Exploiting CRISPR/Cas system in controlling antibiotic resistance of bacteria by Pourya Gholizadeh, Elnaz Faghfuri, Khudaverdi Ganbarov, Hossein Samadi Kafil

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The Quality of Inpatient Health Services at Mamajang Health Center, Makassar City by Lusyana Aripa

“…The results of the study: 1) Tangible, the facilities and infrastructure of the Mamajang Public Health Center inpatient room were inadequate. 2) Reliability, inpatient health services at the Mamajang Health Center are accurate. 3) Responsiveness, health workers have not been effective in responding to patient complaints but are always ready and efficient to help patients. 4) Assurance, trusted health workers in providing information, but the cure of the disease depends on the accuracy of the drug. 5) Empathy from health workers who care for patients. …”
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Reenvisioning Traditional to Regenerative Therapeutic Advances in Managing Nonalcoholic Fatty Liver Disease in Diabetes Mellitus by Lung-Wen Tsai, Yi-Hsiang Lu, Rajni Dubey, Jeng-Fong Chiou

“…These cellular therapies could be further complemented by platelet-derived biomaterials, TCM formulations, or any specific drug. Based on these abovementioned approaches, we aimed to comprehensively analyze various preclinical and clinical studies from traditional to regenerative therapeutic approaches in managing concomitant NAFLD and T2DM.…”
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Improvement of N-Acetylcysteine Loaded in PLGA Nanoparticles by Nanoprecipitation Method by Ruth Lancheros, Carlos A. Guerrero, Rubén D. Godoy-Silva

“…This research seeks to enhance the entrapment of NAC in PLGA nanoparticles for drug delivery systems. The nanoparticles were made using the nanoprecipitation method and changing the following parameters: the solvent/nonsolvent nature, its viscosity, pH, NAC addition to the nonsolvent, the polymer concentration and molecular weight, and NAC concentration in the solvent. …”
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Advances in RNA-Based Therapeutics: Challenges and Innovations in RNA Delivery Systems by Yuxuan Liu, Yaohui Ou, Linlin Hou

“…Nucleic acids, as carriers of genetic information, have found wide applications in both medical and research fields, including gene editing, disease diagnostics, and drug development. Among various types of nucleic acids, RNA offers greater versatility compared to DNA due to its single-stranded structure, ability to directly encode proteins, and high modifiability for targeted therapeutic and regulatory applications. …”
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Ensete ventricosum: A Multipurpose Crop against Hunger in Ethiopia by Getahun Yemata

“…Enset starch is found to have higher or comparable quality to potato and maize starch and widely used as a tablet binder and disintegrant and also in pharmaceutical gelling, drug loading, and release processes. Moreover, enset shows high genetic diversity within a population which in turn renders resilience and food security against the ever-changing environmental factors and land use dynamics. …”
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Intermittent Atrioventricular Block following Fingolimod Initiation by E. Gialafos, S. Gerakoulis, A. Grigoriou, V. Haina, C. Kilidireas, E. Stamboulis, E. Andreadou

“…We hypothesize that expression of this particular arrhythmia might be related to autonomic nervous system (ANS) dysfunction due to demyelinating lesions in the upper thoracic spinal cord, possibly augmented by the parasympathetic effect of the drug.…”
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Enantioselective Potentiometric Membrane Electrodes Based on Antibiotics for the Determination of L- and D-Glyceric Acids by Raluca-Ioana Stefan-van Staden, R'afat M. Nejem, Jacobus Frederick van Staden, Hassan Y. Aboul-Enein

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Bronchoscopic lung volume reduction complicated by ipsilateral pleural effusion by Marc Assaad, Wasif Shamsi, Anthony Loschner, Maria del Mar Cirino-Marcano

“…The use of both valves is approved by the Food and Drug Administration view their established efficacy in improving lung functions, quality of life and survival. …”
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Adropin as an indicator of T2DM and its complications by Hu Zhang, Ning Chen

“…Meanwhile, the strategies for promoting the secretion of adropin were also discussed, which will provide a target for the prevention and targeted treatment, or a candidate of novel and effective functional food or drug for metabolic diseases in the future.…”
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Diagnosing Sporadic Creutzfeldt-Jakob Disease in a Patient with a Suspected Status Epilepticus in the Intensive Care Unit by Harm J. van der Horn, Peter H. Egbers, Michaël A. Kuiper, Wouter J. Schuiling

