Jonas T. Schnider, Matthias Weinstock, Jan A. Plock, Mario G. Solari, Raman Venkataramanan, Xin Xiao Zheng, Vijay S. Gorantla

“…Logically, antirejection drugs, biologics, or other agents delivered locally to the VCA may reduce the need for systemic immunosuppression with its adverse effects. …”
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Liver Injury with Features Mimicking Autoimmune Hepatitis following the Use of Black Cohosh by Grace Guzman, Eric R. Kallwitz, Christina Wojewoda, Rohini Chennuri, Jamie Berkes, Thomas J. Layden, Scott J. Cotler

“…Their liver biopsies showed a component of centrilobular necrosis consistent with severe drug-induced liver injury. In addition, the biopsies showed characteristics of autoimmune-like liver injury with an interface hepatitis dominated by plasma cells. …”
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Synthesis and Antifungal Activity of β-Hydroxysulfides of 1,3-Dioxepane Series by Roman S. Pavelyev, Rusalia M. Vafina, Konstantin V. Balakin, Oleg I. Gnezdilov, Aleksey B. Dobrynin, Olga A. Lodochnikova, Rashid Z. Musin, Galina A. Chmutova, Svetlana A. Lisovskaya, Liliya E. Nikitina

“…Study of antifungal activity of the obtained compounds showed that some enantiomerically pure 6-arylthio-1,3-dioxepan-5-ols represent promising antifungal drug candidates.…”
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