Low-Dose Taxol Promotes Neuronal Axons Extension and Functional Recovery after Spinal Cord Injury by Baoguo Liu, Sumei Liu, Dejun Sun

“…Taxol with proven clinical safety is commonly used as a broad-spectrum antitumor drug. Importantly, Taxol can promote axonal extension by enhancing and stabilizing the microtubule assembly. …”
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Digital Twins of Biological Systems: A Narrative Review by Ghufran A. Alsalloum, Nour M. Al Sawaftah, Kelly M. Percival, Ghaleb A. Husseini

“…The influence of DTs extends beyond healthcare and can revolutionize healthcare management, drug development, clinical trials, and various biomedical research fields…”
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Role of high-density lipoprotein cholesterol in health and diseases by Brijesh Yadav, Narayan Prasad

“…In this review, we have discussed the different property of high-density lipoprotein cholesterol, its function and factors influencing HDLc property in light of anti-inflammatory activity in rheumatoid arthritis and the role of cholesterol-lowering statin drug in enhancing the beneficial effect of high-density lipoprotein cholesterol in different cell types.…”
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Probiotics and Alcoholic Liver Disease: Treatment and Potential Mechanisms by Fengyuan Li, Kangmin Duan, Cuiling Wang, Craig McClain, Wenke Feng

“…Although many agents and approaches have been tested in patients with ALD and in animals with experimental ALD in the past, there is still no FDA (Food and Drug Administration) approved therapy for any stage of ALD. …”
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Studies on the Solute Solvent Interaction of Nimesulide in Aqueous Solutions of Hydrotropic Agents at Different Temperatures by Chandravir S. Solanki, Sushree Tripathy, Minaketan Tripathy, Upendra N. Dash

“…The present study deals with experiments so as to highlight the solute (drug nimesulide) - solvent(water) interactions and related modifications in case of the presence of hydrotropic agents at different temperatures T(=298.15 to 313.15)K. …”
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THALIDOMIDE AMELIORATES ERYTHROPOIESIS AND IRON HOMEOSTASIS IN TRANSFUSION-DEPENDENT β-THALASSEMIA by Kun Yang, Jian Xiao

“…This comprehensive study indicates that thalidomide treatment can ameliorate erythropoiesis and iron homeostasis in patients with TDT, thus supporting the effectiveness of this drug. …”
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Current developments in personalized treatment strategies for elderly acute myelogenous leukemia patients by Xueting Hou, Jizhang Bao

“…Acute myelogenous leukemia(AML) is a life-threatening hematologic malignancy that predominantly affects the elderly.Currently, chemotherapy and hematopoietic stem cell transplantation are the primary treatment modalities for AML, though their clinical application is limited in older patients.Recent years have seen the development of novel molecular targeted therapies, such as isocitrate dehydrogenase 1/2 (IDH1/2) and Feline macrophage stimulator-like tyrosine kinase 3 (FLT3) inhibitors, as well as individualized approaches like chimeric antigen receptor T-cell (CAR-T) therapy.However, due to patient heterogeneity and drug resistance, treatment outcomes for elderly AML remain unsatisfactory, underscoring the need for more precise and safer individualized treatment strategies.The combination of chemotherapy with novel targeted or immunotherapies shows promise as a future treatment direction.This research reviews the latest advances in the treatment of elderly AML, with a focus on achieving more individualized and safer therapeutic approaches.…”
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The Binding Affinity of Small Molecules with Yam Tyrosinase (Catechol Oxidase): A Biophysical Study by Tabassum Mulla, Sushama Patil, Srinivas Sistla, Jyoti Jadhav

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E3 Ubiquitin Ligases: Potential Therapeutic Targets for Skeletal Pathology and Degeneration by Ruiyin Zeng, Yuan Xiong, Ze Lin, Adriana C. Panayi, Yun Sun, Faqi Cao, Guohui Liu

“…Finally, this paper reviews the discovery of the relevant UPS inhibitors, drug molecules, and noncoding RNAs so far and prospects the future research and treatment.…”
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New Spectrophotometric and Conductometric Methods for Macrolide Antibiotics Determination in Pure and Pharmaceutical Dosage Forms Using Rose Bengal by Rania A. Sayed, Wafaa S. Hassan, Magda Y. El-Mammli, Abadalla Shalaby

