Alleviating effects and mechanisms of action of large-leaf yellow tea drinking on diabetes and diabetic nephropathy in mice by Guangshan Zhao, Jianyuan Teng, Ruixia Dong, Qiuyan Ban, Lian Yang, Kang Du, Yifei Wang, Hanlin Pu, Chung S. Yang, Zhe Ren

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Rapid Determination of Pemetrexed Concentration and Distribution in Human Breast Cancer Cells (McF-7) Based on UHPLC-MS/MS by Mengwei Zhang, Zhipeng Wang, Qiqiang Zhang, Qing Ye, Fengjing Xu, Lili Cui, Yanping Liu, Shouhong Gao, Wansheng Chen, Yan Liu

“…The study of intracellular drug concentration distribution is helpful to understand the drug efficacy of target site. …”
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The diagnostic value and efficacy evaluation of lung ultrasound score in neonatal respiratory distress syndrome: a prospective observational study by Jian Dong, Yuhong Deng, Jin Tong, Tingting Du, Wenguang Liu, Yan Guo

“…Each patient underwent both the 14-zone and 12-zone lung ultrasound methods, as well as a chest x-ray, performed after birth and before initiating drug treatment. Surfactant replacement therapy was administered to patients who were diagnosed with neonatal respiratory distress syndrome and met the criteria for medication. …”
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Antibiotic and Disinfectant Susceptibility Patterns of Bacteria Isolated from Farmed Fish in Kirinyaga County, Kenya by Daniel W. Wanja, Paul G. Mbuthia, Robert M. Waruiru, Lilly C. Bebora, Helena A. Ngowi, Philip N. Nyaga

“…However, intensive and indiscriminate use of antimicrobials has led to increased occurrence of drug resistance in pathogenic bacteria, as well as normal flora. …”
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Synthesis, X-Ray Crystal Structures, Biological Evaluation, and Molecular Docking Studies of a Series of Barbiturate Derivatives by Assem Barakat, Hazem A. Ghabbour, Abdullah Mohammed Al-Majid, Qurat-ul-ain, Rehan Imad, Kulsoom Javaid, Nimra Naveed Shaikh, Sammer Yousuf, M. Iqbal Choudhary, Abdul Wadood

“…Compounds 4c, 4h, 4o, 4p, 4q, 5f, and 5m were found to be potent α-glucosidase inhibitors and showed more activity than the standard drug acarbose, whereas compounds 4v, and 5h were found to be potent thymidine phosphorylase inhibitors, more active than the standard drug, 7-deazaxanthine. …”
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The Association between Type-2 Diabetes Duration and Major Adverse Cardiac Events after Percutaneous Coronary Intervention by Botey Katamu Benjamin, Chunguang Qiu, Zhanying Han, Wenjie Lu, Guoju Sun, Xiaofei Qin, Xule Wang, Xi Wang, Ran Li, Liang Pan

“…A total of 302 cases of diabetic patients undergoing an elective PCI with drug-eluting stent (DES) deployment and or percutaneous transluminal coronary angioplasty (PTCA) using a drug-coated balloon (DCB) were prospectively studied. …”
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Assessment of synergistic efficacy of carbaryl in combination with Cinnamomum cassia and Origanum vulgare essential oils against Dermanyssus gallinae by Zhonghao Wang, Kai Xu, Shuo Yin, Jing Liu, Jianhua Qin, Dehe Wang, Lijun Xu, Chuanwen Wang

“…However, the escalating drug resistance due to sustained reliance on chemical acaricides highlights the urgent need for new mite management strategies. …”
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A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment o... by Yan Gong, James Rogers, Christian Friedrich, Sanjay Patel, Alexander Staab, Jorge Luiz Gross, Daniel Polhamus, William Gillespie, Brigitta Ursula Monz, Silke Retlich

“…Based on an example evaluating HbA1c reduction with linagliptin versus sitagliptin, the model used seems a valid approach for indirect drug comparisons.…”
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Real-world treatment patterns of patients with acute coronary syndrome based on 15-year data by Inga S. Egorova, Natalia N. Vezikova

“…The clinical features, drug therapy, reperfusion interventions, complication rate, outcomes, and mortality were evaluated. …”
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Helicobacter pylori infection at long-term treatment by proton pump inhibitors for acid-related diseases (Literature review and resolution of Advisory council, March 22, 2018) by V. T. Ivashkin, I. V. Mayev, R. A. Abdulkhakov, O. P. Alekseyeva, S. A. Alekseyenko, A. Yu. Baranovsky, Ye. K. Baranskaya, I. L. Klyaritskaya, N. V. Korochanskaya, Yu. A. Kucheryavy, T. L. Lapina, M. F. Osipenko, V. I. Simanenkov, G. N. Tarasova, A. S. Trukhmanov, I. B. Khlynov, A. A. Sheptulin

