Personalized solutions for ENT implants: The role of 3D/4D printing by Jigar Vyas, Nensi Raytthatha, Puja Vyas, Jitendra Patel

“…The manuscript explores the potential of 3D printing to revolutionize pharmaceutical and clinical practice, enabling the development of personalized drug formulations, patient-centric implants, and anatomical models. …”
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PI3K/AKT/PTEN Signaling as a Molecular Target in Leukemia Angiogenesis by Naoko Okumura, Hitomi Yoshida, Yasuko Kitagishi, Mutsumi Murakami, Yuri Nishimura, Satoru Matsuda

“…However, it has become an attractive target for drug therapy against leukemia, because angiogenesis is a key process in malignant cell growth. …”
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Mycoplasma pneumoniae-Induced-Stevens Johnson Syndrome: Rare Occurrence in an Adult Patient by Samad Rasul, Faria Farhat, Yared Endailalu, Fatima Tabassum Khan, Vishal Poddar

“…He clinically responded after treatment with antibiotics and IVIG. SJS is usually a drug-induced condition; however, M. pneumoniae is the commonest infectious cause and should be considered in the differential diagnosis.…”
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Therapy of Inflammatory Bowel Disease using New 5-ASA Compounds: An Introduction by Ulrich Klotz

“…Strong evidence has been accumulating that mesalazine (5- aminosalicylic acid, 5-ASA) represents the therapeutic moiety of the standard drug sulphasalazine. Since the active metabolite avoids the toxic potential of sulphapyridine, this perception has initiated new therapeutic approaches, for example, two 5-ASA molecules have been coupled to form another prodrug (olsalazine) which again depends on a proper cleavage of the azobond by bacteria in the colon A more direct way has been applied successfully by administering 5-ASA itself in special galenic formulation (suppositories, enemas, controlled release preparations) to provide enough active material at the proposed sites of action in the terminal ileum and/or colon. …”
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Dynamic properties and diverse applications of deep eutectic solvents by Sanjeeta, Ajay Singh, Jyoti Kavirajwar

“…Their vast uses in different domains, like drug delivery, synthesis, extraction of material, and electrochemistry aspects are discussed in detail. …”
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Study of the β-Cyclodextrin Imipramine Hydrochloride Inclusion Complex and Determination of its Stability Constant (K) by UV-Visible Spectroscopy by Alamdar Ashnagar, Nahid Gharib Naseri, Bita Khanaki

“…In this research, the interactions of imipramine hydrochloride drug with β- cyclodextrin and the stability constant (K) of the inclusion complex formed between them were investigated by using UV-visible spectroscopy. …”
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Dynamical Models of Tuberculosis and Their Applications by Carlos Castillo-Chavez, Baojun Song

“…., TB co-infection with HIV/AIDS, drug-resistant TB, responsesof the immune system, impacts of demography, the role of publictransportation systems, and the impact of contact patterns. …”
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Improvement of non-alcoholic fatty liver disease treatment by P. I. Seliverstov, V. G. Radchenko

“…To estimate efficacy of combined hepatotropic drug «Hepaguard Active» for prevention of progression of non-alcoholic fatty liver disease (NAFLD) at steatosis stage.Material and methods. …”
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A Novel Approach on the Advancement in Polymer Phase Change Material in Solar Energy by G. Jegan, P. Ramani, T. J. Nagalakshmi, S. Chitra, T. Samraj Lawrence

“…Furthermore, the possible applications of polymer phase PCMs in a variety of fields, such as energy storage devices, thermal corrective action, and temperature-controlled drug carriers, are detailed. In this paper, a novel approach on the advancement of nanoconfined phase change material is defined along with the application of the solar energy system.…”
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Supraventricular Arrhythmias after Thoracotomy: Is There a Role for Autonomic Imbalance? by George Vretzakis, Marina Simeoforidou, Konstantinos Stamoulis, Metaxia Bareka

“…Their importance lies in the immediate hemodynamic consequences, the potential for systemic embolization and the consequent long-term need for prophylactic drug administration, and the increased cost of hospitalization. …”
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Autophagy in brain tumors: molecular mechanisms, challenges, and therapeutic opportunities by Jiarui Zhang, Jinan Zhang, Chen Yang