“…The proposed methods were successfully applied for the determination of certain pharmaceutical dosage forms containing the studied drugs…”
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Solid-State FTIR Spectroscopic Study of Two Binary Mixtures: Cefepime-Metronidazole and Cefoperazone-Sulbactam by Hassan Refat H. Ali, Ramadan Ali, Hany A. Batakoushy, Sayed M. Derayea

“…This study provides data that can be used for the preparative process monitoring of the studied drugs in various dosage forms.…”
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substance use and recidivism of intimate partner violence in Peru: A cross-sectional study. by Victor Roman-Lazarte Sr., Enrique Moncada-Mapelli, Maryorie K Galeas-Torre, Luz A Roman, Maricela L Marcelo-Armas

“…Additionally, substance use (alcohol and drugs) is often associated with aggressive attitudes and serves as a risk factor for IPV…”
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M-Polynomials and Degree-Based Topological Indices of Triangular, Hourglass, and Jagged-Rectangle Benzenoid Systems by Young Chel Kwun, Ashaq Ali, Waqas Nazeer, Maqbool Ahmad Chaudhary, Shin Min Kang

“…Our results play a vital role in pharmacy, drug design, and many other applied areas.…”
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ACE Insertion/Deletion Polymorphism and Diabetic Nephropathy: Clinical Implications of Genetic Information by Sung-Kyu Ha

“…Besides the nongenetic factors, drug responses, can be influenced by ACE gene polymorphism. …”
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Piperacillin-Induced Immune Hemolytic Anemia in an Adult with Cystic Fibrosis by Mahesh Bandara, David B. Seder, George Garratty, Regina M. Leger, Jonathan B. Zuckerman

“…We report a case of drug-induced immune hemolytic anemia (DIIHA) in an adult female with cystic fibrosis (CF), complicating routine treatment of a pulmonary exacerbation with intravenous piperacillin-tazobactam. …”
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Curcumin phytosomal softgel formulation: Development, optimization and physicochemical characterization by Allam Ahmed N., Komeil Ibrahim A., Abdallah Ossama Y.

“…Phytosomal powder was characterized in terms of drug content and zeta potential. Thirteen different softgel formulations were developed using oils such as Miglyol 812, castor oil and oleic acid, a hydrophilic vehicle such as PEG 400 and bioactive surfactants such as Cremophor EL and KLS P 124. …”
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The controversies of parabens – an overview nowadays by Petric Zvonimir, Ružić Julia, Žuntar Irena

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Liquid Chromatographic Method for Determination of Nisoldipine from Pharmaceutical Samples by Amit Gupta, Ram S. Gaud, S. Ganga

“…The method was carried out at 320 nm after extraction of drug in methanol. The method uses aluminum plates pre-coated with silica gel 60F-254 as stationary phase and cyclohexane-ethyl acetate-toluene (3:3:4, v/v/v) as mobile phase. …”
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Tumor venéreo transmissível canino com resistência quimioterápica e metástase esplênica. Relato de caso by A. P. Duzanski, A. D. Ortiz, H. B. Fêo, M. W. Fonseca, M. M. Flórez, L. T Rodrigues, F. Michelon, N. S. Rocha

“…The tumor typically responds well to vincristine sulfate chemotherapy, although there are cases of resistance to the drug correlated with the tumoral phenotype. We describe herein a genital mixed TVTC case with metastases at spleen and failure at vincristine sulfate chemotherapeutic treatment in a five years old Australian Cattle Dog female. …”
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Prevalence of USA300 Colonization or Infection and Associated Variables During an Outbreak of Community-Associated Methicillin-Resistant Staphylococcus aureus in a Marginalized Urb... by Mark Gilbert, Judy MacDonald, Marie Louie, Dan Gregson, Kunyan Zhang, Sameer Elsayed, Kevin Laupland, Diane Nielsen, Virginia Wheeler, Tara Lye, John Conly

“…BACKGROUND: In 2004, an outbreak of the USA300 strain of methicillin-resistant Staphylococcus aureus (MRSA) was identified in persons with histories of homelessness, illicit drug use or incarceration in the Calgary Health Region (Calgary, Alberta). …”
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