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4621
Spectrophotometric and Conductometric Determination of Clomiphene Citrate and Nefazodone HCl
Published 2008-01-01“…The molar combining ratio reveal that (1:1) (drug : reagent) ion associates were formed.…”
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4622
Brugada Pattern Electrocardiogram Unmasked with Cocaine Ingestion
Published 2013-01-01“…Cocaine is considered a leading cause of drug-related deaths. This is usually sudden, unwitnessed, and without prodromal features. …”
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4623
Screening of potential GCMS derived antimigraine compound from the leaves of Abrus precatorius Linn to target “calcitonin gene related peptide” receptor using in silico analysis...
Published 2019-03-01“…Many strategies were employed to design antimigraine drug using various CGRP antagonist/ligands but most of them have failed due to their inability to reach the target “CGRP receptor” as they get metabolized before conferring their pharmacological action and exhibit toxic effect to the liver. …”
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4624
Study on the regulatory mechanisms of mitochondrial biosynthesis by polyoxometalates
Published 2025-03-01“…The antioxidant and antitumor properties of POMs are promising for future therapeutic drugs. By examining oxidative stress and its impact on various biomolecules, POMs have been recognized as a drug therapy mechanism closely linked to mitochondria. …”
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4625
Preclinical advance in nanoliposome-mediated photothermal therapy in liver cancer
Published 2025-01-01“…Although traditional treatment methods such as surgery, radiotherapy, and chemotherapy have increased the survival rate of patients, their efficacy remains unsatisfactory owing to the nonspecific distribution of drugs, high toxicity, and drug resistance of tumor tissues. …”
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4626
A review of the pathogenesis of mitochondria in breast cancer and progress of targeting mitochondria for breast cancer treatment
Published 2025-01-01“…However, the heterogeneity, drug resistance, and poor prognosis of breast cancer highlight an urgent need for further exploration of its underlying mechanisms. …”
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4627
Alginate Nanoparticles Containing Cuminum cyminum and Zataria multiflora Essential Oils with Promising Anticancer and Antibacterial Effects
Published 2024-01-01“…This study investigated alginate nanoparticles loaded with essential oils (EOs) from Cuminum cyminum and Zataria multiflora as potential drug delivery systems. The nanoparticles were comprehensively characterized using techniques such as gas chromatography-mass spectrometry (GC-MS), dynamic light scattering (DLS), zetasizer, attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), and ultraviolet-visible spectroscopy (UV-Vis). …”
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4628
EpigenomeViewer: A Shiny Web Application for Visualizing Methylation Patterns Across Biological Samples
Published 2025-02-01“…EpigenomeViewer is particularly useful in the study of drug resistance and early stage cancer biomarkers, where understanding methylation differences between tumour and normal samples is vital. …”
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4629
Metabonomics Research Progress on Liver Diseases
Published 2017-01-01“…Many other liver diseases, such as drug-induced liver injury (DILI), alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD), and autoimmune liver diseases, still do not have definite diagnostic markers; the diagnosis consists of history, medical imaging, and the relevant score. …”
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4630
Reflections on the US FDA's Warning on Direct-to-Consumer Genetic Testing
Published 2014-12-01“…In November 2013, the US Food and Drug Administration (FDA) sent a warning letter to 23andMe, Inc. and ordered the company to discontinue marketing of the 23andMe Personal Genome Service (PGS) until it receives FDA marketing authorization for the device. …”
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4631
The hydrochemistry of Angwan Mallam and environs (PART OF KEFFI SHEET 208 NE)
Published 2013-05-01“…The findings will be a benefit to Environmental Impact Assessment of Agwa mallam as the water in the area meets the National Agency for Food, Drug Administration and Control, Draft for National Standard for Drinking water, and World Health Organization guideline. …”
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4632
مروری بر خواص و کاربردهای رنگ طبیعی قرمزدانه در صنایع مختلف
Published 2016-02-01“…این رنگزا قدمتی طولانی دارد و علاوه بر استفاده از آن در صنعت رنگرزی الیاف طبیعی مورد استفاده در فرش دستباف ایرانی، در صنایع دارویی، غذایی، آرایشی و بهداشتی نیز مصارف گوناگونی دارد و باعث اهمیت قرمزدانه به عنوان یک رنگزای طبیعی FDC (Food, Drug, Cosmetic) گردیده است. همچنین از آن به عنوان معرف برای شناسایی فلزات استفاده میشود و این رنگزا از طریق کمپلکس با فلزات مختلف خاصیت فلورسانس و لومینسانس از خود نشان میدهد. …”
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4633
Aripirazole and Cognitive Behavioral Therapy in Adolescents with Obsessive-Compulsive Disorder: Case Study
Published 2016-04-01“…Repetitive behaviors or mental acts that individual feels driven to perform in response to an obsession or acording to rules that must be applied rigidly because of preventing or reducing anxiety. Several drug and pschosocial treatments have been suggested for OCD that including both cognitive and behavioral aspects. …”
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4634
Profile of STING agonist and inhibitor research: a bibliometric analysis
Published 2025-02-01“…Future research is expected to focus on drug development and clinical applications. This comprehensive bibliometric analysis provides clinical insights and a guide for further investigation to STING agonist/inhibitor.…”
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4635
Effect in vitro of the Phenobarbital on the Activity of the Enzyme Adenosine Triphosphatase (ATPase) of Sodium and Potassium Dependent in Human Placenta.
Published 2007-12-01“…<p><strong>Background: </strong>Most of the drugs can pass to the fetus through the placenta, conditioning alterations of the development and fetal growth. …”
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4636
Missed rifampicin and isoniazid resistance by commercial molecular assays
Published 2024-07-01“… Drug-resistant tuberculosis (TB) has poor outcomes unless resistance is detected early, ideally by commercially available molecular tests. …”
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4637
Viloxazine for the Treatment of Attention Deficit Hyperactivity Disorder
Published 2022-09-01“…However, nonstimulant drugs such as viloxazine, atomoxetine, guanfacine, and clonidine are becoming more popular due to minimal adverse effects when compared to stimulants…”
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4638
Research Progress on the GIP/GLP-1 Receptor Coagonist Tirzepatide, a Rising Star in Type 2 Diabetes
Published 2023-01-01“…Ongoing trials (NCT04166773) and evidence suggest that it appears to be a promising drug in the areas of NAFLD, renal, and neuroprotection. …”
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4639
Mechanism of action of 5-arninosalicylic acid
Published 1992-01-01“…5-Aminosalicylic Acid (5-ASA) has been used for over 50 years in the treatment of inflammatory bowel disease in the pro-drug form sulphasalazine (SASP). SASP is also used to treat rheumatoid arthritis. …”
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4640
Subcutaneous Extended-Release Buprenorphine Use in Pregnancy
Published 2020-01-01“…Both declined further injections, as well as oral buprenorphine. Serial urine drug screens remained positive for buprenorphine through delivery in both cases. …”
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