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4841
Green synthesis, characterization, and antibacterial activity investigation of zinc oxide nanoparticles using Rumex Nervosus Vahl Leaf extract
Published 2025-01-01“…Therefore, the eco- friendly synthesis of zinc oxide nanoparticles using Rumex Nervosus Vahl Leaf extract is a promising approach for developing new drug products with efficient antibacterial properties, and it could be evaluated as an opportunity for in vivo biomedical applications with positive environmental impacts.…”
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4842
Corticostriatal contributions to dysregulated motivated behaviors in stress, depression, and substance use disorders
Published 2025-02-01“…Stress-induced depression and substance use disorders (SUDs) both share this common underlying pathology, manifested as deficits in perceived reward in depression, and increased attribution of positive valence to drug-predictive stimuli and dysfunctional cognition in SUDs. …”
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4843
Acute Toxicity of Dental Gel Based on Origanum vulgare in Mice
Published 2023-01-01“…According to the results of a morphometric study conducted 15 days after the administration of the drug, no deviations were found. The histological evaluation of organs showed little change in the cardiac architecture in animals treated with ACDG3 at doses of 1000 mg/kg and 2000 mg/kg. …”
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4844
Molecular Generation and Optimization of Molecular Properties Using a Transformer Model
Published 2024-03-01“…Generating novel molecules to satisfy specific properties is a challenging task in modern drug discovery, which requires the optimization of a specific objective based on satisfying chemical rules. …”
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4845
Giant Pheochromocytoma Diagnosis Confounded by Amphetamine Use
Published 2023-01-01“…At times, presence of sympathetic stimulant drugs can further complicate the clinical picture. …”
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4846
Diabetes and Stroke Prevention: A Review
Published 2012-01-01“…Hypertension should be treated with a target of 140/80 mmHg, as a maximum. The drug of choice would be an ACE inhibitor, although the priority is blood pressure reduction regardless of the medication chosen. …”
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4847
Kerala’s fight against Nipah Virus: Surveillance and safety measures intensify
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4848
Concentration and health risk assessment of melamine in commercial citrus juices
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4849
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4850
Effects of polyunsaturated fatty acids on mitigation of the side effects of isotretionin treatment for patients with acne vulgaris: a narrative review
Published 2024-12-01“…Despite its high efficacy, it causes adverse effects including dryness of the mucous membranes, lips and skin, cheilitis, erythema, headache, muscle and joint pain. Long-term use of the drug can also cause liver dysfunction, lipid metabolism and also cause an increase in uric acid levels. …”
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4851
Nonnutritive, Low Caloric Substitutes for Food Sugars: Clinical Implications for Addressing the Incidence of Dental Caries and Overweight/Obesity
Published 2012-01-01“…Although there are only five artificial sweeteners that have been approved as food additives by the Food and Drug Administration (FDA), there are additional five non-/low caloric sweeteners that have FDA GRAS (Generally Recognized as Safe) designation. …”
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4852
siMacro: A Fast and Easy Data Processing Tool for Cell-Based Genomewide siRNA Screens
Published 2013-03-01“…Growing numbers of studies employ cell line-based systematic short interfering RNA (siRNA) screens to study gene functions and to identify drug targets. As multiple sources of variations that are unique to siRNA screens exist, there is a growing demand for a computational tool that generates normalized values and standardized scores. …”
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4853
Advancements in Nanomedicine for the Diagnosis and Treatment of Kidney Stones
Published 2025-02-01“…By mitigating oxidative stress-induced cellular damage, nanomaterials can inhibit the formation of kidney stones and enhance the efficacy of drug delivery as effective carriers. Additionally, by modifying the physical and chemical properties of bacteria, nanomaterials can effectively eliminate bacterial presence, thereby preventing severe complications. …”
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4854
Mesalazine use tactics in the ulcerative colitis patients
Published 2013-03-01“…To specify indications for the administration of the 5-aminosalicylic acid (5-АSA) in the patients with ulcerative colitis (UC) and to discuss the possibility of correlation between the body mass index, the disease activity and reasonability for the prescription of the mesalazine (Pentasa) as a monotherapy.Key points. 5-АSA is the first line drug for the UC patients. The efficacy has been demonstrated in a huge number of studies, the indications for the administration have been determined and are dependent on the disease activity index. 5-АSA are used in moderate rate of the inflammatory activity. …”
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4855
Application and Validation of Simple Isocratic HPLC-UV-DAD Method with Dual Wavelength Detection for Ivabradine Determination and Its Application in the Study of Stress Degradation
Published 2017-01-01“…Ivabradine is a modern drug that selectively lowers the heart rate, improves cardiac energy balance, and reduces heart’s demands for oxygen and energy. …”
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4856
Collaboration between HPMC and NaCMC in order to Reach the Polymer Critical Point in Theophylline Hydrophilic Matrices
Published 2012-01-01“…In a previous work carried out with the same polymers but a much more soluble drug (KCl), it was demonstrated the existence of a partial collaboration between the polymers in order to establish the gel layer. …”
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4857
Bile Reflux Gastritis: Insights into Pathogenesis, Relevant Factors, Carcinomatous Risk, Diagnosis, and Management
Published 2022-01-01“…From lifestyle modification to drug therapy to surgery, all of them with the view of realizing symptomatic relief are employed for patients with BRG. …”
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4858
Unusual Complication of Multidrug Resistant Tuberculosis
Published 2017-01-01“…Capreomycin is a second-line drug often used for multidrug-resistant tuberculosis which can result in nephrotoxic effects similar to other aminoglycosides. …”
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4859
Adverse Immunologically Mediated Oral Mucosal Reactions to Systemic Medication: Lichenoid Tissue Reaction/Interface Dermatitis-Stomatitis, Autoimmune Vesiculobullous Disease, and I...
Published 2018-01-01“…Drug-induced hypersensitivity immune reactions are exaggerated immunoinflammatory responses to allergenic components of the medications that occur in genetically susceptible subjects. …”
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4860