Blood coagulation monitoring of patients with mechanical heart valve visiting Imam by Nafiseh Montazeri, Sajad Pourmehr, Arash Ziapour, Reza Heidari Moghadam

“…Therefore, it is necessary to closely monitor patients’ blood coagulation for the appropriate therapeutic dose according to patients’ sex, education, blood pressure, captopril drug and the number of visits and follow-up.…”
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Effectiveness of a Protective Barrier for Aerosol Transmission Control during Oxygen Therapy with Different Devices by Hsiu-Mei Chang, Ben-Ran Fu, Hao-Wei Yu, Fu-Tsai Chung, Chen-June Seak, Ying-Chun Chen, Shih-Cheng Hu

“…The effects of nebulized drug delivery on aerosol concentration were also investigated. …”
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Case report: A panorama gene profile of ovarian cancer metastasized to axillary lymph node by Yu Xia, Yu Huang, Zheng Liu, Siyuan Song, Yi Wang, Yi Wang, Jing Luo

“…This study unraveled the potential mechanism of genetic mutation for tumor metabolism, drug resistance, and metastasis.…”
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Cost-Minimization Analysis for Subcutaneous Daratumumab in the Treatment of Newly Diagnosed Multiple Myeloma in Three Gulf Countries by Anas Hamad, Shereen Elazzazy, Ruba Y. Taha, Hani Osman, Sana Alblooshi, Islam Elkonaissi, Mustaqeem A. Siddiqui, Khalil Al-Farsi, Mohammed Al Lamki, Sali Emara, Gihan H. Elsisi

“…**Results:** The model showed that the use of dara-SC in NDMM patients who were eligible or ineligible for ASCT resulted in lower non-drug costs, including premedication drug costs, adverse-effect costs, administration costs, medical staff costs, and indirect costs. …”
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Naturally occurring variation in a cytochrome P450 modifies thiabendazole responses independently of beta-tubulin. by J B Collins, Clayton M Dilks, Steffen R Hahnel, Briana Rodriguez, Bennett W Fox, Elizabeth Redman, Jingfang Yu, Brittany Cooke, Kateryna Sihuta, Mostafa Zamanian, Peter J Roy, Frank C Schroeder, John S Gilleard, Erik C Andersen

“…Resistance to the benzimidazole (BZ) drug class is nearly ubiquitous in many species and is associated with mutations in beta-tubulin genes. …”
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Retrospective database analysis on the demographics and resource utilization of patients with Parkinson’s disease in Quebec, Canada by Véronique Baribeau, Shawn Mohammed, Amnah Awan, Diana Parison, Jean Lachaine

“…Adherence rates were high (≥85 %) among all drug classes, but lower with dopamine agonists. Persistence to PD treatment declined over time, with nearly 50 % discontinuation rates at 24 months in all PD drug classes, except the levodopa class (discontinuation rate: 20.4 %). …”
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Efficacy of osmotic laxative polyethylene glycol 4000 in treatment of constipation in pediatrics by S. I. Erdes, B. O. Matsukatova, S. A. Revyakina, Ye. V. Casanave

“…At the same time scores representing electrical activity of the large intestine, remained subnormal both prior and after course of treatment. In no patients drug side effects were not observed.Conclusions. …”
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Antimicrobial Usage by Small-Scale Commercial Poultry Farmers in Mid-Western District of Masindi Uganda: Patterns, Public Health Implications, and Antimicrobial Resistance of E. co... by Majalija Samuel, Tony Fredrick Wabwire, Gabriel Tumwine, Peter Waiswa

“…Only 10.7% observed the drug withdrawal period, while 53.6% consumed eggs at home or sold eggs (35.7%) from birds under treatment. …”
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Use of Stiripentol in Patients with Dravet Syndrome: Common Practice Among Experts in Spain by Juan José García-Peñas, Rocío Calvo-Medina, Adrián García-Ron, Antonio Gil-Nagel, Vicente Villanueva, Rocío Sánchez-Carpintero

“…Individualized adjustment of concomitant ASMs, such as valproic acid and clobazam or drugs specifically for DS (i.e., fenfluramine), at initiation and during stiripentol treatment, can mitigate drug interactions, thereby increasing the long-term tolerability of stiripentol treatment. …”
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Revealing speckle obscured living human retinal cells with artificial intelligence assisted adaptive optics optical coherence tomography by Vineeta Das, Furu Zhang, Andrew J. Bower, Joanne Li, Tao Liu, Nancy Aguilera, Bruno Alvisio, Zhuolin Liu, Daniel X. Hammer, Johnny Tam

