Relationship between programmed cell death and targeted therapy for thyroid cancer in patients with a poor prognosis: an update by Yuejia Zhao, Simeng Zhao, Zhe Fan, Yongfu Zhao, Guangzhi Wang

“…We also provide an outlook on future treatments for drug-resistant thyroid cancer, poorly differentiated thyroid cancer, and iodine-refractory thyroid cancer, aiming to accurately identify targets and offer effective targeted therapeutic strategies.…”
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A Survey of Mycotoxin Contamination in Fermented Condiments and the Biological Methods for Its Reduction by WANG Lihui, FU Jinhui, LI Chaowei, ZHANG Li, XIA Xiaolong, LI Sitong, ZHANG Mengmei, CHEN Yinzhu, LIU Shuliang, HU Kaidi, ZHAO Ning, LI Qin, LI Jianlong

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Characterization and taste masking evaluation of microparticles with cetirizine dihydrochloride and methacrylate-based copolymer obtained by spray drying by Amelian Aleksandra, Szekalska Marta, Ciosek Patrycja, Basa Anna, Winnicka Katarzyna

“…Obtained data have shown that microparticles with a drug/polymer ratio (0.5:1) are promising CET carriers with efficient taste masking potential and might be further used in designing orodispersible dosage forms with CET.…”
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Analysis of HIV therapy in the liver using optimal control and pharmacokinetics by Hasifa Nampala, Matylda Jabłońska-Sabuka, Martin Singull

“…For second-line regimen, the period of drug administration of PIs largely depends on the weight constants. …”
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Inhaling Difluoroethane Computer Cleaner Resulting in Acute Kidney Injury and Chronic Kidney Disease by Kristen Calhoun, Laura Wattenbarger, Ethan Burns, Courtney Hatcher, Amol Patel, Manjulatha Badam, Abdul-Jabbar Khan

“…Difluoroethane is the active ingredient in various computer cleaners and is increasingly abused by teenagers due to its ease of access, quick onset of euphoric effects, and lack of detectability on current urine drug screens. The substance has detrimental effects on various organ systems; however, its effects on the kidneys remain largely unreported. …”
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Electron Paramagnetic Resonance Study of Thermally Treated Bismuth Subgallate by Paweł Ramos, Barbara Pilawa

“…Complex of bismuth, an anti-inflammatory drug, was studied by EPR spectroscopy. The aim of this study was to determine concentrations and properties of free radicals formed during thermal sterilization of bismuth subgallate according to pharmacopoeia norms to optimize its sterilization process. …”
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Suicide in New Zealand by Said Shahtahmasebi

“…A straightforward contextual analysis of this information suggests that (i) only five cases had contact with mental health services, in two of the cases this was due to a previous suicide attempt and in the other three it was due to drug and alcohol dependency; (ii) mental illness as the cause of suicide is fixed in the public mindset, (iii) this in turn makes psychological autopsy type studies that seek information from families and friends questionable; (iv) proportionally more females attempt, but more men tend to complete suicide; and (v) not only is the mental health-suicide relationship tenuous, but suicide also appears to be a process outcome. …”
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Rheological Characterization of Isabgol Husk, Gum Katira Hydrocolloids, and Their Blends by Vipin Kumar Sharma, Bhaskar Mazumder, Vinod Nautiyal

“…Moreover, the study indicated the applicability of these blends in the development of drug delivery systems and in industries, for example, ice-cream, paste, nutraceutical, and so forth.…”
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Asthma in Sickle Cell Disease: Implications for Treatment by Kathryn Blake, John Lima

“…Prospective controlled trials of drug treatment for asthma in patients who have both sickle cell disease and asthma are urgently needed.…”
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A Validated HPLC-DAD Method for Simultaneous Determination of Etodolac and Pantoprazole in Rat Plasma by Ali S. Abdelhameed, Samar A. Afifi

“…A simple, sensitive, and accurate HPLC-DAD method has been developed and validated for the simultaneous determination of pantoprazole and etodolac in rat plasma as a tool for therapeutic drug monitoring. Optimal chromatographic separation of the analytes was achieved on a Waters Symmetry C18 column using a mobile phase that consisted of phosphate buffer pH~4.0 as eluent A and acetonitrile as eluent B in a ratio of A : B, 55 : 45 v/v for 6 min, pumped isocratically at a flow rate of 0.8 mL min−1. …”
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Public health care system, a quasi-experimental study: Acceptance and attitude to implicate clinical services by Gillani Syed Wasif, Abdul Mohi Iqbal Mohammad

