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4561
Construction of Nanomaterials and the Role of Rutin in the Treatment of Cerebral Hemorrhage
Published 2022-01-01“…Then, the nanocomposite of rutin electrochemical detection is analyzed, and finally rutin and analog brain drug dynamics is discussed. The experimental results showed that the RSD of samples at room temperature, freeze-thaw cycles, and long-term stability of the mice were less than 5.0%, and the stability of mouse brain tissue homogenate samples completely meets the requirements of troxerutin, rutin, and troxerutin aglycone.…”
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4562
Effect of Opioid on Adult Hippocampal Neurogenesis
Published 2016-01-01“…Many studies focus on the factors that regulate proliferation and fate determination of adult neural stem/progenitor cells, including addictive drugs such as opioid. Here, we review the most recent works on opiate drugs’ effect on different developmental stages of adult hippocampal neurogenesis, as well as the possible underlying mechanisms. …”
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4563
Gastroesophageal reflux disease, resistant to proton pump inhibitors
Published 2011-06-01“…Pharmacological therapy of GERD is focused on change of refluxate properties besides decreasing of its volume and aggressive properties by such classes of drugs, as antacids, alginates and hydrochloric acid secretion inhibitors. …”
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4564
Pulmonary vascular malformations in genetic epileptic encephalopathy: A rare, fatal case report
Published 2025-01-01“…., affected by a KCNT1-related drug-resistant epileptic encephalopathy, who presented fatal complications with massive hemoptysis due to SPCAs. …”
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4565
Investigation of the effıciency of pomegranate (punica granatum l.) peel extract on herpes simplex virus-1
Published 2022-06-01“…Extract against Herpes viruses and other viruses will contribute to antiviral drug trials in the future.…”
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4566
Antivascular Endothelial Growth Factor Agents for Neovascular Age-Related Macular Degeneration
Published 2012-01-01“…Two anti-VEGF agents have been approved by the US Food and Drug Administration (FDA) for the treatment of neovascular AMD. …”
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4567
Chronic Eosinophilic Leukemia—Not Otherwise Specified (NOS) in the Background of a Large Cell Lymphoma
Published 2013-01-01“…Most eosinophilia tends to be due to secondary causes such as infections, hypersensitivity conditions, drug reactions, and connective tissue disorders. …”
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4568
A Case of Rituximab Use as an Induction and Maintenance of Remission in ANCA-Associated Vasculitis
Published 2016-01-01“…She responded initially to rituximab as induction therapy but failed to respond in the maintenance course of the drug. Rituximab was stopped and mycophenolate mofetil was administered. …”
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4569
Prevalence of Helminthic Infections in the Gastrointestinal Tract of Cattle in Mazandaran Province (Northern Iran)
Published 2022-01-01“…Despite the fact that farmers use antiparasitic drugs, helminthic infections in cattle are still high. …”
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4570
Acute Coronary Syndrome after 17 Years of Bare Metal Stent Implantation: “Very” Very Late Stent Thrombosis
Published 2020-01-01“…VLST is a rare entity with drug-eluting stents and even rarer with bare metal stents. …”
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4571
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4572
Current Pharmacological Advances in the Treatment of Cardiac Arrest
Published 2012-01-01“…There are three groups of drugs relevant to the management of cardiac arrest: vasopressors, antiarrhythmics, and other drugs such as sodium bicarbonate, calcium, magnesium, atropine, fibrinolytic drugs, and corticosteroids.…”
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4573
Comprehensive Analysis of Masking Techniques in Molecular Graph Representation Learning
Published 2025-01-01“…Molecule representation learning is a primary area of focus in drug discovery and molecular property prediction. …”
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4574
Peripheral Mechanisms of Symptom Generation in Irritable Bowel Syndrome
Published 2001-01-01“…The gut and the autonomic nervous system are principal areas of research in identifying mechanisms underlying symptom generation and in the identification of new targets for drug development. While motility changes occur in IBS, they are neither specific nor predictable, and this is one reason why drugs aimed at influencing motility patterns have enjoyed limited success to date. …”
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4575
Levamisole-Contaminated Cocaine: An Emergent Cause of Vasculitis and Skin Necrosis
Published 2014-01-01“…Levamisole was used as an antihelminth drug and later was rescinded from use in humans due to adverse effects. …”
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4576
Invasive Microascus trigonosporus Species Complex Pulmonary Infection in a Lung Transplant Recipient
Published 2015-01-01“…Nebulized liposomal amphotericin B was used in addition to systemic therapy in order to optimize antifungal drug exposure; this regimen appeared to reduce the patient’s fungal burden. …”
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4577
Methamphetamine Use: A Narrative Review of Adverse Effects and Related Toxicities
Published 2022-09-01“…Methamphetamine has been labeled "America's most dangerous drug" and has received significant public health attention. …”
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4578
Biological Properties and Clinical Significance of Lipoprotein-Associated Phospholipase A2 in Ischemic Stroke
Published 2022-01-01“…In the last two decades, a number of studies have revealed that both the concentration and the activity of Lp-PLA2 are independent biomarkers of ischemic stroke. The US Food and Drug Administration (FDA) has approved two tests to determine Lp-PLA2 mass and activity for predicting stroke. …”
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4579
Towards Curative Therapy in Burkitt Lymphoma: The Role of Early African Studies in Demonstrating the Value of Combination Therapy and CNS Prophylaxis
Published 2012-01-01“…Complete response was observed with many drugs used as single agents, but Ziegler and colleagues showed that patients resistant to one drug could achieve cure and potentially long-term survival with other drugs. …”
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4580
Melittin: A Natural Component of Honeybee Venom as a Potential Anti-Cancer Therapy
Published 2023-12-01“…These include lack of selectivity, side effects and drug resistance. The hallmarks of cancer are a fundamental concept which aids the development of new means to treat human cancers through the understanding of the acquisition of these hallmarks from cells. …”
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