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Interactions of Self-Assembled <i>Bletilla Striata</i> Polysaccharide Nanoparticles with Bovine Serum Albumin and Biodistribution of Its Docetaxel-Loaded Nanoparticles by Guangyuan Zhang, Jin Qiao, Xin Liu, Yuran Liu, Ji Wu, Long Huang, Danyang Ji, Qingxiang Guan

“…The effects of DS values on the properties of BSPs-SA nanoparticles were evaluated. Drug state, cytotoxicity, and histological studies were carried out. …”
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Pain in pancreatitis: issue and ways out by A. V. Okhlobystin

“…Besides enzymes, antisecretory drugs represent another integral component of CP patients treatment. …”
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Trend of Soil-Transmitted Helminths in Ethiopian Children: A Systematic Review and Meta-Analysis (2000-2018) by Getaneh Alemu, Feleke Mekonnen, Mezgebu Nega, Chalachew Muluneh

“…As a result, the nation has been implementing mass drug administration, water, sanitation, and hygiene and health extension programs to control those parasites. …”
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A Soft Landing Approach for the Centrifugal Microgel Synthesis Process by Badalan, Matei, Adisson, Lucie, Boldron, Arthur, Achard, Jean-Luc, Ghigliotti, Giovanni, Balarac, Guillaume, Bottausci, Frédéric

“…This represents a significant limitation of this technology, since capsule shape regularity is an important requirement for various biomedical applications (e.g. cell therapy implants, drug delivery). In this article we propose and validate experimentally an adaptation of the centrifugal microencapsulation, based on the concept of “soft landing” [1]. …”
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Targeted therapy and immunotherapy for gastric cancer: rational strategies, novel advancements, challenges, and future perspectives by Dong Luo, Yunmei Liu, Zhengmao Lu, Lei Huang

“…In particular, markable breakthroughs have been made in HER2-targeting drugs for HER2-positive GC patients. To address intrinsic and acquired resistances to HER2-targeting drugs, novel therapeutic agents including bispecific antibodies and antibody–drug conjugates (ADC) targeting HER2 have been developed. …”
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Circulating MicroRNAs in Elderly Type 2 Diabetic Patients by Giuseppina Catanzaro, Zein Mersini Besharat, Martina Chiacchiarini, Luana Abballe, Claudia Sabato, Alessandra Vacca, Paola Borgiani, Francesco Dotta, Manfredi Tesauro, Agnese Po, Elisabetta Ferretti

“…Intra- and intergroup comparison of miRNA profiles pinpointed three miRNAs that correlated with responses to sitagliptin: miR-378, which is a candidate biomarker of resistance to this DPP-IVi, and miR-126-3p and miR-223, which are associated with positive responses to the drug. The translational implications are as immediate as evident, with the possibility to develop noninvasive diagnostic tools to predict drug response and development of chronic complications.…”
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Targeting Caveolin‐1 in Multiple Myeloma Cells Enhances Chemotherapy and Natural Killer Cell‐Mediated Immunotherapy by Dewen Zhan, Zhimin Du, Shang Zhang, Juanru Huang, Jian Zhang, Hui Zhang, Zhongrui Liu, Eline Menu, Jinheng Wang

“…Here, it is found that caveolin‐1 (CAV1), a primary component of membrane lipid rafts and caveolae, is highly expressed in MM cells and is associated with MM progression and drug resistance. CAV1 knockdown decreases MM cell adhesion to stromal cells and attenuates cell adhesion‐mediated drug resistance to bortezomib. …”
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Accidental and Deliberate Self-Poisoning with Medications and Medication Errors among Children in Rural Sri Lanka by Kavinda Dayasiri, S. F. Jayamanne, C. Y. Jayasinghe

“…This study brings to light the burden of medicinal drug-related poisoning morbidity among children in rural Sri Lanka. …”
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Mechanisms of Copper-Induced Autophagy and Links with Human Diseases by Yuanyuan Fu, Shuyan Zeng, Zhenlin Wang, Huiting Huang, Xin Zhao, Min Li

“…Since the success of platinum-based compounds in the clinical treatment of various types of neoplasias, metal-based drugs have shown encouraging perspectives for drug development. …”
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Advances in cardiac organoid research: implications for cardiovascular disease treatment by Ziteng Huang, Keran Jia, Yadan Tan, Yang Yu, Wudian Xiao, Xiangyu Zhou, Jingyan Yi, Chunxiang Zhang

“…This approach is vital for enhancing precision and efficiency in drug development, allowing for more effective therapeutic strategies. …”
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