Reform and Development of Rare Diseases Drug Evaluation and Approval in China by HUANG Guo, YANG Zhimin, TANG Ling, ZHANG Jie, AI Xing, SE RI Geleng, ZHAO Tian

Subjects: Get full text

Design and Optimization of the Circulatory Cell-Driven Drug Delivery Platform by Pengyu Gao, Dan Zou, Ansha Zhao, Ping Yang

“…Achievement of high targeting efficiency for a drug delivery system remains a challenge of tumor diagnoses and nonsurgery therapies. …”
Get full text

Exploring Drug Targets in Isoprenoid Biosynthetic Pathway for Plasmodium falciparum by Tabish Qidwai, Farrukh Jamal, Mohd Y. Khan, Bechan Sharma

“…Emergence of rapid drug resistance to existing antimalarial drugs in Plasmodium falciparum has created the need for prediction of novel targets as well as leads derived from original molecules with improved activity against a validated drug target. …”
Get full text

Drug-induced differential culturability in diverse strains of Mycobacterium tuberculosis by Valerie F. A. March, Nino Maghradze, Kakha Mchedlishvili, Teona Avaliani, Rusudan Aspindzelashvili, Zaza Avaliani, Maia Kipiani, Nestani Tukvadze, Levan Jugheli, Selim Bouaouina, Anna Doetsch, Galo A. Goig, Sebastien Gagneux, Sonia Borrell

“…Here we provide evidence that drug exposure affects culturability on solid medium in diverse Mtb strains, which has implications for treatment monitoring and drug-pathogen interaction studies.…”
Get full text

Value systems and participation in drug trafficking activities in Sonora, Mexico by Francisco Manuel Piña-Osuna

Subjects: Get full text

The advancement of nanosystems for drug delivery in the prevention and treatment of dental caries by Han Du, Zheng Wang, Shenglan Long, Yiding Li, Deqin Yang, Deqin Yang, Deqin Yang

Subjects: Get full text

Comprehensive evaluation of pure and hybrid collaborative filtering in drug repurposing by Clémence Réda, Jill-Jênn Vie, Olaf Wolkenhauer

Subjects: “…Drug repositioning…”
Get full text

Advancement of Nanofibrous Mats and Common Useful Drug Delivery Applications by Hamza Abu Owida, Jamal I. Al-Nabulsi, Feras Alnaimat, Ashraf Al Sharah, Muhammad Al-Ayyad, Nidal M. Turab, Mustafa Abdullah

“…Electrospinning enables simple and cost-effective production of polymer nanofibers from different polymer materials. Drug delivery systems are capable of achieving maximum drug treatment benefits by significantly reducing adverse complications. …”
Get full text

A model for transmission of partial resistance to anti-malarial drugs by Hengki Tasman, Edy Soewono, Kuntjoro Adji Sidarto, Din Syafruddin, William Oscar Rogers

Subjects: Get full text

Conductive Composite Biosensor System for Electrochemical Indinavir Drug Detection by Natasha Ross, Nicolette Hendricks-Leukes, Rachel Fanelwa Ajayi, Priscilla Baker, Emmanuel I. Iwuoha

“…Indinavir is a protease inhibitor antiretroviral (ARV) drug, which forms part of the highly active antiretroviral therapy during the treatment of HIV/AIDS. …”
Get full text

Drug Therapy for Non-Alcoholic Steatohepatitis-Induced Liver Fibrosis by D. V. Garbuzenko

Subjects: Get full text

Multi-Omics and Network-Based Drug Repurposing for Septic Cardiomyopathy by Pei-Pei Liu, Xin-Yue Yu, Qing-Qing Pan, Jia-Jun Ren, Yu-Xuan Han, Kai Zhang, Yan Wang, Yin Huang, Tao Ban

“…This study aimed to identify repurposable drugs for SCM by integrated multi-omics and network analyses. …”
Get full text

Transdermal patches: Design and current approaches to painless drug delivery by Al Hanbali Othman A., Khan Haji Muhammad Shoaib, Sarfraz Muhammad, Arafat Mosab, Ijaz Shakeel, Hameed Abdul

Subjects: Get full text

Drug consumption and treatment costs of the glaucoma therapy in the Republic of Serbia by Ćoškov Aleksandra D., Savanović Dijana R., Todorović Nemanja B., Lalić-Popović Mladena N., Tomić Nataša Z., Milijašević Boris Ž.

Subjects: Get full text

Anticancer effects of olive oil polyphenols and their combinations with anticancer drugs by Torić Jelena, Marković Ana Karković, Brala Cvijeta Jakobušić, Barbarić Monika

“…One approach to the issue is chemoprevention and the other one is the discovery of more effective drugs or drug combinations, including combinations with polyphenols. …”
Get full text

Biopharmaceutical classification of desloratadine – not all drugs are classified the easy way by Berginc Katja, Sibinovska Nadica, Žakelj Simon, Trontelj Jurij, Legen Igor

“…The biopharmaceutical classification of drugs was designed as a basis for bio-waivers – a mechanism with the double ethical benefit of delivering new drug formulations to the market with less human testing and lower cost. …”
Get full text

The Possible Potential Therapeutic Targets for Drug Induced Gingival Overgrowth by Tamilselvan Subramani, Vidhya Rathnavelu, Noorjahan Banu Alitheen

“…Gingival overgrowth is a side effect of certain medications. The most fibrotic drug-induced lesions develop in response to therapy with phenytoin, the least fibrotic lesions are caused by cyclosporin A, and the intermediate fibrosis occurs in nifedipine-induced gingival overgrowth. …”
Get full text

Case of acute drug-induced hepatitis after halothane anesthesia by I. Yu. Pirogova, Ye. V. Berestova, O. Yu. Bastrikov, Ye. B. Kovaleva, T. P. Petukhova, M. V. Guseva, I. A. Gubina, I. V. Rezepin, S. P. Sinitsyn

Subjects: “…acute drug-induced hepatitis…”
Get full text

Should the Food and Drug Administration Limit Placebo-Controlled Trials? by Max Goodman, Connor Pedersen

Subjects: “…Food and Drug Administration…”
Get full text

Prospective de novo drug design with deep interactome learning by Kenneth Atz, Leandro Cotos, Clemens Isert, Maria Håkansson, Dorota Focht, Mattis Hilleke, David F. Nippa, Michael Iff, Jann Ledergerber, Carl C. G. Schiebroek, Valentina Romeo, Jan A. Hiss, Daniel Merk, Petra Schneider, Bernd Kuhn, Uwe Grether, Gisbert Schneider

“…Abstract De novo drug design aims to generate molecules from scratch that possess specific chemical and pharmacological properties. …”
Get full text