“…The predictive model suggested a strong positive effect on patient interaction, medical information tasks, clinical decisions on drug-related problems (DRPs), and communication with healthcare professionals (R2 = 0.41, F = 1.51, p < 0.001).…”
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Tamarind Seed Xyloglucans Promote Proliferation and Migration of Human Skin Cells through Internalization via Stimulation of Proproliferative Signal Transduction Pathways by W. Nie, A. M. Deters

“…Xyloglucans (XGs) of Tamarindus indica L. Fabaceae are used as drug vehicles or as ingredients of cosmetics. Two xyloglucans were extracted from T. indica seed with cold water (TSw) and copper complex precipitation (TSc). …”
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Advancing pancreatic cancer research and therapeutics: the transformative role of organoid technology by Jihao Xu, Minh Duc Pham, Vincenzo Corbo, Mariano Ponz-Sarvise, Tobiloba Oni, Daniel Öhlund, Chang-Il Hwang

“…We explore the applications of pancreatic organoids in dissecting the tumor microenvironment (TME); elucidating cancer progression, metastasis, and drug resistance mechanisms; and personalizing therapeutic strategies. …”
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Gastrointestinal Stromal Tumours: Etiology, Pathology and Clinical Management by Martin E Blackstein, Pierre Dubé, Jonathan A Fletcher, Oliver R Keller, Margaret Knowling, Richard Létourneau, Donald Morris, Robert Riddell, Stewart Rorke, Carol J Swallow, Canadian Advisory Committee on GIST

“…In the present review, results with the prototype drug of this class, imatinib (Gleevec, Glivec [formerly STI571]; Novartis, Switzerland), in metastatic gastrointestinal stromal tumours are presented. …”
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Developing a Versatile Arsenal: Novel Antimicrobials as Offensive Tools Against Pathogenic Bacteria by Junze Ma, Zheng Lu

“…The pervasive and often indiscriminate use of antibiotics has accelerated the emergence of drug-resistant bacterial strains, thus presenting an acute threat to global public health. …”
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AXL inhibitors selected by molecular docking: Option for reducing SARS-CoV-2 entry into cells by Galindo-Hernández Octavio, Vique-Sánchez José Luis

“…This study proposes ten compounds (1–10), selected by mole-cu lar docking and using a library of nearly 500,000 compounds, to develop a new drug that will decrease the interaction of AXL with the S protein of SARS-CoV-2. …”
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A Case of Recurrent Cryptococcal Meningoencephalitis in an Immunocompetent Female by Negin Niknam, Negar Niknam, Kola Dushaj, Erfidia Restrepo

“…We describe a 39-year-old immunocompetent female that presented with neurologic deficits and increased intracranial pressure (ICP) due to cryptococcal meningoencephalitis that had a complicated course with drug induced hepatitis and persistently increased ICP that ultimately required shunt placement and presented again with relapse of cryptococcal meningoencephalitis after completion of antifungal treatment. …”
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Role of the Synthetic B1 Vitamin Sulbutiamine on Health by Bernardo Starling-Soares, Pedro Carrera-Bastos, Lucien Bettendorff

“…Sulbutiamine is a thiamine derivative developed in Japan in the mid-60’s as a beriberi treatment drug. Since then, different potential applications have been described. …”
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Characterization of Novel Edible Films and Coatings for Food Preservation Based on Gum Cordia by Hadi Hashemi Gahruie, Reza Safdarianghomsheh, Parisa Zamanifar, Shahriyar Salehi, Mehrdad Niakousari, Seyed Mohammad Hashem Hosseini

“…The mucilage possesses outstanding technofunctional properties as an emulsifier, thickening agent, and binding and stabilizing component in food and drug industries. The backbone of gum Cordia is composed of (1-2)-linked L-arabinofuranosyl and (1–6)-linked D-glucopyranosyl residues. …”
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The Ameliorative Role of Probiotics in 5-fluorouracil Induced Intestinal Mucositis by Alexandra Arcilla Xin Hui Sim, Jia Ying Cheam, Jodi Woan-Fei Law, Vengadesh Letchumanan, Yatinesh Kumari, Satoshi Ogawa, Sunny Hei Wong, Kok-Gan Chan, Loh Teng-Hern Tan

“…Although early detection improves the survival rate to around 90%, late detection would mean the need to use chemotherapy or radiotherapy, especially if surgery is not feasible. 5-fluorouracil (5-FU) is one of the common anti-cancer drugs used in treating CRC. It is the drug that has the greatest efficacy on CRC. …”
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