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5001
Iron Chelators in Treatment of Iron Overload
Published 2022-01-01“…In clinical use, deferoxamine, deferiprone, and deferasirox are the three United States Food and Drug Administration-approved iron chelators. Each of these iron chelators is well known for the treatment of iron overload in various clinical conditions. …”
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5002
Novel Antiplatelet Agent Use for Acute Coronary Syndrome in the Emergency Department: A Review
Published 2013-01-01“…Further clinical trials involving head-to-head trials or comparisons of drug-based strategies are required to show superiority in reducing cardiac endpoints with regard to ED initiation of treatment.…”
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5003
Hot shape transformation: the role of PSar dehydration in stomatocyte morphogenesis
Published 2025-01-01“…These novel structures exhibit asymmetry and possess the capability to encapsulate smaller structures, thereby broadening their potential applications in drug delivery and nanotechnology. Our findings shed light on the unique capabilities of polysarcosine-based polymers, paving the way for further exploration and harnessing of their distinctive properties in biomedical research.…”
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5004
Ultraviolet Spectrophotometric Method for Determination of Glipizide in Presence of Liposomal/Proliposomal Turbidity
Published 2013-01-01“…Conclusively, our method was successfully applied for the determination of glipizide in clear as well as turbid solutions, and it was found that the drug analyte in both types of solutions can be detected from the same calibration curve accurately and precisely and glipizide entrapped in the liposomes or in proliposomal matrix was not detected.…”
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5005
Effects of Microtubule Stabilization by Epothilone B Depend on the Type and Age of Neurons
Published 2016-01-01“…Here, we have examined and compared the effects of a brain-penetrant MSA, epothilone B, on cortical and sensory neurons in culture and show that epothilone B exhibits both beneficial and detrimental effects, depending on not only the concentration of drug but also the type and age of a neuron, as seen in clinical settings. …”
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5006
Canadian Standards Association Standard CAN/CSA/Z264.1-02:2002: A New Voluntary Standard for Spacers and Holding Chambers Used with Pressurized Metered-Dose Inhalers
Published 2004-01-01“…Whereas monographs in the pharmaceutical compendia and guidance documents published by regulatory bodies provide information that is largely about the drug product and inhaler, this is the only standard whose focus is primarily on these add-on devices. …”
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5007
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5008
Significance of Algal Polymer in Designing Amphotericin B Nanoparticles
Published 2014-01-01“…In vivo and in vitro antifungal activity demonstrated the high antifungal potential of optimized formulation when compared with standard drug and marketed formulations. Throughout the study TPP addition did not cause any significant changes. …”
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5009
Pathogenic and therapeutic roles of extracellular vesicles in sepsis
Published 2025-02-01“…The engineering EVs-mediated drug delivery and release strategies offer broad prospects for the effective treatment of sepsis. …”
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5010
Tissue engineering and biosensing applications of carbon-based nanomaterials
Published 2025-06-01“…This study highlights the unique mechanical, electrical, and biocompatible properties of CNMs that make them indispensable for applications such as drug delivery, biosensing, tissue engineering, and medical implants. …”
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5011
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5012
Tyrosinase Inhibitory Effect and Antioxidative Activities of Fermented and Ethanol Extracts of Rhodiola rosea and Lonicera japonica
Published 2013-01-01“…The results indicated that fermentation of Rhodiola rosea and Lonicera japonica can be considered as an effective biochemical process for application in food, drug, and cosmetics.…”
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5013
Insulin Independence in Newly Diagnosed Type 1 Diabetes Patient following Fenofibrate Treatment
Published 2020-01-01“…Fenofibrate is a widely used drug for reducing triglyceride and cholesterol levels. …”
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5014
Synthetic Cannabis Overdose and Withdrawal in a Young Adult: A Case Report, Commentary on Regulation, and Review of the Literature
Published 2016-01-01“…It is believed that the popularity of SM has increased, due to its easy accessibility in the US and lack of detection in typical urine drug screens for THC. Case Report. One case presented is of a young adult patient, with histories of recurrent synthetic cannabis and recreational cannabis use, who had developed drastic physiological and psychiatric symptoms, including the development of acute-onset psychosis. …”
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5015
Real-world studies of crizotinib in patients with ROS1-positive non-small-cell lung cancer: experience from China
Published 2024-12-01“…As one of the leading countries of real-world research on crizotinib, China has contributed significantly to data on standardization of the therapeutic use of crizotinib, including its clinical treatment patterns, the timing and duration of treatment and drug resistance monitoring and management.…”
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5016
Simultaneous Determination of Lamotrigine, Oxcarbazepine, Lacosamide, and Topiramate in Rat Plasma by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry
Published 2022-01-01“…This study established an ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method to study the pharmacokinetics of four antiepileptic drugs, lamotrigine, oxcarbazepine, lacosamide, and topiramate, in rats after oral administration. …”
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5017
Structural Characters and Pharmacological Activity of Protopanaxadiol-Type Saponins and Protopanaxatriol-Type Saponins from Ginseng
Published 2024-01-01“…Ginseng has a long history of drug application in China, which can treat various diseases and achieve significant efficacy. …”
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5018
Complete genome of mangrove-derived anti-MRSA streptomycete, Streptomyces pluripotens MUSC 135T
Published 2018-10-01“…The availability of S. pluripotens MUSC 135T genome sequence has opened new window for drug discovery, particularly for effective drugs against harmful pathogens such as MRSA and certainly deserves further detailed study. …”
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5019
Family Practitioners and Sexually Transmitted Diseases
Published 1991-01-01“…Assessment of risks for hepatitis B virus infection should include lifestyle indices such as sexual preference, sexual expression, number of partners and alcohol/drug consumption. Prostitutes, street youth and sexually abused individuals should be considered at high risk for hepatitis B virus infection. …”
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5020
Design, Synthesis and Potential Anti-Proliferative Activity of Some Novel 4-Aminoquinoline Derivatives
Published 2014-09-01“…Seventeen of the novel compounds showed higher activity than the reference drug doxorubicin. The corresponding 7-(trifluoromethyl)-N-(3,4,5-trimethoxyphenyl)quinolin-4- amine 1, N-(7-(trifluoromethyl)quinolin-4-yl)quinolin- 3- amine (10), 2-methyl-N-(7-trifluorome-thyl)quinolin-4-yl) quinolin-3-amine (11) and N-(4-(4-aminophenylsulfonyl) phenyl)-7-chloroquinolin-4-amine (13) were almost twice to thrice as potent as doxorubicin. …”
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