Small Bowel Cocoon: A Distinct Disease with a New Developmental Etiology by Ibrahim E. Bassiouny, Tariq O. Abbas

“…Neither had a history of previous surgery, peritonitis, or prolonged drug therapy. The distinct features of this disease are illustrated. …”
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Study on the Role of the Inclusion Complexes with 2-Hydroxypropyl-β-cyclodextrin for Oral Administration of Amiodarone by Andreea Creteanu, Daniela Pamfil, Cornelia Vasile, Gladiola Tantaru, Cristina Mihaela Ghiciuc, Lacramioara Ochiuz, Alina Ghilan, Ana Maria Macsim

“…The aim of this study was to improve the solubility of amiodarone hydrochloride (AMD) and the drug release using its inclusion complexes with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD). …”
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Early amiodarone or lidocaine administration during in-hospital cardiac arrest caused by shockable rhythms by Rafael C. Paganoni, Jack C. Pluenneke, Adham M. Mohamed, Charles H. Hayes, III, Carole E. Freiberger-O’Keefe, Paul S. Chan

“…A multivariable logistic regression model was constructed to evaluate the association between (1) time to drug administration and (2) drug administration prior to the second defibrillator shock on both survival outcomes. …”
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Production of Hydrophobic Microparticles at Safe-To-Inject Sizes for Intravascular Administration by Francisca L. Gomes, Francisco Conceição, Liliana Moreira Teixeira, Jeroen Leijten, Pascal Jonkheijm

“…<b>Background/Objectives:</b> Hydrophobic microparticles are one of the most versatile structures in drug delivery and tissue engineering. These constructs offer a protective environment for hydrophobic or water-sensitive compounds (e.g., drugs, peroxides), providing an optimal solution for numerous biomedical purposes, such as drug delivery or oxygen therapeutics. …”
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Catastrophic Brain Aspergillosis after Liver Transplantation by Mohammadmahdi Abbasi, Shirin Shams Ardakani, Nasir Fakhar, Hamid Eshaghi, Hosein Alimadadi, Toktam Faghihi, Behdad Gharib, Meisam Sharifzadeh, Masoomeh Safaei

“…Chemoprevention with triazoles, echinocandins, and polyenes is also effective. Voriconazole is the drug of choice for aspergillosis treatment. Although voriconazole is a highly effective antifungal drug, cerebral aspergillosis is often fatal.…”
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Effect of Denosumab on Bone Mineral Density of Hematopoietic Stem Cell Transplantation Recipients by Chaiho Jeong, Hee-Je Kim, Seok Lee, Moo Il Kang, Jeonghoon Ha

“…No serious symptomatic hypocalcaemia was observed. Serious adverse drug reactions requiring drug discontinuation were not observed. …”
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Commitment, partnerships and operational research: three priorities for 11 EMR countries to achieve TB elimination by M. van den Boom, K. Bennani, G. B. Migliori, L. D’Ambrosio, R. Centis, A. Parvez Sayed, H. Y. Atta, Y. Hutin

“…RESULTS: Implementation was sufficient (≥74%) for 5 of 8 domains, highest for TB infection management, TB preventive treatment, laboratory service, drug management, drug-resistant TB and TB-HIV collaboration (89%, 83% and 78%, respectively). …”
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A Comprehensive Review of the Diversity of Fungal Secondary Metabolites and Their Emerging Applications in Healthcare and Environment by Khushbu Wadhwa, Neha Kapoor, Hardeep Kaur, Eman A. Abu-Seer, Mohd. Tariq, Sazada Siddiqui, Virendra Kumar Yadav, Parwiz Niazi, Pankaj Kumar, Saad Alghamdi

“…In healthcare, it is being used as an antimicrobial, anticancer, anti-inflammatory, and immunosuppressive drug. The usage of modern tools of biotechnology can achieve an increase in demand for these SMs and large-scale production. …”
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The Role of Motility Impairment in the Pathogenesis of Functional Disorders of the Gastrointestinal Tract and Modern Possibilities for Their Treatment (Resolution of an Expert Coun... by I. V. Maev, A. S. Trukhmanov, A. A. Sheptulin, V. I. Simanenkov, S. R. Abdulhakov, N. A. Agafonova, V. A. Akhmedov, T. A. Ilchishina, M. G. Ipatova, O. V. Krapivnaya, Yu. A. Kucheryavyi, M. F. Osipenko, O. A. Storonova, G. N. Tarasova, G. Ya. Khismatullina, S. V. Cheryomushkin

“…At the same time, the advantages of the mebeverin antispasmodic drug, as well as the high efficiency and safety of the itopride hydrochloride prokinetic drug were noted. …”
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Efficacy of Hymecromone in Post-Cholecystectomy Patients by A V. Okhlobystin, A. К. Ufimtseva, M. A. Tatarkina, O. Z. Okhlobystina, V. T. Ivashkin

