Alginate: Current Use and Future Perspectives in Pharmaceutical and Biomedical Applications by Marta Szekalska, Agata Puciłowska, Emilia Szymańska, Patrycja Ciosek, Katarzyna Winnicka

“…The focus of the paper is to describe biological and pharmacological activity of alginates and to discuss the present use and future possibilities of alginates as a tool in drug formulation. The recent technological advancements with using alginates, issues related to alginates suitability as matrix for three-dimensional tissue cultures, adjuvants of antibiotics, and antiviral agents in cell transplantation in diabetes or neurodegenerative diseases treatment, and an update on the antimicrobial and antiviral therapy of the alginate based drugs are also highlighted.…”
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Astrocytes Control Neuronal Excitability in the Nucleus Accumbens by Tommaso Fellin, Marcello D'Ascenzo, Philip G. Haydon

“…By integrating these results with the most recent evidence demonstrating the importance of astrocytes in the regulation of neuronal excitability, we propose that astrocytes are involved in mediating some of the mGluR5-dependent drug-induced behaviors.…”
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Cardiovascular Side Effects of Atomoxetine and Its Interactions with Inhibitors of the Cytochrome P450 System by Pashtoon Murtaza Kasi, Rawad Mounzer, George H. Gleeson

“…Here, we present a case of a patient who presented with syncope, orthostatic hypotension, and tachycardia and discuss the various clinical implications based on the pharmacokinetics and pharmacodynamics of the drug.…”
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Pharmacokinetics of Hyperthermic Intrathoracic Chemotherapy following Pleurectomy and Decortication by Paul H. Sugarbaker, O. Anthony Stuart, Christopher Eger

“…Our results showed a persistent high concentration of intrapleural drug as compared to plasma concentrations. The increased exposure for mitomycin C was 96, and the increased exposure for doxorubicin was 241. …”
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When Should a Patient with Statin-Induced Myopathy Be Re-challenged? A Case of Necrotizing Autoimmune Myopathy by Elena Obreja, Pamela Sequeira, Diana Girnita

“…Our case report offers an excellent source of “identification patterns” of muscular autoimmune disease which can be easily mistaken as common side effect of a drug.…”
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Sterile Endophthalmitis after Intravitreal Injections by Joaquín Marticorena, Vito Romano, Francisco Gómez-Ulla

“…Sterile endophthalmitis appears as an infrequent complication of intravitreal injections and seems to develop mainly in the context of the off-label use of drugs that have not been conceived for intravitreous administration. …”
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Nonbacterial Osteitis of the Clavicle: Longitudinal Imaging Series from Initial Diagnosis to Clinical Improvement by E. Roos, M. Maas, S. J. M. Breugem, G. R. Schaap, J. A. M. Bramer

“…Treatment of choice is a nonsteroidal anti-inflammatory drug. This case report gives a complete follow-up of the disease, showing the pitfalls of the diagnosis.…”
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Aspirin Resistance by Khaled Mansour, Ali T. Taher, Khaled M. Musallam, Samir Alam

“…The development of adverse cardiovascular events despite aspirin use has established an interest in a possible resistance to the drug. Several definitions have been set and various laboratory testing modalities are available. …”
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1,25-Vitamin D-mediated hypercalcaemia in the setting of immune therapy-related sarcoid-like reaction by R K Dharmaputra, N Sheriff, S Ravichandran

“…Further investigations demonstrated hilar lymphadenopathy, which was not present in previous imaging, and subsequent hypercalcaemia work-up demonstrated a significantly elevated serum calcitriol level as high as 429 pmol/L. A diagnosis of drug-induced sarcoid-like reactions or DISRs was made on the basis of hypercalcaemia and hilar lymphadenopathy following immunotherapy. …”
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Syntheses and Antibacterial Studies of Some 1-Phenyl-3-(4-(2-ethanoloxy) phenyl)-5-aryl-1H-pyrazoles by Anju Goyal, Sandeep Jain

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Amiodarone Pulmonary Toxicity by Norman Wolkove, Marc Baltzan

“…Amiodarone is an antiarrhythmic agent commonly used to treat supraventricular and ventricular arrhythmias. This drug is an iodine-containing compound that tends to accumulate in several organs, including the lungs. …”
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RNA Biopesticides: A Cutting‐Edge Approach to Combatting Aquaculture Diseases and Ensuring Food Security by Qiu Li, Lixing Huang

“…Traditional pharmaceuticals struggle with drug resistance and environmental harm, raising food safety concerns due to chemical residues. …”
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Rapid Diagnosis of Malaria by Clinton K. Murray, Jason W. Bennett

“…Implementation of prompt and accurate diagnosis is needed to curb the expanding global impact of malaria associated with ever-increasing antimalarial drug resistance. Traditionally, malaria is diagnosed using clinical criteria and/or light microscopy even though both strategies are clearly inadequate in many healthcare settings. …”
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Using Mathematical Modeling as a Resource in Clinical Trials by Evans K. Afenya

“…In the case of dose-dense treatment along with recombinant hematopoietic growth factors, the models predict a situation in which normal and abnormal cells in the marrow and peripheral blood are obliterated by drug action, while the normal cells regain their growth capabilities through growth-factor stimulation.…”
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Immune Thrombocytopenia in a Child with T Cell Lymphoblastic Lymphoma by Kayo Tokeji, Sachi Sakaguchi, Tomoko Kurimoto, Junya Fujimura, Toshiaki Shimizu

“…The underlying mechanism of ITP with NHL is still unclear. Drug-induced immunomodulation with a reduction of regulatory T cells might have contributed to the development of ITP in our case.…”
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Review on bacterial outer membrane vesicles: structure, vesicle formation, separation and biotechnological applications by Xiaofei Zhao, Yusen Wei, Yuqing Bu, Xiaokai Ren, Zhanjun Dong

“…Furthermore, the review highlights the burgeoning applications of OMVs in the field of biomedicine, emphasizing their potential as diagnostic tools, vaccine candidates, and drug delivery vectors.…”
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Application of DNA Array Technology for Diagnostic Microbiology by Stephanie A Booth, Michael A Drebot, Graham A Tipples, Lai King Ng

“…Microarrays or DNA chips have been hailed as the ultimate experimental tool for research, drug discovery and diagnostics. They have the potential to perform a multitude of molecular tests simultaneously and to produce a wealth of information from a single clinical sample. …”
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The Fruit Malus prunifolia (Malus micromalus Mak.): A Minireview of Current Knowledge of Fruit Composition and Health Benefits by Xiaolong Ji, Chunyan Hou, Xudan Guo

“…This minireview could be useful for predicting its other medicinal uses and its potential drug or food interactions, and it could be beneficial for people living in areas where the fruit is endemic and where healthcare resources are scarce.…”
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Mechanisms and diagnosis of myocardial ischemia in patients with intact coronary arteries by V.A. Skybchyk, Yu.P. Melen

“…The information obtained during the invasive diagnostic procedure allows to determine the appropriate endotype of INOCA in order to make a correct diagnosis and prescribe effective drug treatment improving prognosis and quality of life.…”
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Molecular optimization using a conditional transformer for reaction-aware compound exploration with reinforcement learning by Shogo Nakamura, Nobuaki Yasuo, Masakazu Sekijima

“…Abstract Designing molecules with desirable properties is a critical endeavor in drug discovery. Because of recent advances in deep learning, molecular generative models have been developed. …”
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