Molecular Basis of Inhibitory Activities of Berberine against Pathogenic Enzymes in Alzheimer's Disease by Hong-Fang Ji, Liang Shen

“…These results have important implications for the berberine-based anti-AD drug design.…”
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A Sweet Potion to Put Embryonic Stem Cells to Sleep by Kaushik D. Deb

“…Human embryonic stem cells (hESCs) are rapidly revolutionizing the areas of drug screening and therapy. In view of their applications and high operational costs at global multicentric setups, the ability to store and transport hESCs and derivatives under ambient temperatures, and their cryopreservation without compromising the stemness, function, and viability, is becoming imperative. …”
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Sécurité sanitaire sous dépendance by Marie Coris, Alain Piveteau, Philippe Gorry, Matthieu Montalban

“…This is a new public policy challenge to which industrial policy must contribute independently of the traditional objective of improving competitiveness.We focus on the case of the drug industry to discuss this proposal. First, we note the emergence of a shortage of medicines in rich countries. …”
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The Food Safety Modernization Act of 2011 – Proposed Rule for Preventive Controls for Human Food by Soohyoun Ahn, Keith R. Schneider, Michelle D. Danyluk, Renee Goodrich-Schneider

“… The Food Safety Modernization Act (FSMA), which was signed into law by President Obama on January 4, 2011, is the most sweeping reform of food safety laws in more than 70 years since the enactment of the Federal Food, Drug and Cosmetic Act of 1938. High-profile foodborne outbreaks in the last decade and their impact on public health and the economy have exposed the need for a new, modern food safety system. …”
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Cellular Reprogramming toward the Erythroid Lineage by Laura J. Norton, Alister P. W. Funnell, Richard C. M. Pearson, Merlin Crossley

“…Currently, the main forms of treatment for these diseases are packed red blood cell transfusions and the administration of drugs which act to nonspecifically reactivate the production of foetal haemoglobin. …”
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A Review on Mangrove Actinobacterial Diversity: The Roles of Streptomyces and Novel Species Discovery by Jodi Woan-Fei Law, Priyia Pusparajah, Nurul-Syakima Ab Mutalib, Sunny Hei Wong, Bey-Hing Goh, Learn-Han Lee

“…The significant contribution of Streptomyces in microbial drug discovery as witnessed through the discovery of many important antibiotic drugs has undeniably encourage the exploration of these bacteria from different environments, especially the mangrove environments. …”
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Mycoplasma genitalium: An Emerging Sexually Transmitted Infection by Jessian L. Munoz, Oluwatosin Jaiyeoba Goje

“…Doxycycline, the first-line antibiotic for urethritis, is largely ineffective in the treatment of M. genitalium and furthermore, resistance to macrolide has also emerged. The most effective drug is Moxifloxacin although there are emerging reports of resistance to it in various parts of the world. …”
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New Onset Tinnitus after High-Frequency Spinal Cord Stimulator Implantation by Alexander V. Golovlev, Michael G. Hillegass

“…To further explore these less common neurologic complications of SCS therapy, a review of literature and a review of the U.S. Food and Drug Administration Manufacturer and User Facility Device Experience database are included. …”
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A mathematical model for antibiotic control of bacteria in peritoneal dialysis associated peritonitis by Colette Calmelet, John Hotchkiss, Philip Crooke

“…Using the model along with experimental data, clinical parameters, and physiological values, we compute variations in PD fluid distributions, drug concentrations, and number of bacteria in peritoneal and extra-peritoneal cavities. …”
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Presumed Tubercular Multifocal Choroiditis by Masoud Soheilian, Pejvak Azadi

“…The patient was started on a four-drug antituberculosis regimen. Six months later, the vision improved significantly to 20/30 in the right eye and finger counting at 6 meters in the left eye, with no remaining cellular reaction. …”
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Fibromyalgia: do I tackle you with pharmacological treatments? by Serge Perrot

“…Globally, pharmacological approaches are weakly effective but market authorization differs between Europe and United States. Food and Drug Administration–approved medications for fibromyalgia treatment include serotonin and noradrenaline reuptake inhibitors, such as duloxetine, and pregabalin (an anticonvulsant), which target neurotransmitter modulation and central sensitization. …”
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Pharmacogenetics of Chronic Pain and Its Treatment by Svatopluk Světlík, Karolína Hronová, Hana Bakhouche, Olga Matoušková, Ondřej Slanař

“…This paper reviews the impact of genetic variability of drug metabolizing enzymes, transporters, receptors, and pathways involved in chronic pain perception on the efficacy and safety of analgesics and other drugs used for chronic pain treatment. …”
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A Comprehensive Review on the Chemical Composition and Pharmacological Activities of Acacia catechu (L.f.) Willd. by Bikash Adhikari, Babita Aryal, Bibek Raj Bhattarai

“…Further research on diverse bioactive compounds from the plant is required to develop them as a successful potent drug.…”
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Simple Extractive Colorimetric Determination of Oxaprozin by Acid-Dye Complexation Methods in Solid Dosage Form by M. Ganesh, B. Thangabalan, Rahul Patil, Swastika Ganguly, T. Sivakumar

“…This method has been applied to the determination of drug in commercial tablets. Results of analysis were validated statistically. …”
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Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives by Prashant Kriplani, Pawan Swarnkar, Rinku Maheshwari, K. G. Ojha

“…All synthesized compounds were tested for their antibacterial activity using standard drug.…”
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Role of aspirin in cancer prevention by Meng Sun, Jun Yu, Jie Wan, Xiaoyun Dou, Xiaoying Chen, Fang Ye

“…Aspirin [1], also known as acetylsalicylic acid, is a common non-steroidal anti-inflammatory drug (NSAID). The available evidence shows that aspirin can effectively prevent and treat diseases such as rectal, gastric, ovarian, prostate, and lung cancer. …”
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Utility of N-Bromosuccinimide for the Titrimetric and Spectrophotometric Determination of Famotidine in Pharmaceutical Formulations by O. Zenita, K. Basavaiah

“…The applicability of the developed methods was demonstrated by the determination of FMT in pure drug as well as in tablets.…”
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Research progress on the role of extracellular vesicles in the pathogenesis of diabetic kidney disease by Jiangyuan Jin, Mianzhi Zhang

“…The purpose of this paper is to explain the potential diagnostic value of EVs in DKD, analyze the mechanism by which EVs participate in intercellular communication, and explore whether EVs may become drug carriers for targeted therapy to provide a reference for promoting the implementation and application of exosome therapy strategies in clinical practice.…”
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Silica Nanoparticles Effects on Blood Coagulation Proteins and Platelets by Volodymyr Gryshchuk, Natalya Galagan

“…Interaction of nanoparticles with the blood coagulation is important prior to their using as the drug carriers or therapeutic agents. The aim of present work was studying of the primary effects of silica nanoparticles (SiNPs) on haemostasis in vitro. …”
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Severe Agranulocytosis following Simultaneous Administration of Chlorpromazine and Trimethoprim-Sulfamethoxazole in a Patient with Sepsis: A Possible Toxic Combination by Anil Jha, Hassan Ghoz, Nicholas James

“…Either of those medications could cause fatal drug-induced agranulocytosis, with an unclear underlying mechanism. …”
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