Repurposing the Antidiabetic Drugs Glyburide, Gliquidone, and Glipizide in Combination with Benznidazole for <i>Trypanosoma cruzi</i> Infection by Citlali Vázquez, Rusely Encalada, Isabel Jiménez-Galicia, Rogelio Gómez-Escobedo, Gildardo Rivera, Benjamín Nogueda-Torres, Emma Saavedra

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Ezetimibe Anticancer Activity via the p53/Mdm2 Pathway by Charmy Twala, Sibusiso Malindisa, Chamone Munnik, Selisha Sooklal, Monde Ntwasa

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From the Criminalization of Substances to the “War on Drugs” Policy: A Century of Prohibitionism in Brazil by José Guilherme Magalhães e Silva, Luís Felipe Zilli, Letícia Godinho de Souza

Subjects: “…Drugs…”
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Santé et biens communs : un regard de juriste. by Isabelle Moine-Dupuis

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The Emergence of Extensively Drug-Resistant Tuberculosis (TB): TB/HIV Coinfection, Multidrug-Resistant TB and the Resulting Public Health Threat from Extensively Drug-Resistant TB, Globally and in Canada by Paul E Alexander, Prithwish De

“…Resistance to anti-tuberculosis (TB) drugs continues to present a major challenge to global public health. …”
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Inappropriate medication prescribing, polypharmacy, potential drug-drug interactions and medication regimen complexity in older adults attending three referral hospitals in Asmara, Eritrea: a cross-sectional study by Nuru Abdu, Saleh Idrisnur, Hanae Said, Lude Kifle, Natnael Habte, Semira Ghirmai, Tomas Tewelde, Senai Mihreteab Siele, Eyasu H. Tesfamariam

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Proximal tubule-on-chip as a model for predicting cation transport and drug transporter dynamics by Isy Petit, Quentin Faucher, Jean-Sébastien Bernard, Perrine Giunchi, Antoine Humeau, François-Ludovic Sauvage, Pierre Marquet, Nicolas Védrenne, Florent Di Meo

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Identification of Mutations that Encode Drug Resistance in the Polymerase Gene of the Human Immunodeficiency Virus by Zhengxian Gu, Hengsheng Fang, Horacio Salomon, Qing Gao, Mark A Wainberg

“…When the 65 and 184 mutations were combined into HXB2-D, the resultant construct did not possess higher levels of resistance lo any of these drugs than observed with the site 65 or 184 mutation alone. …”
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Recent Advances in Peptide-Loaded PLGA Nanocarriers for Drug Delivery and Regenerative Medicine by Hossein Omidian, Renae L. Wilson, Ana M. Castejon

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Drug therapy: dose-response relationship of oral mesalazine in inflammatory bowel disease by C. J. J. Mulder, S. J. Van Den Hazel

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On QSPR analysis of pulmonary cancer drugs using python-driven topological modeling by Huiling Qin, Mazhar Hussain, Muhammad Farhan Hanif, Muhammad Kamran Siddiqui, Zahid Hussain, Mohamed Abubakar Fiidow

Subjects: “…Pulmonary cancer drugs…”
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Editorial: Latest findings on Leishmania parasites for better vaccine design and drug development by Negar Seyed, Tahereh Taheri, Farhat Afrin, Hamidreza Majidiani, Hamidreza Majidiani

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Harnessing the AI/ML in Drug and Biological Products Discovery and Development: The Regulatory Perspective by Fahimeh Mirakhori, Sarfaraz K. Niazi

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Estimating Potential for Drug Budget Reallocation Following Expiration of Exclusivity of Pharmaceutical Products by Samira Toghanian, John Moshtaghi-Svensson, Maria Papageorgiou, Kristin Kittelsen, Christiaan Dolk, Markus Hultstrand, Stina Salomonsson

“…**Objectives:** This study investigated the impact of generic/biosimilar entry on drug budget in 4 countries. **Methods:** Pharmaceutical sales data, drug costs and LOE dates were modeled and forecast using an analytical framework (Affordability by ReallocaTing Funds model \[ART\]) to estimate future incremental budget availability using scenario analyses in Greece (GR), the Netherlands (NL), Norway (NO) and Sweden (SW). …”
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Evolution of drug therapy in patients with resectable gastric and esophageal‑gastric junction cancer by M. V. Sedova, M. A. Batov, V. S. Tretyak, A. A. Kolomeytseva, V. M. Khomyakov, N. N. Volchenko, A. A. Fedenko, A. D. Kaprin

“…International studies have shown the results of the use of targeted (ramucirumab, trastuzumab, pertuzumab), immune drugs (pembrolizumab, nivolumab, ipilimumab), S‑1 in combination with chemotherapy as part of the combined treatment of gastric and esophageal‑ gastric junction cancer. …”
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Does therapy with immunosuppressive drugs improve gastrointestinal symptoms in patients with systemic sclerosis? by Oliver Distler, Cosimo Bruni, Suzana Jordan, Carina Mihai, Muriel Elhai, Rucsandra Dobrota, Alexandru Garaiman, Mike Oliver Becker, Lea Stamm, Sherif Ismail, Norina Zampatti, Aurora Maria Tatu

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Optimization of HIV drugs through MCDM technique Analytic Hierarchy Process(AHP). by Fozia Bashir Farooq, Sobia Sultana, Nouf Abdulrahman Alqahtani, Muhammad Imran

“…Topological indices are crucial tools for predicting the physicochemical and biological features of different drugs. They are numerical values obtained from the structure of chemical molecules. …”
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Criteria to define rare diseases and orphan drugs: a systematic review protocol by Katie Kerr, Ghada Mohammed Abozaid, Amy McKnight, Hussain A Al-Omar

“…These conditions can be treated with medications known as orphan drugs (ODs). Unfortunately, there is no universal definition of RDs or ODs. …”
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Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II by V. Annapurna, G. Jyothi, T. Rohini Kumari, B. B. V. Sailaja

“…Simple, accurate and reproducible visible spectrophotometric method for the assay of drugs such as pyrilamine and fluvoxamine as maleates was established based on the formation of charge-transfer complex and redox reaction between the corresponding drug and substituted p-benzoquinone (chloranilic acid). …”
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Toxicology and Disease/Cancer Therapy in Reactive Oxygen Species-Mediated Drugs and Treatments by Hsueh-Wei Chang, Shao-Yu Chen, Li-Yeh Chuang, Sanjay Guleria

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