Recurrent Respiratory Papillomatosis Causing Chronic Stridor and Delayed Speech in an 18-Month-Old Boy by Adel Alharbi, Derek Drummond, Alfredo Pinto, Valerie Kirk

“…CO2 laser evaporation of papillomas and adjuvant drug therapy using lymphoblastoid interferon-alpha are the most common treatments. …”
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The treatment of irritable bowel syndrome from the modern views on the disease pathogenesis by Ye. A. Poluektova, S. Yu. Kuchumova, A. A. Sheptulin, V. T. Ivashkin

“…The treatment of the patients is based on the IBS clinical subtypes and include the antidiarrheal drugs, laxatives and spasmolytics. The good results were obtained during the administration of the combined drug Meteospasmyl (the combination of alverine citrate and simeticone). …”
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Milk-derived extracellular vesicles and gut health by Barathan Muttiah, Jia Xian Law

“…These findings underscore the promising role of milk-derived EVs in advancing GI health and therapeutics, paving the way for innovative approaches in oral drug delivery and targeted treatments for GI disorders.…”
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Single Photon Emission Tomography Imaging in Parkinsonian Disorders: A Review by Paul D. Acton, P. David Mozley

“…Imaging is now being utilised to elucidate the genetic contribution to Parkinson’s disease, and in longitudinal studies to assess the efficacy and mode of action of neuroprotective drug and surgical treatments. This review summarises recent applications of SPECT imaging in the study of parkinsonian disorders, with particular reference to the increasing role it is playing in the understanding, diagnosis and management of these diseases.…”
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Receptor-Mediated Endocytosis and Brain Delivery of Therapeutic Biologics by Guangqing Xiao, Liang-Shang Gan

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Acute Stent Thrombosis Associated with Eptifibatide-Induced Profound Thrombocytopenia by Amer Aljundi, Alaa Rahhal, Wafer Dabdoob

“…We describe a case of a 62-year-old female patient admitted with acute ST-elevation myocardial infarction (STEMI) treated by primary coronary intervention (primary PCI) with a drug-eluting stent placement. She developed profound thrombocytopenia within 8 hours of first administration of eptifibatide and subsequent acute stent thrombosis next day. …”
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Targeting secretory autophagy in solid cancers: mechanisms, immune regulation and clinical insights by Xinyu Li, Haiying Zhao

“…Moreover, substances released by secretory autophagy convey biological signals to the TME, inducing immune dysregulation and contributing to drug resistance. Therefore, elucidating the mechanisms underlying secretory autophagy is essential for improving clinical treatments. …”
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Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment by Walter Belda, Luiz Felipe Domingues Passero, Ana Thereza Stradioto Casolato

“…The classic treatment of sporotrichosis is performed with itraconazole or potassium iodide; second-line medications, such as amphotericin B and terbinafine, can alternatively be used in cases of first-line drug failure. In the present study, a patient with lymphocutaneous sporotrichosis in the right upper limb exhibited intolerance to itraconazole and potassium iodide, additionally during the period of use; these drugs did not control skin lesions. …”
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Synthesis and Biological Evaluation of Novel Piperazine Containing Hydrazone Derivatives by Betül Kaya, Yusuf Özkay, Halide Edip Temel, Zafer Asım Kaplancıklı

“…Galantamine was used as a standard drug.…”
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Stratégies argumentatives dans les discours politiques américains sur la législation des substances psychoactives : quel emploi du pathos à l’ère de la post-vérité ? by Sarah Bourse

“…The present study focuses on a corpus of political speeches about drug reform. The “War on Drugs” is a significant matter of public health that can be tackled from a medical or a criminal point of view. …”
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Influence of novel oral anticoagulants on anticoagulation care management by Janzic Andrej, Kos Mitja

“…Obtained information was further explored through the analysis of nationwide data of drug prescriptions and realization of health care services. …”
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Designing an exploratory phase 2b platform trial in NASH with correlated, co-primary binary endpoints. by Elias Laurin Meyer, Peter Mesenbrink, Nicholas A Di Prospero, Juan M Pericàs, Ekkehard Glimm, Vlad Ratziu, Elena Sena, Franz König, EU-PEARL NASH Investigators

“…Platform trials provide great benefits for sponsors and trial participants in terms of accelerating drug development programs. In this article, we describe some of the activities of the EU-PEARL consortium (EU Patient-cEntric clinicAl tRial pLatforms) regarding the use of platform trials in NASH, in particular the proposed trial design, decision rules and simulation results. …”
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Restenosis and Therapy by Laszlo Denes, Laszlo Entz, Veronika Jancsik

“…Gene therapy and therapeutic angiogenesis is proposed for therapy in restenosis. We suggest a drug candidate (iroxanadine), which ensures a noninvasive treatment by reverse regulation of the highly proliferating VSMCs and the disturbed function of ECs.…”
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One-Pot Synthesis of Novel Furochromone and Oxazocine Derivatives as Promising Antitumor Agents with Their Molecular Docking Studies by Rita M. Borik

“…The antitumor results suggested that furochromone derivatives 5a–h have activity against MCF7 in comparison with doxorubicin as the standard drug. Furthermore, the molecular docking studies of these novel derivatives of furochromone and oxazocine showed good agreement with the biological results when their binding pattern and affinity towards the active site of EGFR was investigate.…”
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Methotrexate-Associated Lymphoproliferative Disorder in a Patient with Psoriasis: A Case Report and Review of the Literature by Carolina Afonso, Adriana Roque, Cátia Almeida, Maria Beatriz Pimentão, Maria José Julião, Rodolfo Silva, Catarina Geraldes, Marília Gomes

“…Outside the posttransplant setting, methotrexate (MTX), a drug commonly used for the treatment of autoimmune diseases, is an immunosuppressive agent frequently reported to be associated with LPD. …”
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A Turn-On Fluorescent Sensor for Glutathione Based on Bovine Serum Albumin-Stabilized Gold Nanoclusters by Yan Qiu, Jianlin Huang, Li Jia

“…The fluorescence sensor successfully detected glutathione in commercial drug products.…”
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Unique Findings and Novel Treatment Strategy of a Giant Coronary Artery Aneurysm Associated with a Significant Pericardial Effusion by Osayi Lawani, Rick Ganim

“…We will also present its unusual repair using a long drug-eluting stent as a scaffold to overlap covered coronary stents used to help exclude the aneurysm.…”
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Conquering myositis, beyond remission by Amber O'Connor, T G Sundaram

“…Akin to a stowed sailboat, limiting management of chronic illnesses such as idiopathic inflammatory myopathies (IIM) to diagnosis, investigations, and drug prescriptions, is like leaving the seas unchartered. …”
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Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application by Romilly E. Hodges, Deanna M. Minich

“…Clinical applications to alter detoxification pathway activity and improve patient outcomes are considered, drawing on the growing understanding of the relationship between detoxification functions and different disease states, genetic polymorphisms, and drug-nutrient interactions. Some caution is recommended, however, due to the limitations of current research as well as indications that many nutrients exert biphasic, dose-dependent effects and that genetic polymorphisms may alter outcomes. …”
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Effects of Cosmetic Formulations Containing Hydroxyacids on Sun-Exposed Skin: Current Applications and Future Developments by Andrija Kornhauser, Sergio G. Coelho, Vincent J. Hearing

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