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3901
Polypharmacy and anticholinergic burden scales in older adults: a cross-sectional study among psychiatric outpatients in a tertiary care hospital
Published 2025-01-01“…Polypharmacy was also positively associated with adverse drug reactions (Odds Ratio = 1.81; 95% Confidence Interval = 1.27–2.56). …”
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3902
Effect of Exogenous Melatonin Administration in Critically Ill Patients on Delirium and Sleep: A Randomized Controlled Trial
Published 2020-01-01“…RASS scores were 1 in both groups at baseline, compared to zero (drug group) and 0.5 (placebo group) posttreatment. …”
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3903
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3904
Synthesis and evaluation of nitrochromene derivatives as potential antileishmanial therapeutics through biological and computational studies
Published 2025-01-01“…Additionally, the growing issue of drug resistance presents a formidable challenge, further complicating disease management and control efforts. …”
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3905
Association Between Diabetic Control And Anti-Diabetic Medication Adherence Using 8-Point Morisky Medication Adherence Scale In Local Population Of Khyber Pakhtunkhwa
Published 2023-06-01“… Abstract: Background: Drug adherence to medications in diabetes is very necessary for strict glycemic control. …”
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3906
Knowledge, attitudes and practices of Australian dairy goat farmers towards the control of gastrointestinal parasites
Published 2025-01-01“…An indiscriminate use of antiparasitic drugs, primarily registered for use in sheep and cattle, in goats has resulted in drug-resistant gastrointestinal parasites. …”
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3907
Haemophagocytic lymphohistiocytosis in patients treated with immune checkpoint inhibitors: analysis of WHO global database of individual case safety reports
Published 2019-05-01“…The main outcome measures were co-suspected drugs, concurrent irAEs, HLH clinical, haematological and coagulation features, concomitant infections, HLH median time to onset and outcome.Results Among 49′883 ICI-related ADRs collated in VigiBase as of September 30th, 2018, HLH was reported in 38 cases of which 34 (90%) mentioned ICIs as the solely suspected drugs. …”
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3908
Economic impact of potentially inappropriate prescribing and related adverse events in older people: a cost-utility analysis using Markov models
Published 2019-01-01“…Objectives To determine the economic impact of three drugs commonly involved in potentially inappropriate prescribing (PIP) in adults aged ≥65 years, including their adverse effects (AEs): long-term use of non-steroidal anti-inflammatory drugs (NSAIDs), benzodiazepines and proton pump inhibitors (PPIs) at maximal dose; to assess cost-effectiveness of potential interventions to reduce PIP of each drug.Design Cost-utility analysis. …”
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3909
Wilson and Walker's Principles and Techniques of Biochemistry and Molecular Biology /
Published 2018Table of Contents: “…Biochemical and molecular biological methods in life sciences studies -- Basic principles -- Cell culture techniques -- Recombinant DNA techniques and molecular cloning -- Preparative protein biochemistry -- Electrophoretic techniques -- Immunochemical techniques -- Flow cytometry -- Radioisotope techniques -- Principles of clinical biochemistry -- Microscopy -- Centrifugation and ultracentrifugation -- Spectroscopic techniques -- Basic techniques probing molecular structure and interactions -- Mass spectrometric techniques -- Fundamentals of bioinformatics -- Fundamentals of chemoinformatics -- The python programming language -- Data analysis -- Fundamentals of genome sequencing and annotation -- Fundamentals of proteomics -- Fundamentals of metabolomics -- Enzymes and receptors -- Drug discovery and development.…”
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3910
Acute generalized exanthematous pustulosis induced by ceftriaxone with positive patch testing
Published 2024-02-01“…In over 90% of patients it is an adverse reaction to drugs. Delayed-type (type IV) hypersensitivity seems to play an important role in its pathophysiology. …”
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3911
Fifteen Percent Thermal Burn Injury Developing Severe Acute Respiratory Distress Syndrome
Published 2025-01-01“…Pneumonia and sepsis are the most common causes followed in incidence by aspiration of gastric contents, trauma, multiple transfusions, and drug overdose. Here, we report a case of 15% total body surface area 2nd-degree thermal burn injury developing severe ARDS, which was managed successfully. …”
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3912
Hantavirus Pulmonary Syndrome: Report of Four Alberta Cases
Published 1995-01-01“…A recent open label trial has not supported the efficacy of this drug. The epidemiology of Peromyscus maniculatus, the primary rodent host, and the clinical features of this syndrome are summarized.…”
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3913
Urticarial Vasculitis-Associated Intestinal Ischemia
Published 2016-01-01“…UV is often idiopathic but can also present in the context of autoimmune disorders such as systemic lupus erythematosus, drug reactions, infections, or a paraneoplastic syndrome. …”
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3914
A Study on L-Asparaginase of Nocardia levis MK-VL_113
Published 2012-01-01“…An enzyme-based drug, L-asparaginase, was produced by Nocardia levis MK-VL_113 isolated from laterite soils of Guntur region. …”
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3915
Fluticasone Propionate in Inflammatory Bowel Disease
Published 1990-01-01“…In particular, fluitcasone propionate is a fluorinated glucocorticoid, in which systemic side effects are absent or minimal due to its relatively low absorption and rapid first pass metabolism In an open trial in 12 patients with mild and moderately active Crohn's disease, administration of 20 mg fluitcasone propionate orally was associated with a significant fall in the Crohn's disease activity index and improvement in other parameters of inflammation, without change in either plasma cortisol levels or responsiveness to adrenocorticotropic hormone, suggesting that this drug is a promising therapy for Crohn's disease meriting evaluation against conventional corticosteroids.…”
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3916
Hemothorax due to Ruptured Mycotic Aneurysm of Intercostal Arteries Associated with Infective Endocarditis
Published 2017-01-01“…We present a case of hemothorax due to ruptured mycotic aneurysm in three intercostal arteries in a 40-year-old male with methicillin-resistant Staphylococcus aureus infective endocarditis (IE) due to intravenous drug use. Microcoil embolization and thoracotomy successfully achieved hemostasis. …”
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3917
Opium the Best Remedy
Published 2004-01-01“…As can be seen from his text, they were about whether the drug was available in adequate preparations, whether there was any difference between opium and other narcotics, particularly comparing the natural juice with "its artificial preparations" (1) (all of which he thought to be about equal in effect), whether it was stimulant or restorative and invigorating, and whether it was being properly used for all the conditions in which it could be helpful. …”
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3918
Antibacterial Activity of Grepafloxacin
Published 1998-01-01“…Its pharmacodynamic profile against pneumococci is promising, favouring use of this drug for respiratory tract infections.…”
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3919
Human infective endocarditis and septic shock caused by Streptococcus suis serotype 1
Published 2025-01-01“…Early diagnosis and selection of the correct antibiotic treatment according to the drug sensitivity is very important. If the infection causes damage to the structure of the body’s mitral valve, resulting in regurgitation of blood and heart failure, prompt surgical treatment should be performed to improve heart function.…”
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3920
Resveratrol—A Promising Therapeutic Agent with Problematic Properties
Published 2025-01-01“…This review summarizes the mechanisms of the biological effects of resveratrol, determined in vitro and in vivo, and the main limitations of the drug. The article emphasizes new approaches for the improvement of resveratrol delivery, in particular nanoencapsulation, formation of nanocrystals, prodrugs and structure analogues.…”
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