“…Hymecromone demonstrated itself to be an effective and safe drug, that may be applied both in standard and half dose. …”
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Delusions of Glass Under Skin: An Unusual Case of Somatic-Type Delusional Disorder Treated with Olanzapine by Nicholas Comardelle, Amber Edinoff, Juliana Fort

“…The patient was admitted to the psychiatry service, where organic causes were ruled out (infection, metabolic abnormalities, drug use). The patient received olanzapine 5mg PO nightly treatment with adjunctive psychotherapy and experienced acute psychotic relief after a two-day admission period. …”
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Modular access to saturated bioisosteres of anilines via photoelectrochemical decarboxylative C(sp3)–N coupling by Kang-Ning Yuan, Hongjun Zhuang, Jie Wei, Yu Shen, Hong-Qing Yao, Ming-Hong Li, Lin-Lin Xu, Ming Shang

“…Abstract In drug development, the substitution of benzene rings in aniline-based drug candidates with saturated bridged bicyclic ring systems often enhances pharmacokinetic properties while preserving biological activity. …”
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Efficient Self-Assembly of mPEG End-Capped Porous Silica as a Redox-Sensitive Nanocarrier for Controlled Doxorubicin Delivery by Anh Khoa Nguyen, Thi Hiep Nguyen, Bui Quoc Bao, Long Giang Bach, Dai Hai Nguyen

“…Porous nanosilica (PNS) has been regarded as a promising candidate for controlled delivery of anticancer drugs. Unmodified PNS-based nanocarriers, however, showed a burst release of encapsulated drugs, which may limit their clinical uses. …”
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Multi-organ frailty is enhanced by periodontitis-induced inflammaging by Yoshitaka Kase, Satoru Morikawa, Yuji Okano, Tatsuya Hosoi, Takazumi Yasui, Yoko Taki-Miyashita, Mitsutaka Yakabe, Maraku Goto, Kazuyuki Ishihara, Sumito Ogawa, Taneaki Nakagawa, Hideyuki Okano

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Active Management of Third Stage of Labor: Practice and Associated Factors among Obstetric Care Providers in North Wollo, Amhara Region, Ethiopia by Wondwosen Molla, Asresash Demissie, Marta Tessema

“…Practice was significantly associated with work experience, knowledge, the presence of assistance during third-stage management, and time of uterotonic drug preparation. Consistent and sustainable on job training and clinical audit should be applied in all facilities with regular supportive supervision and monitoring. …”
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A graph neural network approach for hierarchical mapping of breast cancer protein communities by Xiao Zhang, Qian Liu

“…These drugs include mercaptopurine, pioglitazone, and colchicine. …”
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Metal‐based nanomaterials and nanocomposites as promising frontier in cancer chemotherapy by Sunil Kumar, Monu Kumar Shukla, Abhishek Kumar Sharma, Gururaj K. Jayaprakash, Rajiv K. Tonk, Dinesh K. Chellappan, Sachin Kumar Singh, Kamal Dua, Faheem Ahmed, Sanjib Bhattacharyya, Deepak Kumar

“…To improve targeted drug delivery using nano‐carriers, noteworthy research is required. …”
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Design, synthesis and evaluation of benzofuran-acetamide scaffold as potential anticonvulsant agent by Shakya Ashok K., Kamal Mehnaz, Balaramnavar Vishal M., Bardaweel Sanna K., Naik Rajashri R., Saxena Anil K., Siddiqui H. H.

“…The pharmacophore mapping of the examined compounds on standard drugs (phenobarbital, phenytoin, ralitolin and carbamazepine) strongly suggests that these compounds may exert their anticonvulsant activity via the same established mechanism as that of known drugs.…”
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Crotalaria madurensis flavonol glycosides’ antibacterial activity against Staphylococcus aureus by Hala Sh. Mohammed, Salwa A. Abu El Wafa, Mona H. Ibrahim, Rasha Mohammad Fathy, Noha A. Seif-Eldein

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Simple and Selective HPLC-UV/Vis Bioanalytical Method to Determine Aluminum Phthalocyanine Chloride in Skin Permeation Studies by Thaiene Avila Reis, Ana Elise Jaculi, Rubens da Costa Alves, Tais Gratieri, Ricardo Bentes Azevedo, Graziella Anselmo Joanitti, Guilherme Martins Gelfuso, Marcilio Cunha-Filho

“…Lastly, the developed method was successfully tested in in vitro skin permeation studies of AlPcCl, proving its effectiveness in the development of pharmaceutical delivery systems containing this drug for topical photodynamic therapy of skin cancers.…”
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