“…A 53-year-old woman initially presenting with psychiatric symptoms developed myoclonus and was admitted 1 month later to the ICU with a suspected nonconvulsive status epilepticus and respiratory insufficiency, probably due to extensive antiepileptic drug therapy. Typical MRI and EEG findings and a positive 14-3-3 protein led to the diagnosis of sCJD. …”
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Successful Treatment of Hemophagocytic Lymphohistiocytosis Associated with Lupus Nephritis by Using Mycophenolate Mofetil by Takashi Nawata, Makoto Kubo, Kosaku Shiragami, Yukinori Nakamura, Masafumi Yano

“…This case suggests the possibility of mycophenolate mofetil as a key drug for treating HLH associated with SLE.…”
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A new biocompatible delivery scaffold containing heparin and bone morphogenetic protein 2 by Thanyaphoo Suphannee, Kaewsrichan Jasadee

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Acute Generalized Exanthematous Pustulosis Induced by Etanercept: Another Dermatologic Adverse Effect by Mukaddes Kavala, Ilkin Zindancı, Zafer Türkoglu, Burçe Can, Emek Kocatürk, Serkan Senol, Filiz Topaloglu

“…Acute generalized exanthematous pustulosis (AGEP) is a skin eruption that is primarily drug induced and characterized by the formation of numerous acute and sterile pustules on an erythematous background as mentioned by Weinblatt et al. (1999). …”
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Spectrophotometric Determination of Zidovudine in Pharmaceuticals Based on Charge-Transfer Complexation Involving N-Bromosuccinimide, Metol and Sulphanilic Acid as Reagents by K. Basavaiah, U. R. Anil Kumar

“…A simple spectrophotometric method is proposed for the determination of zidovudine(ZDV) in bulk drug and in pharmaceutical preparations. The method is based on the oxidation of ZDV by a known excess of oxidant N-bromosuccinimide (NBS), in buffer medium of pH 1.5, followed by the estimation of unreacted amount of oxidant with metol and sulphanilic acid. …”
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On Programmed Cell Death in Plasmodium falciparum: Status Quo by Dewaldt Engelbrecht, Pierre Marcel Durand, Thérèsa Louise Coetzer

“…We discuss the potential adaptive or nonadaptive role of PCD in the parasite life cycle and its possible exploitation in the development of novel drug targets. Lastly, we pose pertinent unanswered questions concerning the PCD phenomenon in P. falciparum to provide future direction.…”
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Role of the Kidneys in Resistant Hypertension by Z. Khawaja, C. S. Wilcox

“…Resistant hypertension is a failure to achieve goal BP (<140/90 mm Hg for the overall population and <130/80 mm Hg for those with diabetes mellitus or chronic kidney disease) in a patient who adheres to maximum tolerated doses of 3 antihypertensive drugs including a diuretic. The kidneys play a critical role in long-term regulation of blood pressure. …”
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An investigation of the dose-dependent safety of bemiparin sodium: A cell culture study by Emre Kubat, Ozer Aylin Gurpinar, Tuna Demirkiran

“…A control group was established with drug-free culture medium. Cell viability analysis was performed after 48 hours of incubation by the standard 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) method. …”
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Sexual Dysfunction and Hyperprolactinemia in Male Psychotic Inpatients: A Cross-Sectional Study by Erik Johnsen, Rune Kroken, Else-Marie Løberg, Eirik Kjelby, Hugo A. Jørgensen

“…Cross-sectional data were obtained at discharge from the hospital or 6 weeks after admittance for patients acutely admitted for psychosis and treated with a second-generation antipsychotic drug. Results. Half the patients reported diminished sexual desire and more than a third reported erectile and ejaculatory dysfunctions with no differences among the drugs. …”
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On physical analysis of topological indices and entropy measures for porphyrazine structure using logarithmic regression model by Asma Khalid, Shoaib Iqbal, Muhammad Kamran Siddiqui, Tariq Javed Zia, Brima Gegbe

“…Abstract The porphyrazine structure, known for its high chemical and thermal stability, has become a significant focus in materials science, chemical reactivity, functionalization, and drug design. By utilizing the new Zagreb-type indices to analyze the chemical structure of porphyrazine, we can gather more information about their bonding and connecting patterns. …”
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