“…The choice of specific PPI for treatment of patients with GERD and other acid-related diseases, carrying out H. pylori eradication therapy or substitution of one PPI agent to another are individualized and depend on the indications registered in the drugs administration instructions, features of its pharmacokinetics and pharmacodynamics, possible drug-to-drug interactions. …”
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7-Day Nonbismuth-Containing Concomitant Therapy Achieves a High Eradication Rate for Helicobacter pylori in Taiwan by Sung-Shuo Kao, Wen-Chi Chen, Ping-I Hsu, Kwok-Hung Lai, Hsien-Chung Yu, Hui-Hwa Cheng, Nan-Jing Peng, Chiun-Ku Lin, Hoi-Hung Chan, Wei-Lun Tsai, Huay-Min Wang, Tzung-Jiun Tsai, Kung-Hung Lin, Feng-Woei Tsay

“…Patients were asked to return at the second week to assess drug compliance and adverse effects. Repeated endoscopy or urea breath test was performed at 8 weeks after the end of eradication therapy. …”
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Effect of Staggered vs. Simultaneous Co-Administration of Bempedoic Acid on Pharmacokinetics of Pravastatin: Randomized, Cross-Over Clinical Trial in Healthy Volunteers by Felicitas Stoll, Salvatore Amato, Max Sauter, Jürgen Burhenne, Johanna Weiss, Walter E. Haefeli, Antje Blank

“…We hypothesized that the drug interaction between BA and statins could be mitigated by staggered administration. …”
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Development of the therapeutic regimen based on the synergistic activity of cyclophosphamide and double-stranded DNA preparation which results in complete cure of mice engrafted wi... by E. A. Potter, E. V. Dolgova, A. S. Proskurina, Ya. R. Efremov, O. S. Taranov, V. P. Nikolin, N. A. Popova, T. D. Dubatolova, D. D. Petrova, E. I. Vereschagin, A. M. Minkevich, O. M. Andrushkevich, S. I. Baiborodin, V. A. Rogachev, A. A. Ostanin, E. R. Chernykh, N. A. Kolchanov, S. S. Bogachev

“…We performed quantitative analysis of TISC dynamics in Krebs-2  ascites following treatment with the cytostatic drug cyclophosphamide (CP) and untreated control cells. …”
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A De Novo Frameshift Variant in SMC1A Causes Non‐Classic Cornelia de Lange Syndrome With Epilepsy: A Case Report and Literature Review by Ying Yang, Liqing Chen, Zhenzhen Wang, Yaling Ding, Yan Liu

“…Regarding epilepsy characteristics, some individuals including seizure clusters, status epilepticus, drug resistance, and hypotonia, no significant differences were observed between classic and non‐classic cases. …”
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Identification of promising SARS-CoV-2 main protease inhibitor through molecular docking, dynamics simulation, and ADMET analysis by Ganesh Sharma, Neeraj Kumar, Chandra Shekhar Sharma, Taha Alqahtani, Yewulsew Kebede Tiruneh, Sharifa Sultana, Gabriel Vinícius Rolim Silva, Gabriela de Lima Menezes, Magdi E. A. Zaki, Jonas Ivan Nobre Oliveira

“…The binding energy was comparable to that of the reference drug X77, indicating potential efficacy. Molecular dynamics simulations over 300 ns confirmed the stability of the Mpro/4896 − 4038 complex of protein-ligand. …”
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Research progress on medication literacy of elderly cancer patients during oral chemotherapy (老年肿瘤患者口服化疗药物期间药物素养研究进展) by LIU Yin (柳吟), SHI Ruchun (施如春), HUANG Jun (黄君), ZHAO Hongxia (赵红霞), QIU Minyan (邱敏燕), SHEN Xiaoyan (沈晓燕)

“…Drug therapy is the main treatment for elderly cancer patients. …”
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The Emerging Role of Nanomedicine in the Management of Nonalcoholic Fatty Liver Disease: A State-of-the-Art Review by Seyedeh Alia Moosavian, Thozhukat Sathyapalan, Tannaz Jamialahmadi, Amirhossein Sahebkar

“…Employing nanoparticles as a drug delivery system has demonstrated significant potential for improving the bioavailability of drugs in the treatment of NAFLD. …”
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Magnetic Nanoparticles for Targeting and Imaging of Stem Cells in Myocardial Infarction by Michelle R. Santoso, Phillip C. Yang

“…Other fields have successively used nanoscience and nanotechnology for a multitude of biomedical applications, including drug delivery, targeted imaging, hyperthermia, and tissue repair. …”
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Chlorambucil-Induced Acute Interstitial Pneumonitis by Hammad Shafqat, Adam J. Olszewski

“…Clinicians should consider drug-induced interstitial pneumonitis in the differential diagnosis of a suggestive syndrome developing even after discontinuation of chlorambucil.…”
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Duodenal Peptic Ulcer Perforation in the Puerperium Case Report Series by Elizabeth Stiles, Andre Robinson, Erin Fitzgerald, Marie Fleury, Andrew Rubenstein

“…We present two case reports of primigravida, advanced maternal age females with history of irritable bowel syndrome and nonsteroidal anti-inflammatory drug (NSAID) use found to have perforated duodenal ulcers after Cesarean section. …”
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