Editorial: Host-diet-microbiome interactions in obesity prevention and treatment by Javad Barouei, Javad Barouei, Mary E. Kable, Mahta Moussavi, Mahta Moussavi, Yu-Hsin Hsieh

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Noise-Induced Hearing Loss: Updates on Molecular Targets and Potential Interventions by Huanyu Mao, Yan Chen

“…New pharmaceuticals targeting oxidative stress, inflammation, or noise-induced neuropathy are emerging, highlighted by the nanoparticle-based drug delivery system. Given the complexity of the pathogenesis behind NIHL, deeper and more comprehensive studies still need to be fulfilled.…”
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Avian Bornaviral Ganglioneuritis: Current Debates and Unanswered Questions by Su L. Boatright-Horowitz

“…At this time, numerous questions remain unanswered regarding the transmission of the disease, best practices for diagnostic sampling and testing, and whether currently used drug therapies are effective or harmful for afflicted birds. …”
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Development, Estimation and Validation of Lisinopril in Bulk and its Pharmaceutical Formulation by HPLC Method by V. Bhaskara Raju, A. Lakshmana Rao

“…An accurate and precise HPLC method was developed for the determination of lisinopril. Separation of the drug was achieved on a reverse phase C8 column using a mobile phase consisting of phosphate buffer and methanol in the ratio of 35:65v/v. …”
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Takayasu arteritis by N.V. Bortnyak, O.A. Yepanchintseva, A.V. Khokhlov, B.M. Todurov

“…The issues of the contemporary drug therapy, interventional and surgical treatment methods and complications of the disease are presented.…”
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Challenges faced during antitubercular therapy by B. K. Likhitha, Shreeshail Anjutagi, Keertivardhan D. Kulkarni, Madhav Mahawar

“…This case report discusses regarding a 48-year-old male with drug-sensitive tuberculosis (TB) and alcoholic liver disease, who experienced significant side effects during antitubercular therapy. …”
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Synthesis and Analgesic Activity of Novel Derivatives of 1,2-Substituted Benzimidazoles by Shobhit Srivastava, S. N. Pandeya, Meena K. Yadav, B. K. Singh

“…Some of these compounds showed promising analgesic activity when compared with the standard drug diclofenac sodium. The incorporation of a phenylhydrazinomethyl nucleus at 2-position of benzimidazole compound gave a biologically active pharmacophore.…”
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Spray-Dried Griseofulvin-Lactose Matrix for Enhanced Solubility Using a Spray-Drying Biochemical Process by Tian Lan, Jie Yang, Zhi-jie Yang, Hong-wen Wu

“…Griseofulvin (GF) is a hydrophobic drug with a low solubility. In order to improve the solubility of GF, which has low water solubility, this report uses the spray-drying technique to prepare complexes with lactose to promote the solubility and oral bioavailability of GF. …”
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Empowering Family Physicians to Impart Proper Inhaler Teaching to Patients with Chronic Obstructive Pulmonary Disease and Asthma by Janice M Leung, Mohit Bhutani, Richard Leigh, Dan Pelletier, Cathy Good, Don D Sin

“…BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) and asthma depend on inhalers for management, but critical errors committed during inhaler use can limit drug effectiveness. Outpatient education in inhaler technique remains inconsistent due to limited resources and inadequate provider knowledge.…”
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Chimie des substances naturelles et pharmacie : à la croisée des chemins by Beniddir, Mehdi A., Poupon, Erwan

“…An overview of the importance of natural products in pharmacy and drug discovery is provided herein. This “account” article seeks to shed light on current issues and challenges, through a critical analysis ranging from bioprospecting to the marketing of new drugs.…”
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Maintenance Electroconvulsive Therapy in a Patient with Treatment-Resistant Paranoid Schizophrenia and Comorbid Epilepsy by Beppe Micallef-Trigona, Joseph Spiteri

“…The treatment of choice for acute schizophrenia is antipsychotic drug treatment and electroconvulsive therapy (ECT) and should only be considered as an option for treatment-resistant schizophrenia, where treatment with clozapine has already proven ineffective or intolerable. …”
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Increased Sensitivity to Serotonin Syndrome in Cerebral Palsy by Adam Schindzielorz

“…Serotonin syndrome is characterized by symptoms of neuromuscular and autonomic excitation and altered mental status. It is most often drug induced with antidepressants being the main precipitants. …”
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A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab by Ted George Achufusi, Prateek S. Harnee, Sekou Rawlins

“…Recently, there has been increasing controversy regarding potential adverse effects of the drug especially in those with underlying inflammatory bowel disease. …”
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Increased Anxiety, Akathisia, and Suicidal Thoughts in Patients with Mood Disorder on Aripiprazole and Lamotrigine by Milena Pereira Pondé, Antonio Carlos Cruz Freire

“…The appearance of these limiting side effects requires discontinuation of the drug.…”
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A brief agricultural history of cannabis in Africa, from prehistory to canna-colony by Chris S. Duvall

“…Third, twentieth-century drug laws changed the economics of production, causing cannabis farming to become particularly attractive to resource-poor farmers. …”
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Double Vessel Coronary Angioplasty in a Patient with Anomalous Single Coronary Artery Arising from the Right Cusp and Premature Atherosclerotic Coronary Artery Disease: A Case Repo... by Varun Kumar, Shalini Gupta, Krishna Prasad

“…The patient managed successfully by percutaneous coronary interventions (PCI) with drug-eluting stents (DESs) by radial approach.…”
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The use of oral topically acting glucocorticosteroids in the treatment of inflammatory bowel disease by P. Rutgeerts

“…Glucocorticosteroids are the mainstay of treatment of active Crohn's disease and ulcerative colitis. These drugs however carry important cosmetic short-term side effects and when used long-term they induce severe irreversible complications. …”
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The Bioactivities of Phycocyanobilin from Spirulina by Yi Li

“…Due to the above biological activities of phycocyanobilin PCB, it is expected to become a new effective drug for treating various diseases, such as COVID-19 complications, atherosclerosis, multiple sclerosis (MS), and ischaemic stroke (IS).…”
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Atypical Histiocyte-Rich Sweet’s Syndrome by Sharon Chi, Marcia Leung, Mark Carmichael, Michael Royer, Sunghun Cho

“…Sweet’s Syndrome is a rare neutrophilic dermatosis thought to be a result of immune dysregulation occurring in the setting of drug exposure, recent infection, pregnancy, and underlying malignancy or idiopathic with specific and widely accepted diagnostic criteria established in the literature. …”
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The hidden economic and environmental costs of antimicrobial therapies: a call to action by Mildred Nelson, Sarah B. Green, Sujit Suchindran, Lucy S. Witt

“…The overuse and inappropriate use of antimicrobials have led to environmental waste and drug shortages. This challenges the ecological and economical sustainability of our healthcare system and worsens antimicrobial resistance.…”
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