Pain Management during Ultrasound Guided Transvaginal Oocyte Retrieval – A Narrative Review by Puvithra Thanikachalam, Dilip Kumar Govindan

“…As the procedure involves retrieving oocytes for in vitro fertilisation, the effect of the anaesthetic drugs on the oocyte quality should also be considered. …”
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Kinetics and Mechanism of Oxidation of t-Butylbenzylamine by Diperiodatoargentate(III) in Aqueous Alkali by Mahantesh A. Angadi, Suresh M. Tuwar

“…t-Butylbenzylamine (t-BA) is used as a free base in the synthesis of salbutamol drug. Its mechanism of oxidation was proposed from kinetic studies. …”
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The Use of Generic Medications for Glaucoma by Andrew J. Tatham

“…Other potential problems with generic eye drops include differences in bottle design affecting adherence, problems with supply, and the possibility that reduced revenue for innovator companies will lead to reduced investment in new drug development. This article reviews the potential advantages and disadvantages of generic antiglaucoma medications.…”
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COMPUTAÇÃO QUÂNTICA EM QUÍMICA by Caio M. Porto, Matheus S. Fonseca, Guilherme de S. T. Morais, Celso J. Villas-Boas, Rene A. Nome, Nelson H. Morgon

“…These collaborations pave the way for groundbreaking advancements in drug discovery and materials science. This research employed quantum computing simulators to investigate the potential energy surface (PES) of the H2 molecule at the CCSD/STO-3G level of theory. …”
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Two ways to one goal: new strategy of antiviral therapy for chronic hepatitis C by S. N. Batskikh

“…Triple therapy with induction phase strategy is recommended at application of boceprevir as the third agent. Another antiviral drug with direct action – telaprevir is recommended for prescription from first day of treatment.Conclusion. …”
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Antithrombotic Dilemmas after Left Atrial Appendage Occlusion Watchman Device Placement by Tania Ahuja, Scarlett Murphy, Daniel J. Sartori

“…We present a case of complex antithrombotic management, post LAAO device implantation, designed to avoid drug interactions with concomitant rifampin use and remained necessary secondary to subsequent device leak. …”
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Peroxisome Proliferator-Activated Receptors and the Heart: Lessons from the Past and Future Directions by Wang-Soo Lee, Jaetaek Kim

“…We also describe the results and lessons learned from important clinical trials on PPAR agonists and discuss the potential future directions for this class of drugs.…”
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The effectiveness of dexamethasone as a combination therapy for COVID-19 by Namazi Nader

“…Although variable efficacy of other combination therapies has been reported for treating COVID-19 associated with acute respiratory distress syndrome (ARDS), dexamethasone is an extensively used drug in many treatment regimens against COVID-19. …”
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Role of Shear Stress on Renal Proximal Tubular Cells for Nephrotoxicity Assays by Holly H. Birdsall, Timothy G. Hammond

“…Drug-induced nephrotoxicity causes huge morbidity and mortality at massive financial cost. …”
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The Food Safety Modernization Act of 2011 – Proposed Rule for Preventive Controls for Human Food by Soohyoun Ahn, Keith R. Schneider, Michelle D. Danyluk, Renee Goodrich-Schneider

“… The Food Safety Modernization Act (FSMA), which was signed into law by President Obama on January 4, 2011, is the most sweeping reform of food safety laws in more than 70 years since the enactment of the Federal Food, Drug and Cosmetic Act of 1938. High-profile foodborne outbreaks in the last decade and their impact on public health and the economy have exposed the need for a new, modern food safety system. …”
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A Whole-Food Plant-Based Diet Reversed Angina without Medications or Procedures by Daniele Massera, Tarique Zaman, Grace E. Farren, Robert J. Ostfeld

“…A 60-year-old man presented with typical angina and had a positive stress test. He declined both drug therapy and invasive testing. Instead, he chose to adopt a whole-food plant-based diet, which consisted primarily of vegetables, fruits, whole grains, potatoes, beans, legumes, and nuts. …”
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Applications of liposomes and lipid nanoparticles in cancer therapy: current advances and prospects by Zhe Cheng, Huichao Huang, Meilong Yin, Huaizheng Liu

“…Abstract Liposomes and lipid nanoparticles are common lipid-based drug delivery systems and play important roles in cancer treatment and vaccine manufacture. …”
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Protocols for translocation processes of flexible polymers through a pore using LAMMPS by Vrinda Garg, Rejoy Mathew, Arindam Chatterjee, Surya K. Ghosh

“…This protocol has potential applications in developing mathematical models for DNA sequencing, controlled drug delivery, and cellular transport processes.For complete details on the use and execution of this protocol, please refer to Garg et al.1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
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Addiction and Pain Medicine by Douglas Gourlay

“…Another factor that needs to be considered when assessing the practicality of prescribing medicinal cannabinoids is the difficulty in differentiating illicit from prescribed cannabinoids in urine drug testing. Overall, a thorough assessment of the risk/benefit profile of cannabinoids as they relate to a patient’s substance abuse history is suggested.…”
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Longstanding Eosinophilic Gastroenteritis of More Than 20 Years by Hugh J Freeman

“…Ketotifen provided symptomatic benefit, with prompt clinical relapse if the drug was discontinued. However, despite the use of ketotifen, the endoscopic abnormalities persisted and appeared to progress. …”
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BLINATUMOMAB IN THE THERAPY OF ACUTE B-LYMPHOID LEUKEMIA by Ugo Testa, Elvira Pelosi, Germana Castelli, Patrizia Chiusolo

“…Improved minimal residual disease (MRD)-negative response rates and long-term overall survival have been observed in B-ALL patients who received this drug. These therapeutic successes have led to FDA approval for refractory/relapsed and MRD-positive B-ALL patients. …”
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Inflammatory Bowel Disease Patients Are Frequently Nonadherent to Scheduled Induction and Maintenance Infliximab Therapy: A Canadian Cohort Study by Christopher Ma, Chad J Evaschesen, Grenvil Gracias, Vivian W Huang, Darryl K Fedorak, Karen I Kroeker, Levinus A Dieleman, Brendan P Halloran, Richard N Fedorak

“…Although infliximab has demonstrated efficacy in inducing and maintaining disease remission, adherence to regularly scheduled infliximab infusions is required to maintain therapeutic trough drug levels and prevent the development of anti-infliximab antibodies.…”
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Effect of neutrophils on tumor immunity and immunotherapy resistance with underlying mechanisms by Jiali Yao, Linlin Ji, Guang Wang, Jin Ding

“…Secondly, we review the mechanisms by which neutrophils affect drug resistance in tumor immunotherapy from the aspects of the immune microenvironment, tumor antigens, and epigenetics. …”
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Legal implications for the regulation of ownership, storage and control of narcotics in Indonesia by Hatarto Pakpahan, I Nyoman Nurjaya, Setiawan Nurdayasakti, Nurini Aprilianda

“…The purpose of this study is to examine the effects of the Narcotics Law Articles 111, 112, 117, and 122 on the use of drugs for recreational purposes, with focus on individuals who possess, store, and regulate narcotics. …”
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Autoantibodies and Liver Disease: Uses and Abuses by Marilyn V Zeman, Gideon M Hirschfield

“…In the continued absence of pathognomonic serum markers, diagnosis requires evaluation of laboratory investigations and, frequently, a liver biopsy – all of which need to be interpreted in the correct clinical context, with an emphasis on exclusion of viral infections, drug toxicity and metabolic disease. However, clear diagnosis is important for appropriate and timely therapy. …”
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