“…Autophagy mechanisms can influence metastasis and drug resistance in glioblastoma, and there is a complex interplay between autophagy and cellular responses to stress like hypoxia and starvation. …”
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Effects of Selected Antioxidants on Electroretinography in Rodent Diabetic Retinopathy by Radosław Dutczak, Marita Pietrucha-Dutczak

“…However, prolonging the drug exposure showed that the antioxidants could delay the onset of adverse changes but did not stop them. …”
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Factors influencing sleep disorders in perimenopausal women: a systematic review and meta-analysis by Weisi Zeng, Jialan Xu, Ying Yang, Meiling Lv, Xin Chu

“…The results of Meta-analysis showed that depression(OR = 2.73, 95%CI 1.65 ~ 4.52), hot flashes (OR = 2.70, 95%CI 1.81 ~ 4.02), chronic disease (OR = 1.39, 95%CI 1.24 ~ 1.56) and psychotropic drug use(OR = 3.19, 95%CI 1.31 ~ 7.77) were risk factors for sleep disorders in perimenopausal women (p < 0.05).ConclusionSleep disorder is one of the most common symptoms in perimenopausal women, and its influencing factors should be paid attention to. …”
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Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence by Suneel Kumar Garg, Omender Singh, Deven Juneja, Niraj Tyagi, Amandeep Singh Khurana, Amit Qamra, Salman Motlekar, Hanmant Barkate

“…Polymyxin B has resurged in recent years as a last resort therapy for Gram-negative multidrug-resistant (MDR) and extremely drug resistant (XDR) infections. Understanding newer evidence on polymyxin B is necessary to guide clinical decision making. …”
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Traumatic Page Kidney Induced Hypertension in Critical Care: Immediately Resolved or Long-Term Resistant Problem by E. Brotfain, L. Koyfman, A. Frenkel, A. Smolikov, A. Zlotnik, M. Klein

“…We discuss different therapeutical opportunities to extremely elevated systemic blood pressure resistant to traditional drug therapy.…”
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Behavioral Intervention versus Pharmacotherapy or Their Combinations in the Management of Overactive Bladder Dysfunction by Khanh Tran, Robert M. Levin, Shaker A. Mousa

“…Based on available literature, management of OAB using a combination of behavioral therapy and drug intervention is the most efficacious in terms of patient satisfaction, perceived improvement, and reduction of bladder symptoms. …”
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Mitochondrial abnormalities as a target of intervention in acute myeloid leukemia by Elissa Tjahjono, Megan R. Daneman, Bernadetta Meika, Alexey V. Revtovich, Natalia V. Kirienko

“…Further, we explore the combination strategy of mitophagy-targeting compounds with existing and/or novel chemotherapeutics to eradicate AML and discuss strategies to uncover new drug targets and novel mitochondria-targeting drugs.…”
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The introduction and inspiration from US FDA guidance: bacterial risk control strategies for blood collection establishments and transfusion services to enhance the safety and avai... by ZHANG Ningjie, YANG Yuanqing, ZHU Yuanpei, WANG Yongjun, GUO Yongjian

“…The risk of bacterial contamination of platelets is a leading risk of infection from blood transfusion. U.S. Food and Drug Administration recently issued a guidance on bacterial risk control strategies for blood collection establishments and transfusion services to enhance the safety and availability of platelets for transfusion. …”
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HIV Treatment as Prevention: Contradictory Perspectives from Dynamic Mathematical Models by Jing Wu, Jessie L. Norris, Yujiang Jia, Ning Wang

“…Some outcomes of dynamic models were based on unfeasible assumptions, such as no consideration of drug resistance, behavior disinhibition, or economic inputs in poor countries, and unrealistic input variables, for example, overstated initiation time, adherence, coverage, and efficacy of treatment. …”
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Linezolid and tedizolid adverse effects: a review on serotonin syndrome, myelosuppression, neuropathies, and lactic acidosis by Adam Greenfield, Erin Deja, Kimberly Lee, Sangeeta Sastry, Barry Rittmann

“…Mitigation strategies, including the role of therapeutic drug monitoring, are also discussed.…”
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